15,512 research outputs found

    Multivariable Repetitive-predictive Controllers using Frequency Decomposition

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    Repetitive control is a methodology for the tracking of a periodic reference signal. This paper develops a new approach to repetitive control systems design using receding horizon control with frequency decomposition of the reference signal. Moreover, design and implementation issues for this form of repetitive predictive control are investigated from the perspectives of controller complexity and the effects of measurement noise. The analysis is supported by a simulation study on a multi-input multi-output robot arm where the model has been constructed from measured frequency response data, and experimental results from application to an industrial AC motor

    Control of Coercivities in (Ga,Mn)As Thin Films by Small Concentrations of MnAs Nanoclusters

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    We demonstrate that low concentrations of a secondary magnetic phase in (Ga,Mn)As thin films can enhance the coercivity by factors up to ~100 without significantly degrading the Curie temperature or saturation magnetisation. Magnetic measurements indicate that the secondary phase consists of MnAs nanoclusters, of average size ~7nm. This approach to controlling the coercivity while maintaining high Curie temperature, may be important for realizing ferromagnetic semiconductor based devices.Comment: 8 pages,4 figures. accepted for publication in Appl. Phys. Let

    Targeting lentiviral vectors to antigen-specific immunoglobulins

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    Gene transfer into B cells by lentivectors can provide an alternative approach to managing B lymphocyte malignancies and autoreactive B cell-mediated autoimmune diseases. These pathogenic B cell Populations can be distinguished by their surface expression of monospecific immunoglobulin. Development of a novel vector system to deliver genes to these specific B cells could improve the safety and efficacy of gene therapy. We have developed an efficient rnethod to target lentivectors to monospecific immunoglobulin-expressing cells in vitro and hi vivo. We were able to incorporate a model antigen CD20 and a fusogenic protein derived from the Sindbis virus as two distinct molecules into the lentiviral Surface. This engineered vector could specifically bind to cells expressing Surface immunoglobulin recognizing CD20 (αCD20), resulting in efficient transduction of target cells in a cognate antigen-dependent manner in vitro, and in vivo in a xenografted tumor model. Tumor suppression was observed in vivo, using the engineered lentivector to deliver a suicide gene to a xenografted tumor expressing αCD20. These results show the feasibility of engineering lentivectors to target immunoglobulin-specific cells to deliver a therapeutic effect. Such targeting lentivectors also Could potentially be used to genetically mark antigen-specific B cells in vivo to study their B cell biology

    Resonant Cyclotron Radiation Transfer Model Fits to Spectra from Gamma-Ray Burst GRB870303

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    We demonstrate that models of resonant cyclotron radiation transfer in a strong field (i.e. cyclotron scattering) can account for spectral lines seen at two epochs, denoted S1 and S2, in the Ginga data for GRB870303. Using a generalized version of the Monte Carlo code of Wang et al. (1988,1989b), we model line formation by injecting continuum photons into a static plane-parallel slab of electrons threaded by a strong neutron star magnetic field (~ 10^12 G) which may be oriented at an arbitrary angle relative to the slab normal. We examine two source geometries, which we denote "1-0" and "1-1," with the numbers representing the relative electron column densities above and below the continuum photon source plane. We compare azimuthally symmetric models, i.e. models in which the magnetic field is parallel to the slab normal, with models having more general magnetic field orientations. If the bursting source has a simple dipole field, these two model classes represent line formation at the magnetic pole, or elsewhere on the stellar surface. We find that the data of S1 and S2, considered individually, are consistent with both geometries, and with all magnetic field orientations, with the exception that the S1 data clearly favor line formation away from a polar cap in the 1-1 geometry, with the best-fit model placing the line-forming region at the magnetic equator. Within both geometries, fits to the combined (S1+S2) data marginally favor models which feature equatorial line formation, and in which the observer's orientation with respect to the slab changes between the two epochs. We interpret this change as being due to neutron star rotation, and we place limits on the rotation period.Comment: LaTeX2e (aastex.cls included); 45 pages text, 17 figures (on 21 pages); accepted by ApJ (to be published 1 Nov 1999, v. 525

    Integrating fluctuations into distribution of resources in transportation networks

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    We propose a resource distribution strategy to reduce the average travel time in a transportation network given a fixed generation rate. Suppose that there are essential resources to avoid congestion in the network as well as some extra resources. The strategy distributes the essential resources by the average loads on the vertices and integrates the fluctuations of the instantaneous loads into the distribution of the extra resources. The fluctuations are calculated with the assumption of unlimited resources, where the calculation is incorporated into the calculation of the average loads without adding to the time complexity. Simulation results show that the fluctuation-integrated strategy provides shorter average travel time than a previous distribution strategy while keeping similar robustness. The strategy is especially beneficial when the extra resources are scarce and the network is heterogeneous and lowly loaded.Comment: 14 pages, 4 figure

    The effects of spatial constraints on the evolution of weighted complex networks

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    Motivated by the empirical analysis of the air transportation system, we define a network model that includes geographical attributes along with topological and weight (traffic) properties. The introduction of geographical attributes is made by constraining the network in real space. Interestingly, the inclusion of geometrical features induces non-trivial correlations between the weights, the connectivity pattern and the actual spatial distances of vertices. The model also recovers the emergence of anomalous fluctuations in the betweenness-degree correlation function as first observed by Guimer\`a and Amaral [Eur. Phys. J. B {\bf 38}, 381 (2004)]. The presented results suggest that the interplay between weight dynamics and spatial constraints is a key ingredient in order to understand the formation of real-world weighted networks

    On the influence of ram-pressure stripping on the star formation of simulated spiral galaxies

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    We investigate the influence of ram-pressure stripping on the star formation and the mass distribution in simulated spiral galaxies. Special emphasis is put on the question where the newly formed stars are located. The stripping radius from the simulation is compared to analytical estimates. Disc galaxies are modelled in combined N-body/hydrodynamic simulations (GADGET-2) with prescriptions for cooling, star formation, stellar feedback, and galactic winds. These model galaxies move through a constant density and temperature gas, which has parameters comparable to the intra-cluster medium (ICM) in the outskirts of a galaxy cluster (T=3 keV ~3.6x10^7 K and rho=10^-28 g/cm^3). With this numerical setup we analyse the influence of ram-pressure stripping on the star formation rate of the model galaxy. We find that the star formation rate is significantly enhanced by the ram-pressure effect (up to a factor of 3). Stars form in the compressed central region of the galaxy as well as in the stripped gas behind the galaxy. Newly formed stars can be found up to hundred kpc behind the disc, forming structures with sizes of roughly 1 kpc in diameter and with masses of up to 10^7 M_sun. As they do not possess a dark matter halo due to their formation history, we name them 'stripped baryonic dwarf' galaxies. We also find that the analytical estimate for the stripping radius from a Gunn & Gott (1972) criterion is in good agreement with the numerical value from the simulation. Like in former investigations, edge-on systems lose less gas than face-on systems and the resulting spatial distribution of the gas and the newly formed stars is different.Comment: 8 pages, 7 figures, accepted for publication in A&

    The Structure of the Star-forming Cluster RCW 38

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    We present a study of the structure of the high mass star-forming region RCW~38 and the spatial distribution of its young stellar population. Spitzer IRAC photometry 3-8um are combined with 2MASS near-IR data to identify young stellar objects by IR-excess emission from their circumstellar material. Chandra X-ray data are used to identify class III pre-main sequence stars lacking circumstellar material. We identify 624 YSOs: 23 class 0/I and 90 flat spectrum protostars, 437 Class II stars, and 74 Class III stars. We also identify 29 (27 new) O star candidates over the IRAC field. Seventy-two stars exhibit IR-variability, including seven class 0/I and 12 flat spectrum YSOs. A further 177 tentative candidates are identified by their location in the IRAC [3.6] vs. [3.6]-[5.8] cmd. We find strong evidence of subclustering in the region. Three subclusters were identified surrounding the central cluster, with massive and variable stars in each subcluster. The central region shows evidence of distinct spatial distributions of the protostars and pre-main sequence stars. A previously detected IR cluster, DB2001_Obj36, has been established as a subcluster of RCW 38. This suggests that star formation in RCW 38 occurs over a more extended area than previously thought. The gas to dust ratio is examined using the X-ray derived hydrogen column density, N_H and the K-band extinction, and found to be consistent with the diffuse ISM, in contrast with Serpens & NGC1333. We posit that the high photoionising flux of massive stars in RCW 38 affects the agglomeration of the dust grains.Comment: 98 pages, 15 figure
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