Failure of Universality in Noncompact Lattice Field Theories

The nonuniversal behavior of two noncompact nonlinear sigma models is described. When these theories are defined on a lattice, the behavior of the order parameter (magnetization) near the critical point is sensitive to the details of the lattice definition. This is counter to experience and to expectations based on the ideas of universality.Comment: 24 pages, REVTeX version 3.0 with 4 embedded figures, provided separately in compressed-uuencoded postscript packed in a self-extracting csh script produced with uufiles. To appear in J. Math. Phys

Mapping Diversity of Publication Patterns in the Social Sciences and Humanities: An Approach Making Use of Fuzzy Cluster Analysis

&lt;b&gt;Purpose:&lt;/b&gt; To present a method for systematically mapping diversity of publication patterns at the author level in the social sciences and humanities in terms of publication type, publication language and co-authorship.&lt;br&gt;&lt;b&gt;Design/methodology/approach:&lt;/b&gt; In a follow-up to the hard partitioning clustering by Verleysen and Weeren in 2016, we now propose the complementary use of fuzzy cluster analysis, making use of a membership coefficient to study gradual differences between publication styles among authors within a scholarly discipline. The analysis of the probability density function of the membership coefficient allows to assess the distribution of publication styles within and between disciplines.&lt;br&gt;&lt;b&gt;Findings:&lt;/b&gt; As an illustration we analyze 1,828 productive authors affiliated in Flanders, Belgium. Whereas a hard partitioning previously identified two broad publication styles, an international one vs. a domestic one, fuzzy analysis now shows gradual differences among authors. Internal diversity also varies across disciplines and can be explained by researchers&#39; specialization and dissemination strategies.&lt;br&gt;&lt;b&gt;Research limitations:&lt;/b&gt; The dataset used is limited to one country for the years 2000-2011; a cognitive classification of authors may yield a different result from the affiliation-based classification used here.&lt;br&gt;&lt;b&gt;Practical implications:&lt;/b&gt; Our method is applicable to other bibliometric and research evaluation contexts, especially for the social sciences and humanities in non-Anglophone countries.&lt;br&gt;&lt;b&gt;Originality/value:&lt;/b&gt; The method proposed is a novel application of cluster analysis to the field of bibliometrics. Applied to publication patterns at the author level in the social sciences and humanities, for the first time it systematically documents intra-disciplinary diversity.&lt;b&gt;Purpose:&lt;/b&gt; To present a method for systematically mapping diversity of publication patterns at the author level in the social sciences and humanities in terms of publication type, publication language and co-authorship.&lt;br&gt;&lt;b&gt;Design/methodology/approach:&lt;/b&gt; In a follow-up to the hard partitioning clustering by Verleysen and Weeren in 2016, we now propose the complementary use of fuzzy cluster analysis, making use of a membership coefficient to study gradual differences between publication styles among authors within a scholarly discipline. The analysis of the probability density function of the membership coefficient allows to assess the distribution of publication styles within and between disciplines.&lt;br&gt;&lt;b&gt;Findings:&lt;/b&gt; As an illustration we analyze 1,828 productive authors affiliated in Flanders, Belgium. Whereas a hard partitioning previously identified two broad publication styles, an international one vs. a domestic one, fuzzy analysis now shows gradual differences among authors. Internal diversity also varies across disciplines and can be explained by researchers&#39; specialization and dissemination strategies.&lt;br&gt;&lt;b&gt;Research limitations:&lt;/b&gt; The dataset used is limited to one country for the years 2000-2011; a cognitive classification of authors may yield a different result from the affiliation-based classification used here.&lt;br&gt;&lt;b&gt;Practical implications:&lt;/b&gt; Our method is applicable to other bibliometric and research evaluation contexts, especially for the social sciences and humanities in non-Anglophone countries.&lt;br&gt;&lt;b&gt;Originality/value:&lt;/b&gt; The method proposed is a novel application of cluster analysis to the field of bibliometrics. Applied to publication patterns at the author level in the social sciences and humanities, for the first time it systematically documents intra-disciplinary diversity.</span

How to select a drug for the long-term treatment of chronic heart failure

Abstract First-line drugs for the treatment of chronic congestive heart failure should produce immediate symptomatic benefit, improve exercise tolerance, and thereby improve the quality of life. They should preferentially be active as monotherapy or at least reduce the need for comedication. The drugs must be safe and well tolerated by patients and change, in the end, the natural history of the disease, so that sudden death will be prevented and life expectancy improves. None of the currently available drugs satisfies all these criteria. Diuretics, digitalls, converting-enzyme inhibitors, and ibopamine come close to the described ideal

E-government dalam Penyelenggaraan Pemerintahan Daerah di Indonesia

Tulisan ini hendak mengkaji pemanfaatan E-Government (Electronic Government) dalam penyelenggaraan pemerintahan daerah di Indonesia dengan menggunakan perspektif yuridis. berupa pengaturan yang sudah ada pada tingkat nasional atau pusat serta saran tindak bagi daerah dalam rangka mengimplementasikan E-Government, terutama pijakan awalnya berupa suatu kerangka hukum (legal framework). Tulisan ini merupakan penelitian hukum dengan menggunakan pendekatan teoretis-konseptual (conceptual approach) dan pendekatan Perundang-undangan (statute approach)

Telaah Teoretis dan Yuridis Tukar Menukar Barang Milik Daerah dengan Swasta

This study brought up the problems, first, the theoretical foundation of the exchange of regional owned property (BMD) between local government and private parties. Second, the laws and regulations governing the exchange activities of BMD. Third, basic considerations in relation to the exchange of BMD. The type of the research was normative research. The results concluded that, first, theoretically, the government (local government) can do contractualization of governmentaffairs because this has become a practice (habit) in the government. The contractualisation includes exchange agreements with non-governmental parties that involve assets(land)thatare under government control (BMD). Second, juridically, the regulational basis for the exchange agreement serving as the basis for the right to transfer the assets (land) under government control (BMD) can be found in the legislation. In doing such actions, terms and conditions of legislation shall apply as the basis of the validity of the actions which includes the aspects of authority, substance and procedure. Third, another thing that determines the feasibility of government action in exchanging BMD (in the form of land) is the aspect of benefit (doelmatigheid)

The Quantized O(1,2)/O(2)×Z2O(1,2)/O(2)\times Z_2 Sigma Model Has No Continuum Limit in Four Dimensions. I. Theoretical Framework

The nonlinear sigma model for which the field takes its values in the coset space $O(1,2)/O(2)\times Z_2$ is similar to quantum gravity in being perturbatively nonrenormalizable and having a noncompact curved configuration space. It is therefore a good model for testing nonperturbative methods that may be useful in quantum gravity, especially methods based on lattice field theory. In this paper we develop the theoretical framework necessary for recognizing and studying a consistent nonperturbative quantum field theory of the $O(1,2)/O(2)\times Z_2$ model. We describe the action, the geometry of the configuration space, the conserved Noether currents, and the current algebra, and we construct a version of the Ward-Slavnov identity that makes it easy to switch from a given field to a nonlinearly related one. Renormalization of the model is defined via the effective action and via current algebra. The two definitions are shown to be equivalent. In a companion paper we develop a lattice formulation of the theory that is particularly well suited to the sigma model, and we report the results of Monte Carlo simulations of this lattice model. These simulations indicate that as the lattice cutoff is removed the theory becomes that of a pair of massless free fields. Because the geometry and symmetries of these fields differ from those of the original model we conclude that a continuum limit of the $O(1,2)/O(2)\times Z_2$ model which preserves these properties does not exist.Comment: 25 pages, no figure

Factors Associated with Xylene Exposure

Xylene is an ingredient that is most dominant in spray painting in the automotive industry. When the paint is sprayed, the worker will be exposed not only by the vapor, but also from the mist, a collection of fine particles in the form of a liquid. This study was conducted in one area of car painting in Surabaya. The aim of this study is to analyze factors associated with xylene exposrue. Car painter is a group of workers at risk for exposure to xylene. In addition, workers also do not know the dangers of exposure to xylene against him. This study was designed as an observational study conducted cross-sectional to analyze the relationship between levels of xylene exposure and characteristic of workshops in car painting area in Surabaya. Result of Spearman test for analyzing factors associated with xylene exposure showed a significant correlation on temperature and humidity. Based on the independent-samples t-test it can be concluded that there is a statistically significant difference between two conditions, if the cut off point of this comparison based on TLV, 100 ppm. As the conclusion, there is a relationship between characteristics of workshops with xylene exposure in car painting areas in Surabaya

Mononuclear cell transcriptome changes associated with dimethyl fumarate in MS.

ObjectiveTo identify short-term changes in gene expression in peripheral blood mononuclear cells (PBMCs) associated with treatment response to dimethyl fumarate (DMF, Tecfidera) in patients with relapsing-remitting MS (RRMS).MethodsBlood samples were collected from 24 patients with RRMS (median Expanded Disability Status Scale score, 2.0; range 1-7) at baseline, 6 weeks, and 15 months after the initiation of treatment with DMF (BG-12; Tecfidera). Seven healthy controls were also recruited, and blood samples were collected over the same time intervals. PBMCs were extracted from blood samples and sequenced using next-generation RNA sequencing. Treatment responders were defined using the composite outcome measure "no evidence of disease activity" (NEDA-4). Time-course and cross-sectional differential expression analyses were performed to identify transcriptomic markers of treatment response.ResultsTreatment responders (NEDA-4 positive, 8/24) over the 15-month period had 478 differentially expressed genes (DEGs) 6 weeks after the start of treatment. These were enriched for nuclear factor (erythroid-derived 2)-like 2 (Nrf2) and inhibition of nuclear factor κB (NFκB) pathway transcripts. For patients who showed signs of disease activity, there were no DEGs at 6 weeks relative to their (untreated) baseline. Contrasting transcriptomes expressed at 6 weeks with those at 15 months of treatment, 0 and 1,264 DEGs were found in the responder and nonresponder groups, respectively. Transcripts in the nonresponder group (NEDA-4 negative, 18/24) were enriched for T-cell signaling genes.ConclusionShort-term PBMC transcriptome changes reflecting activation of the Nrf2 and inhibition of NFκB pathways distinguish patients who subsequently show a medium-term treatment response with DMF. Relative stabilization of gene expression patterns may accompany treatment-associated suppression of disease activity