1,403 research outputs found
What is Ailing the German Economy? A Critical Analysis of German Social Market Economics
This paper offers a narrative historical description of the German Social Market Economy, from its inception following World War II, up to the recent Agenda 2010 reforms enacted under the administration of Chancellor Gerhard Schroder. It is the purpose of this work to explore why the German Social Market System enjoyed such a high degree of success in its early years, and which flaws might be causing the chronic problems of low growth and high unemployment that have plagued Germany more recently. In particular, the paper argues that a high-cost and highly inflexible labor market resulting from Germany\u27s system of autonomous collective wage bargaining may be stymieing business growth and scaring away foreign investment
Exploration of Alternative Methods of Providing Quality Educational Programs in Five Small Illinois Rural School Districts
This study explored alternative methods that might be used by five selected small Illinois rural school districts to provide quality educational programs. Many Illinois school districts are facing problems that are unique to today\u27s educational setting. Declining enrollments and decreasing farm land assessments along with small increases in state aid have compounded the problems of school districts. School board members must be aware of the condition of the school districts and what warning signs show impending problems. This study explored the enrollment projections, financial conditions and the instructional setting of five Shelby County Illinois school districts. Then options available to these districts to retain and enhance quality educational programs were explored. Conclusions were made with regard to the condition of these districts. With the information in the study and with careful evaluation, the members of the boards of education of these five school districts should be able to make more informed and appropriate decisions as to the direction each school district should take in the future
Hoodies in the Halls of Power: A Rhetorical Materialist Critique of Professional Decorum in the United States Senate
This brief paper explores the controversy surrounding Senator John Fetterman\u27s sartorial choices of casual attire in the hyper-professionalized space of the United States Senate. Fetterman\u27s clothing choices transcend mere fashion; they embody a statement of class identity and challenge the established power dynamics within the Senate. His attire reflects Pittsburgh\u27s industrial and labor-oriented history, in contrast to the conventional, affluent image most associated with politicians. Although controversial, Fetterman\u27s white male privilege minimized the consequences of his indecorous behavior. The reactions to Fetterman\u27s attire highlight the debate over what constitutes appropriate professional decorum, unveiling the underlying biases and demonstrating how something as mundane as clothing can become a potent symbol in professional and political communication. Through a rhetorical materialist critique of the Fetterman attire controversy, we reveal decorum as a raced, gendered, and imperialistic technology an elite ruling class leverages to preserve the existing order. Our analysis further articulates the implications of Fetterman\u27s attire regarding material inclusivity and tangible representation in professional settings. We propose that reevaluating traditional decorum standards is essential to accommodate the evolving diversity of modern society
Impact Factor: outdated artefact or stepping-stone to journal certification?
A review of Garfield's journal impact factor and its specific implementation
as the Thomson Reuters Impact Factor reveals several weaknesses in this
commonly-used indicator of journal standing. Key limitations include the
mismatch between citing and cited documents, the deceptive display of three
decimals that belies the real precision, and the absence of confidence
intervals. These are minor issues that are easily amended and should be
corrected, but more substantive improvements are needed. There are indications
that the scientific community seeks and needs better certification of journal
procedures to improve the quality of published science. Comprehensive
certification of editorial and review procedures could help ensure adequate
procedures to detect duplicate and fraudulent submissions.Comment: 25 pages, 12 figures, 6 table
<i>Gaia</i> Data Release 1. Summary of the astrometric, photometric, and survey properties
Context. At about 1000 days after the launch of Gaia we present the first Gaia data release, Gaia DR1, consisting of astrometry and photometry for over 1 billion sources brighter than magnitude 20.7.
Aims. A summary of Gaia DR1 is presented along with illustrations of the scientific quality of the data, followed by a discussion of the limitations due to the preliminary nature of this release.
Methods. The raw data collected by Gaia during the first 14 months of the mission have been processed by the Gaia Data Processing and Analysis Consortium (DPAC) and turned into an astrometric and photometric catalogue.
Results. Gaia DR1 consists of three components: a primary astrometric data set which contains the positions, parallaxes, and mean proper motions for about 2 million of the brightest stars in common with the HIPPARCOS and Tycho-2 catalogues – a realisation of the Tycho-Gaia Astrometric Solution (TGAS) – and a secondary astrometric data set containing the positions for an additional 1.1 billion sources. The second component is the photometric data set, consisting of mean G-band magnitudes for all sources. The G-band light curves and the characteristics of ∼3000 Cepheid and RR-Lyrae stars, observed at high cadence around the south ecliptic pole, form the third component. For the primary astrometric data set the typical uncertainty is about 0.3 mas for the positions and parallaxes, and about 1 mas yr−1 for the proper motions. A systematic component of ∼0.3 mas should be added to the parallax uncertainties. For the subset of ∼94 000 HIPPARCOS stars in the primary data set, the proper motions are much more precise at about 0.06 mas yr−1. For the secondary astrometric data set, the typical uncertainty of the positions is ∼10 mas. The median uncertainties on the mean G-band magnitudes range from the mmag level to ∼0.03 mag over the magnitude range 5 to 20.7.
Conclusions. Gaia DR1 is an important milestone ahead of the next Gaia data release, which will feature five-parameter astrometry for all sources. Extensive validation shows that Gaia DR1 represents a major advance in the mapping of the heavens and the availability of basic stellar data that underpin observational astrophysics. Nevertheless, the very preliminary nature of this first Gaia data release does lead to a number of important limitations to the data quality which should be carefully considered before drawing conclusions from the data
Electrochemical Studies of Fluorenone in Ionic Liquids and Aprotic Solvents
The electrochemical behavior of 9-fluorenone in acetonitrile / tetraethylammonium tetrafluoroborate (TEA BF 4 ) solutions has been explored by additions of 1-ethyl-3-methylimidazolium tetrafluoroborate (EMIm BF 4 ) and the proton donor 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP). The effect of EMIm BF 4 addition was found to be consistent with complexation of the dianion of 9-fluorenone by the EMIm cation, causing a positive shift of the second reduction process. Addition of HFIP as proton donor, on the other hand, caused the formation of a single reduction process near the first fluorenone reduction process
Radical SAM enzyme QueE defines a new minimal core fold and metal-dependent mechanism
7-carboxy-7-deazaguanine synthase (QueE) catalyzes a key S-adenosyl-L-methionine (AdoMet)- and Mg[superscript 2+]-dependent radical-mediated ring contraction step, which is common to the biosynthetic pathways of all deazapurine-containing compounds. QueE is a member of the AdoMet radical superfamily, which employs the 5′-deoxyadenosyl radical from reductive cleavage of AdoMet to initiate chemistry. To provide a mechanistic rationale for this elaborate transformation, we present the crystal structure of a QueE along with structures of pre- and post-turnover states. We find that substrate binds perpendicular to the [4Fe-4S]-bound AdoMet, exposing its C6 hydrogen atom for abstraction and generating the binding site for Mg[superscript 2+], which coordinates directly to the substrate. The Burkholderia multivorans structure reported here varies from all other previously characterized members of the AdoMet radical superfamily in that it contains a hypermodified ([β [subscript 6] over α [subscript 3]]) protein core and an expanded cluster-binding motif, CX[subscript 14]CX[subscript 2]C.United States. Dept. of Energy. Office of Biological and Environmental ResearchUnited States. Dept. of Energy. Office of Basic Energy SciencesNational Center for Research Resources (U.S.) (P41RR012408)National Institute of General Medical Sciences (U.S.) (P41GM103473)National Center for Research Resources (U.S.) (5P41RR015301-10)National Institute of General Medical Sciences (U.S.) (8 P41 GM 103403-10)United States. Dept. of Energy (Contract DE-AC02-06CH11357
Differentiation-Induced Remodelling of Store-Operated Calcium Entry Is Independent of Neuronal or Glial Phenotype but Modulated by Cellular Context
Neurogenesis is a complex process leading to the generation of neuronal networks and glial cell types from stem cells or intermediate progenitors. Mapping subcellular and molecular changes accompanying the switch from proliferation to differentiation is vital for developing therapeutic targets for neurological diseases. Neuronal (N-type) and glial (S-type) phenotypes within the SH-SY5Y neuroblastoma cell line have distinct differentiation responses to 9-cis-retinoic acid (9cRA). In both cell phenotypes, these were accompanied at the single cell level by an uncoupling of Ca2+ store release from store-operated Ca2+ entry (SOCE), mediated by changes in the expression of calcium release-activated calcium pore proteins. This remodelling of calcium signalling was moderated by the predominant cell phenotype within the population. N- and S-type cells differed markedly in their phenotypic stability after withdrawal of the differentiation inducer, with the phenotypic stability of S-type cells, both morphologically and with respect to SOCE properties, in marked contrast to the lability of the N-type phenotype. Furthermore, the SOCE response of I-type cells, a presumed precursor to both N- and S-type cells, varied markedly in different cell environments. These results demonstrate the unique biology of neuronal and glial derivatives of common precursors and suggest that direct or indirect interactions between cell types are vital components of neurogenesis that need to be considered in experimental models.</p
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