287 research outputs found

    Off-farm processing : development of a forage collection scheduling model

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    The collection of straw and grasses for use in various industries is expanding, as there is a need for material in both the traditional forage markets and in the bio-products and bio­fuel industries. Because these materials tend to be bulky and difficult to transport there is a need for managers to optimize the performance of their collection process. The model focuses on two different types of collection, baled material and loose chops. The material is mowed, allowed to dry in field, and then collected with either a baler or a forage harvester. The model uses a combination of historical data and managerial inputs to compute the approximate costs of the material. The model also identifies the average and maximum delays involved in the collection of the material. These outputs allow a manager to identify areas where processing costs are high, and areas where there might be significant delays or excess capacity in the process. The model was verified by comparing results to information that was collected from two different facilities. One facility dealt primarily with fresh forage, while the other dealt exclusively with sun-cured forage. The model was verified to within 15% of the actual data, however, with continued refining of the input costs the modeled results can be much closer to actual operating costs. After verification, a number of scenarios were tested to determine the models’ greatest sensitivities. The effects of changing fuel costs, labour costs, and the length of the working day were all investigated. It was found that the repair and maintenance costs had a larger effect then either the fuel or labour costs for most types of equipment. It was also found that the model was very sensitive to the capacity of the equipment. For the model to provide an accurate representation of forage collection, the system must be adjusted to reflect the costs associated with a particular facility. After these adjustments are made, the operator can investigate the effects of changes on his/her particular operation

    A Decade On, How Has the Visibility of Energy Changed? Energy Feedback Perceptions from UK Focus Groups

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    The Smart Meter Rollout Programme in the UK has required energy suppliers to offer new smart meters to customers to provide near real-time energy use information and enable two-way communication between the meter and the central system. The provision was expected to result in meaningful energy reductions, but recent estimates suggest that these reductions may be as low as 2%. This paper contributes to the ongoing debate about the effectiveness of smart meters and in-home energy displays by providing insights on energy feedback perceptions from a series of focus groups with postgraduate consumers. In addition to domestic energy use, the study investigated how participants perceived their energy use at work and how they perceived the energy reduction efforts of their institutions and employers. A laddered and projective methodology was used to more deeply question participant perceptions and reveal their attitudes. The analysis of responses revealed a limited awareness around energy efficiency strategies and opportunities for more visual, mobile, engaging and target-driven interfaces for energy data. The findings also agree with previous observations that environmental concerns are not a key driver of energy reduction behaviours. This was shown by laddered questioning, not to be due to a lack of environmental concern, but rather the perception that reducing energy consumption would have negligible impact. A decade after in-home energy displays enabled a means of providing ‘visibility’ to ‘invisible’ energy consumption, little appears to have changed in the perception and experience of energy feedback

    Literature Review of Explainable Tabular Data Analysis

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    Explainable artificial intelligence (XAI) is crucial for enhancing transparency and trust in machine learning models, especially for tabular data used in finance, healthcare, and marketing. This paper surveys XAI techniques for tabular data, building on] previous work done, specifically a survey of explainable artificial intelligence for tabular data, and analyzes recent advancements. It categorizes and describes XAI methods relevant to tabular data, identifies domain-specific challenges and gaps, and examines potential applications and trends. Future research directions emphasize clarifying terminology, ensuring data security, creating user-centered explanations, improving interaction, developing robust evaluation metrics, and advancing adversarial example analysis. This contribution aims to bolster effective, trustworthy, and transparent decision making in the field of XAI

    Percussion hemoglobinuria - a novel term for hand trauma-induced mechanical hemolysis: a case report

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    <p>Abstract</p> <p>Introduction</p> <p>Extracorpuscular hemolysis caused by mechanical trauma has been well described in relation to lower extremity use, such as in soldiers and runners. Terms such as "march hemoglobinuria", "foot strike hemolysis" and "runners hemoglobinuria" have previously been coined and are easily recalled. Newer cases, however, are being identified in individuals vigorously using their upper extremities, such as drum players who use their hands to strike the instrument. Given the increased recognition of upper extremity-related mechanical hemolysis and hemoglobinuria in drummers, and the use of hand drumming worldwide, we would like introduce a novel term for this condition and call it "percussion hemoglobinuria".</p> <p>Case presentation</p> <p>A 24-year-old Caucasian man presented with reddish brown discoloration of his urine after playing the djembe drum. Urine examination after a rigorous practice session revealed blood on the dipstick, and 0 to 2 red blood cells per high power field microscopically. The urine sample was negative for myoglobulin. Other causes of hemolysis and hematuria were excluded and cessation of drum playing resulted in resolution of his symptoms.</p> <p>Conclusions</p> <p>The association of mechanical trauma-induced hemoglobinuria and playing hand percussion instruments is increasingly being recognized. We, however, feel that the true prevalence is higher than what has been previously recorded in the literature. By coining the term "percussion hemoglobinuria" we hope to raise the awareness of screening for upper extremity trauma-induced mechanical hemolysis in the evaluation of a patient with hemoglobinuria.</p

    Pharmacokinetics, safety, and tolerability of a depot formulation of naltrexone in alcoholics: an open-label trial

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    BACKGROUND: Naltrexone is an effective medication for treatment of alcohol dependence, but its efficacy is limited by lack of adherence to the oral dosage form. A long-acting depot formulation of naltrexone may increase adherence. METHODS: A single site, 6-week open label study was conducted with 16 alcohol dependent subjects each receiving 300 mg of Naltrexone Depot by intramuscular injection. The main outcomes were safety and tolerability of the Naltrexone Depot formulation, blood levels of naltrexone and its main metabolite 6-beta naltrexol, and self-reported alcohol use. All subjects received weekly individual counseling sessions. RESULTS: The medication was well tolerated with 88% of subjects completing the 6-week trial. The most common side effect experienced was injection site complications. There were no serious adverse events. Subjects had naltrexone and 6-beta-naltrexol concentrations throughout the trial with mean values ranging from 0.58 ng/mL to 2.04 ng/mL and 1.51 ng/mL to 5.52 ng/mL, respectively, at each sampling time following administration. Compared to baseline, subjects had significantly reduced number of drinks per day, heavy drinking days and proportion of drinking days. CONCLUSION: Naltrexone Depot is safe and well tolerated in alcoholics and these findings support the further investigation of its utility in larger double-blind placebo controlled trials

    A Regional Initiative to Reduce Skin Infections amongst Aboriginal Children Living in Remote Communities of the Northern Territory, Australia

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    Skin infections are endemic in many in remote Australian Aboriginal communities and have been linked to very high rates of chronic heart and kidney disease in this population. We report the results of a regional collaboration that aimed to reduce skin infections amongst children aged less than 15 years in five remote communities. The program included annual mass scabies treatment days offered to all residents and routine screening/follow-up of children. Trained community workers helped conduct over 6000 skin assessments on 2329 children over a three year period. Of every 100 children seen at the commencement of the study, 47 were found to have skin sores and many had multiple sores. We demonstrate a reduction both in the number of children with skin sores and in the severity of those sores. On average, of every 100 children seen per month, there were 14 fewer children with skin sores and seven fewer children with multiple sores. Overall improvement in treatment uptake was a critical factor. We found no discernible impact against scabies. While the burden of skin infections remains unacceptably high, we believe the results presented here are a good news story for local action to address a serious public health problem

    Pharmacotherapy for Alcohol Dependence: Anticraving Medications for Relapse Prevention

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    Alcohol dependence is a chronic disorder that results from a variety of genetic, psychosocial, and environmental factors. Relapse prevention for alcohol dependence has traditionally involved psychosocial and psychotherapeutic interventions. Pharmacotherapy, however, in conjunction with behavioral therapy, is generating interest as another modality to prevent relapse and enhance abstinence. Naltrexone and acamprosate are at the forefront of the currently available pharmacological options. Naltrexone is an opioid receptor antagonist and is thought to reduce the rewarding effect of alcohol. Acamprosate normalizes the dysregulation of N-methyl-D-aspartate (NMDA)-mediated glutamatergic excitation that occurs in alcohol withdrawal and early abstinence. These different mechanisms of action and different target neurotransmitter systems may endow the two drugs with efficacy for different aspects of alcohol use behavior. Since not all patients seem to benefit from naltrexone and acamprosate, there are ongoing efforts to improve the treatment outcomes by examining the advantages of combined pharmacotherapy and exploring the variables that might predict the response of the medications. In addition, novel medications are being investigated to assess their efficacy in preventing relapse and increasing abstinence
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