838 research outputs found
Sociocultural Contexts of HIV Transmission for Newcomer Black Gay, Bisexual Men (GBM) Who Have Sex with Men: Implications for Sexual Health Education and Human Rights in Ontario, Canada
This article examines the sociocultural and structural conditions that shape HIV vulnerability among newcomer Black gay, bisexual, and other men who have sex with men (GBM) in Ontario, Canada. Based on qualitative data from focus groups with 22 newcomer Black GBM, the study explores how intersecting experiences of anti-Black racism, homophobia, trauma, and precarity during migration and resettlement impact access to sexual health education and care. Participants shared accounts of violence in their countries of origin, challenges navigating Canada’s housing and healthcare systems, and the ongoing mental health impacts of displacement and marginalization. Using a community-based participatory research framework, and in partnership with the Black Coalition for AIDS Prevention (Black CAP), the article argues for a culturally responsive and rights-based approach to sexual health education—one that centres the lived realities of Black GBM newcomers. The findings underscore the urgency of trauma-informed, anti-racist, and inclusive services to support HIV prevention, mental health, and human rights for this underserved population
The 74MHz System on the Very Large Array
The Naval Research Laboratory and the National Radio Astronomy Observatory
completed implementation of a low frequency capability on the VLA at 73.8 MHz
in 1998. This frequency band offers unprecedented sensitivity (~25 mJy/beam)
and resolution (~25 arcsec) for low-frequency observations. We review the
hardware, the calibration and imaging strategies, comparing them to those at
higher frequencies, including aspects of interference excision and wide-field
imaging. Ionospheric phase fluctuations pose the major difficulty in
calibrating the array. Over restricted fields of view or at times of extremely
quiescent ionospheric ``weather'', an angle-invariant calibration strategy can
be used. In this approach a single phase correction is devised for each
antenna, typically via self-calibration. Over larger fields of view or at times
of more normal ionospheric ``weather'' when the ionospheric isoplanatic patch
size is smaller than the field of view, we adopt a field-based strategy in
which the phase correction depends upon location within the field of view. This
second calibration strategy was implemented by modeling the ionosphere above
the array using Zernike polynomials. Images of 3C sources of moderate strength
are provided as examples of routine, angle-invariant calibration and imaging.
Flux density measurements indicate that the 74 MHz flux scale at the VLA is
stable to a few percent, and tied to the Baars et al. value of Cygnus A at the
5 percent level. We also present an example of a wide-field image, devoid of
bright objects and containing hundreds of weaker sources, constructed from the
field-based calibration. We close with a summary of lessons the 74 MHz system
offers as a model for new and developing low-frequency telescopes. (Abridged)Comment: 73 pages, 46 jpeg figures, to appear in ApJ
Processing factors affecting the quality of pheasant meat
Call number: LD2668 .T4 1968 M325Master of Scienc
Two-layer viscous instability in a rotating couette device
A novel experiment to study the interfacial shear instability between two liquids is described. Density-matched immiscible liquids are confined between concentric cylinders such that the interface is parallel to the cylinder walls. Interfacial waves that develop because of viscosity differences between the shearing fluids are studied as a function of rotation rate and depth ratio using optical techniques. Conditions neutral stability and the most unstable wavenumber agree reasonably well with predictions from linear stability analysis of the Navier-Stokes equations. Illumination using laser sheets allows precise measurement of the interface shape. Future experiments will verify the correctness of weakly nonlinear theories that describe energy transfer and saturation of wave growth by nonlinear effects. Measurements of solitary wave shapes, that occur far above neutral stability, will be compared to similar measurements for systems that have gravity as an important force to determine how gravity effects large disturbances. These results will be used to interpret slug and annular flow data that have been obtained in other mu g studies
Fundamental Processes of Atomization in Fluid-Fluid Flows
This paper discusses our proposed experimental and theoretical study of atomization in gas-liquid and liquid-liquid flows. While atomization is a very important process in these flows, the fundamental mechanism is not understood and there is no predictive theory. Previous photographic studies in (turbulent) gas-liquid flows have shown that liquid is atomized when it is removed by the gas flow from the crest of large solitary or roll waves. Our preliminary studies in liquid-liquid laminar flows exhibit the same mechanism. The two-liquid system is easier to study than gas-liquid systems because the time scales are much slower, the length scales much larger, and there is no turbulence. The proposed work is intended to obtain information about the mechanism of formation, rate of occurrence and the evolving shape of solitary waves; and quantitative aspects of the detailed events of the liquid removal process that can be used to verify a general predictive theory
Onset of the aerobic nitrogen cycle during the Great Oxidation Event
The rise of oxygen on the early Earth (about 2.4 billion years ago)1 caused a reorganization of marine nutrient cycles2, 3, including that of nitrogen, which is important for controlling global primary productivity. However, current geochemical records4 lack the temporal resolution to address the nature and timing of the biogeochemical response to oxygenation directly. Here we couple records of ocean redox chemistry with nitrogen isotope (15N/14N) values from approximately 2.31-billion-year-old shales5 of the Rooihoogte and Timeball Hill formations in South Africa, deposited during the early stages of the first rise in atmospheric oxygen on the Earth (the Great Oxidation Event)6. Our data fill a gap of about 400 million years in the temporal 15N/14N record4 and provide evidence for the emergence of a pervasive aerobic marine nitrogen cycle. The interpretation of our nitrogen isotope data in the context of iron speciation and carbon isotope data suggests biogeochemical cycling across a dynamic redox boundary, with primary productivity fuelled by chemoautotrophic production and a nitrogen cycle dominated by nitrogen loss processes using newly available marine oxidants. This chemostratigraphic trend constrains the onset of widespread nitrate availability associated with ocean oxygenation. The rise of marine nitrate could have allowed for the rapid diversification and proliferation of nitrate-using cyanobacteria and, potentially, eukaryotic phytoplankton
International longitudinal registry of patients with atrial fibrillation and treated with rivaroxaban: RIVaroxaban Evaluation in Real life setting (RIVER)
Background
Real-world data on non-vitamin K oral anticoagulants (NOACs) are essential in determining whether evidence from randomised controlled clinical trials translate into meaningful clinical benefits for patients in everyday practice. RIVER (RIVaroxaban Evaluation in Real life setting) is an ongoing international, prospective registry of patients with newly diagnosed non-valvular atrial fibrillation (NVAF) and at least one investigator-determined risk factor for stroke who received rivaroxaban as an initial treatment for the prevention of thromboembolic stroke. The aim of this paper is to describe the design of the RIVER registry and baseline characteristics of patients with newly diagnosed NVAF who received rivaroxaban as an initial treatment.
Methods and results
Between January 2014 and June 2017, RIVER investigators recruited 5072 patients at 309 centres in 17 countries. The aim was to enroll consecutive patients at sites where rivaroxaban was already routinely prescribed for stroke prevention. Each patient is being followed up prospectively for a minimum of 2-years. The registry will capture data on the rate and nature of all thromboembolic events (stroke / systemic embolism), bleeding complications, all-cause mortality and other major cardiovascular events as they occur. Data quality is assured through a combination of remote electronic monitoring and onsite monitoring (including source data verification in 10% of cases). Patients were mostly enrolled by cardiologists (n = 3776, 74.6%), by internal medicine specialists 14.2% (n = 718) and by primary care/general practice physicians 8.2% (n = 417). The mean (SD) age of the population was 69.5 (11.0) years, 44.3% were women. Mean (SD) CHADS2 score was 1.9 (1.2) and CHA2DS2-VASc scores was 3.2 (1.6). Almost all patients (98.5%) were prescribed with once daily dose of rivaroxaban, most commonly 20 mg (76.5%) and 15 mg (20.0%) as their initial treatment; 17.9% of patients received concomitant antiplatelet therapy. Most patients enrolled in RIVER met the recommended threshold for AC therapy (86.6% for 2012 ESC Guidelines, and 79.8% of patients according to 2016 ESC Guidelines).
Conclusions
The RIVER prospective registry will expand our knowledge of how rivaroxaban is prescribed in everyday practice and whether evidence from clinical trials can be translated to the broader cross-section of patients in the real world
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