546 research outputs found
Photoassociation to the 2(1)Sigma(g)(+) state in ultracold 85Rb2 in the presence of a shape resonance
We report the first observation of photoassociation to the 2(1)Sigma(g)(+)
state of 85Rb2 . We have observed two vibrational levels (v'=98, 99) below the
5s1/2+5p1/2 atomic limit and eleven vibrational levels (v'=102-112) above it.
The photoassociation---and subsequent spontaneous emission---occur
predominantly between 15 and 20 Bohr in a region of internuclear distance best
described as a transition between Hund's case (a) and Hund's case (c) coupling.
The presence of a g-wave shape resonance in the collision of two ground-state
atoms affects the photoassociation rate and lineshape of the J'= 3 and 5
rotational levels.Comment: to appear in PR
Increasing age has limited impact on risk of Clostridium difficile infection in an elderly population
Infectious diseases consultation reduces 30-day and 1-year all-cause mortality for multidrug-resistant organism infections
Abstract
Background
Multidrug-resistant organism (MDRO) infections are associated with high mortality and readmission rates. Infectious diseases (ID) consultation improves clinical outcomes for drug-resistant Staphylococcus aureus bloodstream infections. Our goal was to determine the association between ID consultation and mortality following various MDRO infections.
Methods
This study was conducted with a retrospective cohort (January 1, 2006–October 1, 2015) at an academic tertiary referral center. We identified patients with MDROs in a sterile site or bronchoalveolar lavage/bronchial wash culture. Mortality and readmissions within 1 year of index culture were identified, and the association of ID consultation with these outcomes was determined using Cox proportional hazards models with inverse weighting by the propensity score for ID consultation.
Results
A total of 4214 patients with MDRO infections were identified. ID consultation was significantly associated with reductions in 30-day and 1-year mortality for resistant S. aureus (hazard ratio [HR], 0.48; 95% confidence interval [CI], 0.36–0.63; and HR, 0.73, 95% CI, 0.61–0.86) and Enterobacteriaceae (HR, 0.41; 95% CI, 0.27–0.64; and HR, 0.74; 95% CI, 0.59–0.94), and 30-day mortality for polymicrobial infections (HR, 0.51; 95% CI, 0.31–0.86) but not Acinetobacter or Pseudomonas. For resistant Enterococcus, ID consultation was marginally associated with decreased 30-day mortality (HR, 0.81; 95% CI, 0.62–1.06). ID consultation was associated with reduced 30-day readmission for resistant Enterobacteriaceae.
Conclusions
ID consultation was associated with significant reductions in 30-day and 1-year mortality for resistant S. aureus and Enterobacteriaceae, and 30-day mortality for polymicrobial infections. There was no association between ID consultation and mortality for patients with resistant Pseudomonas, Acinetobacter, or Enterococcus, possibly due to small sample sizes. Our results suggest that ID consultation may be beneficial for patients with some MDRO infections.
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Photoassociative Production and Trapping of Ultracold KRb Molecules
We have produced ultracold heteronuclear KRb molecules by the process of
photoassociation in a two-species magneto-optical trap. Following decay of the
photoassociated KRb*, the molecules are detected using two-photon ionization
and time-of-flight mass spectroscopy of KRb. A portion of the metastable
triplet molecules thus formed are magnetically trapped. Photoassociative
spectra down to 91 cm below the K(4) + Rb (5) asymptote have
been obtained. We have made assignments to all eight of the attractive Hund's
case (c) KRb* potential curves in this spectral region.Comment: 4 pages, 4 figure
The association of preoperative cardiac stress testing with 30-day death and myocardial infarction among patients undergoing kidney transplantation
BACKGROUND:Although periodic cardiac stress testing is commonly used to screen patients on the waiting list for kidney transplantation for ischemic heart disease, there is little evidence to support this practice. We hypothesized that cardiac stress testing in the 18 months prior to kidney transplantation would not reduce postoperative death, total myocardial infarction (MI) or fatal MI. METHODS:Using the United States Renal Data System, we identified ESRD patients ≥40 years old with primary Medicare insurance who received their first kidney transplant between 7/1/2006 and 11/31/2013. Propensity matching created a 1:1 matched sample of patients with and without stress testing in the 18 months prior to kidney transplantation. The outcomes of interest were death, total (fatal and nonfatal) MI or fatal MI within 30 days of kidney transplantation. RESULTS:In the propensity-matched cohort of 17,304 patients, death within 30 days occurred in 72 of 8,652 (0.83%) patients who underwent stress testing and in 65 of 8,652 (0.75%) patients who did not (OR 1.07; 95% CI: 0.79-1.45; P = 0.66). MI within 30 days occurred in 339 (3.9%) patients who had a stress test and in 333 (3.8%) patients who did not (OR 1.03; 95% CI: 0.89-1.21; P = 0.68). Fatal MI occurred in 17 (0.20%) patients who underwent stress testing and 15 (0.17%) patients who did not (OR 0.97; 95% CI: 0.71-1.32; P = 0.84). CONCLUSION:Stress testing in the 18 months prior to kidney transplantation is not associated with a reduction in death, total MI or fatal MI within 30 days of kidney transplantation
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