Education of women with disabilities in Pakistan: Enhanced agency, unfulfilled aspirations

This paper examines the extent to which the capability approach captures the complexity of the lives of young women with disabilities in Pakistan, particularly in relation to their education. Focusing on their educational experiences and outcomes, we examine the ways in which education shaped what these young women were able to achieve – what they wanted to do and be. In undertaking this research, we adopted a collaborative, qualitative approach involving in-depth interviews with six young women with disabilities. All these women were interesting and exemplary cases, given their very high levels of education. Our findings suggest that the capability approach provides a framework that is able to capture the educational experiences–outcomes journey of the young women. However, also interesting to note is how the expansion of their capabilities is bounded, primarily because their freedoms are intrinsically linked to their sociocultural positioning and largely negative perceptions of disability in the wider society.This is the author accepted manuscript. The final version is available from Taylor & Francis at http://dx.doi.org/10.1080/13603116.2015.104396

Prostaglandin D2 inhibits airway dendritic cell migration and function in steady state conditions by selective activation of the D prostanoid receptor 1

PGD(2) is the major mediator released by mast cells during allergic responses, and it acts through two different receptors, the D prostanoid receptor 1 (DP1) and DP2, also known as CRTH2. Recently, it has been shown that PGD(2) inhibits the migration of epidermal Langerhans cells to the skin draining lymph nodes (LNs) and affects the subsequent cutaneous inflammatory reaction. However, the role of PGD(2) in the pulmonary immune response remains unclear. Here, we show that the intratracheal instillation of FITC-OVA together with PGD(2) inhibits the migration of FITC(+) lung DC to draining LNs. This process is mimicked by the DP1 agonist BW245C, but not by the DP2 agonist DK-PGD(2). The ligation of DP1 inhibits the migration of FITC-OVA(+) DCs only temporarily, but still inhibits the proliferation of adoptively transferred, OVA-specific, CFSE-labeled, naive T cells in draining LNs. These T cells produced lower amounts of the T cell cytokines IL-4, IL-10, and IFN-gamma compared with T cells from mice that received FITC-OVA alone. Taken together, our data suggest that the activation of DP receptor by PGD(2) may represent a pathway to control airway DC migration and to limit the activation of T cells in the LNs under steady state conditions, possibly contributing to homeostasis in th

Erratum to: An Entropy Functional for Riemann-Cartan Space-Times

We correct the entropy functional constructed in Int. J. Theor. Phys. 51:362 (2012). The 'on-shell' functional one obtains from this correct functional possesses a holographic structure without imposing any constraint on the spin-angular momentum tensor of matter, in contrast to the conclusion made in the above paper.Comment: 15 pages. These are the preprints of the original paper and its erratum published in Int. J. Theor. Phy

Penerapan Media Film Untuk Meningkatkan Hasil Belajar Siswa Pada Mata Pelajaran IPS Terpadu Kelas VII SMP Negeri 10 Kota Banda Aceh

Istilah media berasal dari kata latin yang merupakan bentuk kata medium yang berarti perantara atau pengantar pesan. Media film merupakan media yang dipergunakan untuk memvisualisasikan atau menyalurkan pesan dari sumber ke penerima. Penelitian ini bertujuan untuk mengetahui: (1) Peningkatan hasil belajar Peserta didik; (2) Kegiatan guru dan Peserta didik; (3) Keterampilan guru dalam mengelola pembelajaran dan (4) Respon siswa terhadap penerapan media film. Subjek pada penelitian ini adalah peserta didik kelas VII SMPN 10 Banda Aceh yaitu 25 orang. Materi pembelajaran dalam penelitian ini adalah potensi dan pemanfaatan sumber daya alam. Hasil penelitian membuktikan bahwa (1) Persentase ketuntasan individual mengalami peningkatan dari 19 siswa yang tuntas pada siklus I, 22 pada siklus II dan 24 tuntas pada siklus III, persentase ketuntasan klasikal meningkat dari 60% di siklus I, 80% di siklus II dan 90% di siklus III; (2) Kegiatan guru dan peserta didik meningkat dari siklus I hingga siklus III, pada siklus I dari 8 aktivitas 3 aktivitas yang belum tuntas, 2 aktivitas pada siklus II, dan pada siklus ke III semuanya sudah tuntas; (3) Keterampilan guru meningkat dari perolehan skor 2,55 pada siklus I berkategori sedang, skor 2,66 di siklus II berkategori baik dan 3,49 di siklus III dengan berkategori baik; (4) Respon siswa terhadap penerapan media film bisa dikategorikan baik yaitu 96 persen

Two loop electroweak corrections to Bˉ→Xsγ\bar B\rightarrow X_s\gamma and Bs0→μ+μ−B_s^0\rightarrow \mu^+\mu^- in the B-LSSM

The rare decays $\bar B\rightarrow X_s\gamma$ and $B_s^0\rightarrow \mu^+\mu^-$ are important to research new physics beyond standard model. In this work, we investigate two loop electroweak corrections to $\bar B\rightarrow X_s\gamma$ and $B_s^0\rightarrow \mu^+\mu^-$ in the minimal supersymmetric extension of the SM with local $B-L$ gauge symmetry (B-LSSM), under a minimal flavor violating assumption for the soft breaking terms. In this framework, new particles and new definition of squarks can affect the theoretical predictions of these two processes, with respect to the MSSM. Considering the constraints from updated experimental data, the numerical results show that the B-LSSM can fit the experimental data for the branching ratios of $\bar B\rightarrow X_s\gamma$ and $B_s^0\rightarrow \mu^+\mu^-$. The results of the rare decays also further constrain the parameter space of the B-LSSM.Comment: 33 pages, 9 figures, Published in EPJ

Population-level impact and herd effects following the introduction of human papillomavirus vaccination programmes: updated systematic review and meta-analysis

Background More than 10 years have elapsed since human papillomavirus (HPV) vaccination was implemented. We did a systematic review and meta-analysis of the population-level impact of vaccinating girls and women against human papillomavirus on HPV infections, anogenital wart diagnoses, and cervical intraepithelial neoplasia grade 2+ (CIN2+)to summarise the most recent evidence about the effectiveness of HPV vaccines in real-world settings and to quantify the impact of multiple age-cohort vaccination.Methods In this updated systematic review and meta-analysis, we used the same search strategy as in our previous paper. We searched MEDLINE and Embase for studies published between Feb 1, 2014, and Oct 11, 2018. Studies were eligible if they compared the frequency (prevalence or incidence) of at least one HPV-related endpoint (genital HPV infections, anogenital wart diagnoses, or histologically confirmed CIN2+) between pre-vaccination and post-vaccination periods among the general population and if they used the same population sources and recruitment methods before and after vaccination. Our primary assessment was the relative risk (RR) comparing the frequency (prevalence or incidence) of HPV-related endpoints between the pre-vaccination and post-vaccination periods. We stratified all analyses by sex, age, and years since introduction of HPV vaccination. We used random-effects models to estimate pooled relative risks.Findings We identified 1702 potentially eligible articles for this systematic review and meta-analysis, and included 65 articles in 14 high-income countries: 23 for HPV infection, 29 for anogenital warts, and 13 for CIN2+.After 5\u20138 years of vaccination, the prevalence of HPV 16 and 18 decreased significantly by 83% (RR 0\ub717, 95% CI 0\ub711\u20130\ub725) among girls aged 13\u201319 years, and decreased significantly by 66% (RR 0\ub734, 95% CI 0\ub723\u20130\ub749) among women aged 20\u201324 years. The prevalence of HPV 31, 33, and 45 decreased significantly by 54% (RR 0\ub746, 95% CI 0\ub733\u20130\ub766) among girls aged 13\u201319 years. Anogenital wart diagnoses decreased significantly by 67% (RR 0\ub733, 95% CI 0\ub724\u20130\ub746) among girls aged 15\u201319 years, decreased significantly by 54% (RR 0\ub746, 95% CI 0.36\u20130.60) among women aged 20\u201324 years, and decreased significantly by 31% (RR 0\ub769, 95% CI 0\ub753\u20130\ub789) among women aged 25\u201329 years. Among boys aged 15\u201319 years anogenital wart diagnoses decreased significantly by 48% (RR 0\ub752, 95% CI 0\ub737\u20130\ub775) and among men aged 20\u201324 years they decreased significantly by 32% (RR 0\ub768, 95% CI 0\ub747\u20130\ub798). After 5\u20139 years of vaccination, CIN2+ decreased significantly by 51% (RR 0\ub749, 95% CI 0\ub742\u20130\ub758) among screened girls aged 15\u201319 years and decreased significantly by 31% (RR 0\ub769, 95% CI 0\ub757\u20130\ub784) among women aged 20\u201324 years.Interpretation This updated systematic review and meta-analysis includes data from 60 million individuals and up to 8 years of post-vaccination follow-up. Our results show compelling evidence of the substantial impact of HPV vaccination programmes on HPV infections and CIN2+ among girls and women, and on anogenital warts diagnoses among girls, women, boys, and men. Additionally, programmes with multi-cohort vaccination and high vaccination coverage had a greater direct impact and herd effects

Towards Assessing the Vernacular in the Arabic Language: A Descriptive Analytical Study

This research aims to highlight the nature of vernacular in the Arabic language, reasons for their emergence, their importance and natural role. It seeks to achieve a balanced relationship between vernacular and the standard language in a scholarly and objective manner. Vernacular is not an undesirable phenomenon people should seek to treat. It is rather a practice Allah prescribed to humankind, a natural human phenomenon that cannot be eradicated. We shall keep pace and coexist with it. Vernaculars play an obvious humanitarian role; they perform social mission in their own environments. A standard language cannot supersede the vernacular. This is conditioned on that vernaculars should play their role in their own fields. A standard language enjoys a status, role and platforms, which cannot be shared with vernacular. Their relation remains complementary

Search for the standard model Higgs boson in the H to ZZ to 2l 2nu channel in pp collisions at sqrt(s) = 7 TeV

A search for the standard model Higgs boson in the H to ZZ to 2l 2nu decay channel, where l = e or mu, in pp collisions at a center-of-mass energy of 7 TeV is presented. The data were collected at the LHC, with the CMS detector, and correspond to an integrated luminosity of 4.6 inverse femtobarns. No significant excess is observed above the background expectation, and upper limits are set on the Higgs boson production cross section. The presence of the standard model Higgs boson with a mass in the 270-440 GeV range is excluded at 95% confidence level.Comment: Submitted to JHE

Combined search for the quarks of a sequential fourth generation

Results are presented from a search for a fourth generation of quarks produced singly or in pairs in a data set corresponding to an integrated luminosity of 5 inverse femtobarns recorded by the CMS experiment at the LHC in 2011. A novel strategy has been developed for a combined search for quarks of the up and down type in decay channels with at least one isolated muon or electron. Limits on the mass of the fourth-generation quarks and the relevant Cabibbo-Kobayashi-Maskawa matrix elements are derived in the context of a simple extension of the standard model with a sequential fourth generation of fermions. The existence of mass-degenerate fourth-generation quarks with masses below 685 GeV is excluded at 95% confidence level for minimal off-diagonal mixing between the third- and the fourth-generation quarks. With a mass difference of 25 GeV between the quark masses, the obtained limit on the masses of the fourth-generation quarks shifts by about +/- 20 GeV. These results significantly reduce the allowed parameter space for a fourth generation of fermions.Comment: Replaced with published version. Added journal reference and DO