1,245 research outputs found
The eccentricity in heavy-ion collisions from Color Glass Condensate initial conditions
The eccentricity in coordinate-space at midrapidity of the overlap zone in
high-energy heavy-ion collisions predicted by the -factorization
formalism is generically larger than expected from scaling with the number of
participants. We provide a simple qualitative explanation of the effect which
shows that it is not caused predominantly by edge effects. We also show that it
is quite insensitive to ``details'' of the unintegrated gluon distribution
functions such as the presence of leading-twist shadowing and of an extended
geometric scaling window. The larger eccentricity increases the azimuthal
asymmetry of high transverse momentum particles. Finally, we point out that the
longitudinal structure of the Color Glass Condensate initial condition for
hydrodynamics away from midrapidity is non-trivial but requires understanding
of large- effects.Comment: 8 pages, 7 figures; v3: added note regarding Qs2~n_part versus
Qs2~T_A, final version to appear in PR
Maintenance of glucose-sensitive insulin secretion of cryopreserved human islets with University of Wisconsin solution and ascorbic acid-2 glucoside
Normal human islet cells are an ideal source for pancreas-targeted cell therapies, but the availability of human donor pancreata for islet isolation is severely limited. To effectively utilize such scarce donor organs for cell therapies, it is crucial to develop an excellent isolation, effective cryopreservation, and efficient gene transfer techniques for the transportation of isolated cells. In the present study, we investigate the effect of University of Wisconsin (UW) solution and ascorbic acid-2 glucoside (AA2G) on the cryopreservation of human islets. We also evaluate the gene transfer efficiency of a lentiviral vector expressing the E. coli LacZ gene, Lt-NLS/LacZ, in human islets. Human islets were isolated with a standard digestion method at the University of Alberta. Isolated islets were transported to Japan for 40 h and then subjected to cryopreservation experiments. The following preservation solutions were tested: UW solution with 100 mug/mL of AA2G, UW solution, 100% fetal bovine serum (FBS), and CMRL supplemented with 10% FBS. Following three months of cryopreservation, the islets were thawed and analyzed for viability, glucose-sensitive insulin secretion, proinsulin gene expression profile, and in vivo engraftment. The islets were also subjected to monolayer formation with 804G-cell-line-derived extracellular matrix (ECM), followed by Lt-NLS/LacZ transduction. The viability, morphology, glucose-sensitive insulin secretion, proinsulin gene expression, and monolayer formation efficiency of the thawed cryopreserved islets are significantly better maintained by the use of UW solution. When AA2G (100 mug/mL) is combined with UW, such parameters are further improved. The adequate engraftment of UW + AA2G-cryopreserved human islets is achieved in the liver of nude mice. Efficient Lt-NLS/LacZ transduction is identified in monolayered islets cryopreserved with UW solution with AA2G. The present work demonstrates that the combination of UW solution with AA2G (100 mug/mL) would be a useful cryopreservation means for human islets. Human islets monolayer-cultured with 804G-derived ECM are efficiently transduced with a lentiviral vector Lt-NLS/LacZ
Threshold electronic structure at the oxygen K edge of 3d transition metal oxides: a configuration interaction approach
It has been generally accepted that the threshold structure observed in the
oxygen K edge X-ray absorption spectrum in 3d transition metal oxides
represents the electronic structure of the 3d transition metal. There is,
however, no consensus about the correct description. We present an
interpretation, which includes both ground state hybridization and electron
correlation. It is based on a configuration interaction cluster calculation
using a MO6 cluster. The oxygen K edge spectrum is calculated by annihilating a
ligand hole in the ground state and is compared to calculations representing
inverse photoemission experiments in which a 3d transition metal electron is
added. Clear differences are observed related to the amount of ligand hole
created in the ground state. Two "rules" connected to this are discussed.
Comparison with experimental data of some early transition metal compounds is
made and shows that this simple cluster approach explains the experimental
features quite well.Comment: 10 pages, submitted to Phys. Rev. B, tried to make a better PS file
Dynamical Gauge Symmetry Breaking in Extension of the Standard Model
We study the extension of the Standard model with a
strong U(1) coupling. We argue that current experiments limit this coupling to
be relatively large. The model is dynamically broken to the Standard model at the scale of a few TeV with all the extra gauge bosons
and the exotic quarks acquiring masses much larger than the scale of
electroweak symmetry breaking. Furthermore we find that the model leads to
large dynamical mass of the top quark and hence also breaks the electroweak
gauge symmetry. It therefore leads to large dynamical effects within the
Standard model and can partially replace the Higgs interactions.Comment: 4 pages, revtex, no figures; revised version predicting realistic
mass spectru
Using Advanced Mass Spectrometry Techniques to Fully Characterize Atmospheric Organic Carbon: Current Capabilities and Remaining Gaps
Organic compounds in the atmosphere vary widely in their molecular composition and chemical properties, so no single instrument can reasonably measure the entire range of ambient compounds. Over the past decade, a new generation of in-situ, field-deployable mass spectrometers has dramatically improved our ability to detect, identify, and quantify these organic compounds, but no systematic approach has been developed to assess the extent to which currently available tools capture the entire space of chemical identity and properties that is expected in the atmosphere. Reduced-parameter frameworks that have been developed to describe atmospheric mixtures are exploited here to characterize the range of chemical properties accessed by a suite of instruments. Multiple chemical spaces (e.g. oxidation state of carbon vs. volatility, and oxygen number vs. carbon number) were populated with ions measured by several mass spectrometers, with gas- and particle-phase -pinene oxidation products serving as the test mixture of organic compounds. Few gaps are observed in the coverage of the parameter spaces by the instruments employed in this work, though the full extent to which comprehensive measurement was achieved is difficult to assess due to uncertainty in the composition of the mixture. Overlaps between individual ions and regions in parameter space were identified, both between gas- and particle-phase measurements, and within each phase. These overlaps were conservatively found to account for little (<10%) of the measured mass. However, challenges in identifying overlaps and in accurately converting molecular formulas into chemical properties (such as volatility or reactivity) highlight a continued need to incorporate structural information into atmospheric measurements
Chemical Evolution of Atmospheric Organic Carbon over Multiple Generations of Oxidation
The evolution of atmospheric organic carbon (OC) as it undergoes oxidation has a controlling influence on concentrations of key atmospheric species, including particulate matter, ozone, and oxidants. However, the full characterization of OC over hours to days of atmospheric processing has been stymied by its extreme chemical complexity. Here we study the multigenerational oxidation of -pinene in the laboratory, characterizing products with several state-of-the-art analytical techniques. While quantification of some early-generation products remains elusive, full carbon closure is achieved (within uncertainty) by the end of the experiments. This enables new insights into the effects of oxidation on OC properties (volatility, oxidation state, and reactivity), and the atmospheric lifecycle of OC. Following an initial period characterized by functionalization reactions and particle growth, fragmentation reactions dominate, forming smaller species. After approximately one day of atmospheric aging, most carbon is sequestered in two long-lived reservoirs, volatile oxidized gases and low-volatility particulate matter
QCD in the nuclear medium and effects due to Cherenkov gluons
The equations of in-medium gluodynamics are proposed. Their classical lowest
order solution is explicitly shown for a color charge moving with constant
speed. For nuclear permittivity larger than 1 it describes emission of
Cherenkov gluons resembling results of classical electrodynamics. The values of
the real and imaginary parts of the nuclear permittivity are obtained from the
fits to experimental data on the double-humped structure around the away-side
jet obtained at RHIC. The dispersion of the nuclear permittivity is predicted
by comparing the RHIC, SPS and cosmic ray data. This is important for LHC
experiments. Cherenkov gluons may be responsible for the asymmetry of dilepton
mass spectra near rho-meson, observed in the SPS experiment with excess in the
low-mass wing of the resonance. This feature is predicted to be common for all
resonances. The "color rainbow" quantum effect might appear according to higher
order terms of in-medium QCD if the nuclear permittivity depends on color.Comment: 29 p., 4 figs; for "Phys. Atom. Nucl." volume dedicated to 80th
birthday of L.B. Okun; minor corrections on pp. 11 and 13 in v
Spintronics: Fundamentals and applications
Spintronics, or spin electronics, involves the study of active control and
manipulation of spin degrees of freedom in solid-state systems. This article
reviews the current status of this subject, including both recent advances and
well-established results. The primary focus is on the basic physical principles
underlying the generation of carrier spin polarization, spin dynamics, and
spin-polarized transport in semiconductors and metals. Spin transport differs
from charge transport in that spin is a nonconserved quantity in solids due to
spin-orbit and hyperfine coupling. The authors discuss in detail spin
decoherence mechanisms in metals and semiconductors. Various theories of spin
injection and spin-polarized transport are applied to hybrid structures
relevant to spin-based devices and fundamental studies of materials properties.
Experimental work is reviewed with the emphasis on projected applications, in
which external electric and magnetic fields and illumination by light will be
used to control spin and charge dynamics to create new functionalities not
feasible or ineffective with conventional electronics.Comment: invited review, 36 figures, 900+ references; minor stylistic changes
from the published versio
Report from the Expert Panel on the evaluation of the VRZs during the 2018/19 fishing season
In July 2018 ARK (the Association of Responsible Krill harvesting companies) launched a set of voluntary measures, known as ARK’s Commitment, which were proposed to improve the long-term sustainability of the krill fishery. The Commitment was initiated with support from Greenpeace, WWF and The Pew Charitable Trusts as a precautionary action whilst CCAMLR developed spatial management of the krill fishery in Area 48. The Commitment, which took the form of Voluntary Restriction Zones (VRZs), was implemented for the 2018-19 fishing season. The krill fishing fleet associated with ARK agreed to avoid fishing in an area of up to 40 km from penguin colonies in Subarea 48.1 during the penguin breeding season
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