Understanding the Wisdom of a People

Students will compare Yoruba and United States values

Comparing the Wisdom of Places: Nigerian Yoruba Proverbs and Colonial American Proverbs of Benjamin Franklin

Students will see similarities between proverbs from Nigeria and Colonial America

Mystery Class for Math

Using Mystery Class (website), students will calculate photoperiods and analyze data

An Illustrated Monsoon

Students will understand the meaning of the word monsoon and compare their climate to Indian climates

Reading a Map in Any Language

The students will cooperatively use map-reading skills to discover the physical and political geography of Bangladesh

Reading a Map in Any Language

The students will cooperatively use map-reading skills to discover the physical and political geography of Chile

Cellular and humoral immune responses and protection against schistosomes induced by a radiation-attenuated vaccine in chimpanzees

The radiation-attenuated Schistosoma mansoni vaccine is highly effective in rodents and primates but has never been tested in humans, primarily for safety reasons. To strengthen its status as a paradigm for a human recombinant antigen vaccine, we have undertaken a small-scale vaccination and challenge experiment in chimpanzees (Pan troglodytes). Immunological, clinical, and parasitological parameters were measured in three animals after multiple vaccinations, together with three controls, during the acute and chronic stages of challenge infection up to chemotherapeutic cure. Vaccination induced a strong in vitro proliferative response and early gamma interferon production, but type 2 cytokines were dominant by the time of challenge. The controls showed little response to challenge infection before the acute stage of the disease, initiated by egg deposition. In contrast, the responses of vaccinated animals were muted throughout the challenge period. Vaccination also induced parasite-specific immunoglobulin M (IgM) and IgG, which reached high levels at the time of challenge, while in control animals levels did not rise markedly before egg deposition. The protective effects of vaccination were manifested as an amelioration of acute disease and overall morbidity, revealed by differences in gamma-glutamyl transferase level, leukocytosis, eosinophilia, and hematocrit. Moreover, vaccinated chimpanzees had a 46% lower level of circulating cathodic antigen and a 38% reduction in fecal egg output, compared to controls, during the chronic phase of infection

Monsoons: A Three Season Play

Students will enact and understand the causes of South Asia’s monsoon

Gunga Din: Using Literature to Understand India\u27s Colonial Past

Students use the Rudyard Kipling poem “Gunga Din” to understand India’s colonial past

Comparing Three World Heritages: the Taj Mahal, the Great Wall, and the Statue of Liberty

Students will be aware of similarities and differences between these three places