Частота стоматологічних захворювань у дітей

Изучена обращаемость детей за специализированной помощью в стоматологический центр медицинской академии. Установлено, что наиболее часто дети обращаются за специализированной медицинской помощью в связи с поражением твердых тканей зубов, околозубных тканей и слизистой оболочки полости рта. Значительно реже – по поводу других стоматологических заболеваний. Такая специфика структуры патологии органов ротовой полости требует нацеленных лечебно – профилактических и организационных мероприятий. There was studied the incidence of children visiting dental center of medical academy in need of medical aid. It was determined that most often children call for medical aid due to damages of hard tooth tissues, periodontium and mucous membrane of mouth cavity. More rarely they call for aid due to other dental diseases. Such specific character of structure of mouth cavity pathology requires specialized medical – preventive and organizational measures

Deesign and synthesis of novel inhibitors of inositol monophosphatase, potential drug candidates in the treatment of bipolar disorder

EThOS - Electronic Theses Online ServiceGBUnited Kingdo

Bis-Benzyl Protected 6-Amino Cyclitols are Poisenous to Pd/C Catalysed Hydrogenolysis of Benzyl Ethers

Pd/C and Pd(OH)2/C catalysts are both poisoned by bis-benzyl protected 6-aminocyclitols thereby inhibiting the hydrogenolysis of benzyl ethers but removing N-Cbz groups chemoselectively. This outcome was unaltered by the use of different hydrogen donors. Replacement of the C-6 nitrogen atom by oxygen resulted in the starting materials being fully deprotected under similar conditions. These findings add cyclitolamines to the list of amines/bases that are poisonous to Pd/C catalysts during hydrogenolysis. Pd/C and Pd(OH)2/C catalysts are both poisoned by bis-benzyl protected 6-aminocyclitols thereby inhibiting the hydrogenolysis of benzyl ethers but removing N-Cbz groups chemoselectively