J/ψJ/\psi production and elliptic flow in relativistic heavy-ion collisions

Using a two-component model for charmonium production, which includes contributions from both the initial hard nucleon-nucleon scattering and from the regeneration in the quark-gluon plasma, we study the nuclear modification factor $R_{AA}$ and elliptic flow $v_2$ of $J/\psi$ in relativistic heavy ion collisions. For the expansion dynamics of produced hot dense matter, we introduce a schematic fireball model with its transverse acceleration determined from the pressure gradient inside the fireball and azimuthally anisotropic expansion parameterized to reproduce measured $v_2$ of light hadrons. We assume that light hadrons freeze out at the temperature of 120 MeV while charmonia at 160 MeV, similar to the kinetic and chemical freeze-out temperatures in the statistical model, respectively. For the properties of charmonia in the quark-gluon plasma, we use the screening mass between their charm and anticharm quarks and their dissociation cross sections given by the perturbative QCD (pQCD) in the leading order and up to the next-to-leading order, respectively. For the relaxation time of charm and anticharm quarks in the quark-gluon plasma, we also use the one calculated in the leading order of pQCD. Modeling the effect of higher-order corrections in pQCD by introducing multiplicative factors to the dissociation cross section of charmonia and the elastic scattering cross sections of charm and anticharm quarks, we find that this effect is small for the $R_{AA}$ of $J/\psi$ as they suppress the number of initially produced $J/\psi$ but enhance the number of regenerated ones. The higher-order corrections increase, however, the $v_2$ of $J/\psi$. Our results suggest that the $v_2$ of $J/\psi$ can play an important role in discriminating between $J/\psi$ production from the initial hard collisions and from the regeneration in the quark-gluon plasma.Comment: 15 pages, 14 figure

Effects of ion motion on linear Landau damping

The effects of ion motion on Landau damping has been studied by the use of one-dimensional Vlasov-Poisson simulation. It is shown that the ion motion may significantly change the development of the linear Landau damping. When the ion mass is multiple of proton mass, its motion will halt the linear Landau damping at some time due to the excitation of ion acoustic waves. The latter will dominate the system evolution at the later stage and hold a considerable fraction of the total energy in the system. With very small ion mass, such as in electron-positron plasma, the ion motion can suppress the linear Landau damping very quickly. When the initial field amplitude is relatively high such as with the density perturbation amplitude δn/n0 > 0.1, the effect of ion motion on Landau damping is found to be weak or even ignorable

Type-II Topological Dirac Semimetals: Theory and Materials Prediction (VAl3 family)

The discoveries of Dirac and Weyl semimetal states in spin-orbit compounds led to the realizations of elementary particle analogs in table-top experiments. In this paper, we propose the concept of a three-dimensional type-II Dirac fermion and identify a new topological semimetal state in the large family of transition-metal icosagenides, MA3 (M=V, Nb, Ta; A=Al, Ga, In). We show that the VAl3 family features a pair of strongly Lorentz-violating type-II Dirac nodes and that each Dirac node consists of four type-II Weyl nodes with chiral charge +/-1 via symmetry breaking. Furthermore, we predict the Landau level spectrum arising from the type-II Dirac fermions in VAl3 that is distinct from that of known Dirac semimetals. We also show a topological phase transition from a type-II Dirac semimetal to a quadratic Weyl semimetal or a topological crystalline insulator via crystalline distortions. The new type-II Dirac fermions, their novel magneto-transport response, the topological tunability and the large number of compounds make VAl3 an exciting platform to explore the wide-ranging topological phenomena associated with Lorentz-violating Dirac fermions in electrical and optical transport, spectroscopic and device-based experiments.Comment: 28 pages, 7 Figure

Dietary Intake of Fatty Acids, Total Cholesterol, and Stomach Cancer in a Chinese Population.

To investigate the associations between dietary fatty acids and cholesterol consumption and stomach cancer (SC), we analyzed data from a population-based case-control study with a total of 1900 SC cases and 6532 controls. Dietary data and other risk or protective factors were collected by face-to-face interviews in Jiangsu Province, China, from 2003 to 2010. Adjusted odds ratios (ORs) and 95% confidence intervals (CIs) were estimated using multiple unconditional logistic regression models and an energy-adjusted method. The joint associations between dietary factors and known risk factors on SC were examined. We observed positive associations between dietary saturated fatty acids (SFAs), monounsaturated fatty acids (MUFAs), and total cholesterol and the development of SC, comparing the highest versus lowest quarters. Increased intakes of dietary SFAs (p-trend = 0.005; aOR, 1.11; 95% CI, 1.01-1.22 with a 7 g/day increase as a continuous variable) and total cholesterol (p-trend < 0.001; aOR, 1.13; 95% CI, 1.06-1.22 with a 250 mg/day increase as a continuous variable) were monotonically associated with elevated odds of developing SC. Our results indicate that dietary SFAs, MUFAs, and total cholesterol are associated with stomach cancer, which might provide a potential dietary intervention for stomach cancer prevention

New fermions on the line in topological symmorphic metals

Topological metals and semimetals (TMs) have recently drawn significant interest. These materials give rise to condensed matter realizations of many important concepts in high-energy physics, leading to wide-ranging protected properties in transport and spectroscopic experiments. The most studied TMs, i.e., Weyl and Dirac semimetals, feature quasiparticles that are direct analogues of the textbook elementary particles. Moreover, the TMs known so far can be characterized based on the dimensionality of the band crossing. While Weyl and Dirac semimetals feature zero-dimensional points, the band crossing of nodal-line semimetals forms a one-dimensional closed loop. In this paper, we identify a TM which breaks the above paradigms. Firstly, the TM features triply-degenerate band crossing in a symmorphic lattice, hence realizing emergent fermionic quasiparticles not present in quantum field theory. Secondly, the band crossing is neither 0D nor 1D. Instead, it consists of two isolated triply-degenerate nodes interconnected by multi-segments of lines with two-fold degeneracy. We present materials candidates. We further show that triplydegenerate band crossings in symmorphic crystals give rise to a Landau level spectrum distinct from the known TMs, suggesting novel magneto-transport responses. Our results open the door for realizing new topological phenomena and fermions including transport anomalies and spectroscopic responses in metallic crystals with nontrivial topology beyond the Weyl/Dirac paradigm.Comment: 24 pages, 4 figures, and 1 tabl

A Microbiome-Based Index for Assessing Skin Health and Treatment Effects for Atopic Dermatitis in Children.

A quantitative and objective indicator for skin health via the microbiome is of great interest for personalized skin care, but differences among skin sites and across human populations can make this goal challenging. A three-city (two Chinese and one American) comparison of skin microbiota from atopic dermatitis (AD) and healthy pediatric cohorts revealed that, although city has the greatest effect size (the skin microbiome can predict the originated city with near 100% accuracy), a microbial index of skin health (MiSH) based on 25 bacterial genera can diagnose AD with 83 to ∼95% accuracy within each city and 86.4% accuracy across cities (area under the concentration-time curve [AUC], 0.90). Moreover, nonlesional skin sites across the bodies of AD-active children (which include shank, arm, popliteal fossa, elbow, antecubital fossa, knee, neck, and axilla) harbor a distinct but lesional state-like microbiome that features relative enrichment of Staphylococcus aureus over healthy individuals, confirming the extension of microbiome dysbiosis across body surface in AD patients. Intriguingly, pretreatment MiSH classifies children with identical AD clinical symptoms into two host types with distinct microbial diversity and treatment effects of corticosteroid therapy. These findings suggest that MiSH has the potential to diagnose AD, assess risk-prone state of skin, and predict treatment response in children across human populations.IMPORTANCE MiSH, which is based on the skin microbiome, can quantitatively assess pediatric skin health across cohorts from distinct countries over large geographic distances. Moreover, the index can identify a risk-prone skin state and compare treatment effect in children, suggesting applications in diagnosis and patient stratification

Efficacy of the Combination of Voriconazole and Caspofungin in Experimental Pulmonary Aspergillosis by Different Aspergillus Species

OBJECTIVES: Invasive pulmonary aspergillosis (IPA) caused by Aspergillus fumigatus, Aspergillus flavus, or Aspergillus niger is associated with high mortality. We evaluated the efficacy and compared the therapeutic effect differences of voriconazole (VRC) in combination with caspofungin (CAS) in transiently neutropenic rats infected by A. fumigatus, A. flavus, or A. niger. METHODS: Treatment groups consisted of VRC (10 mg/kg q12 h) monotherapy, CAS (1 mg/kg/day) monotherapy, combination of VRC (10 mg/kg q12 h) + CAS (1 mg/kg/day), and no drug for 10 consecutive days. The efficacy and the difference in the treatments were evaluated through prolongation of survival, reduction in serum galactomannan levels and residual fungal burden, and histological studies. RESULTS: For all the strains, the combination of VRC and CAS led to significant prolongation in survival (P < 0.05) and reduction in residual fungal burden (P < 0.05) compared with CAS alone, and decrease in serum galactomannan levels (P < 0.05) compared with either agent alone. The survival in the combined therapy groups was significantly improved compared to VRC monotherapy for the strains of A. flavus and A. niger (P < 0.05), but no significant difference for the strains of A. fumigatus (P > 0.05). CONCLUSIONS: Combination of VRC and CAS was synergistic in IPA by A. flavus and A. niger, but small efficacy benefits in IPA by A. fumigatus