Indonesia Herbal Medicine and Its Active Compounds for Anti-diabetic Treatment: A Systematic Mini Review

We reported the systematic review of anti-diabetic herbal medicine from Indonesia by integrating herbal medicine databases and summarized the anti-diabetic compounds in Indonesian plants. We used data sources from Pubmed and local Indonesian databases such as Portal Garuda and Basis Data Tanaman Obat Indonesia (BDTOI) to elucidate anti-diabetic candidate herbal medicine. We found 927 articles (PubMed) and 70 articles (Portal Garuda) based on the criteria of anti-diabetic properties. After thoroughly assessing those publications, 38 articles on controlling blood glucose were identified. Moreover, we utilized ClinicalTrial.gov to map the evidence. Five species (Abelmoschus esculentus, Allium sativum L, Cinnamomum cassia, Citrullus colocynthis, and Punica granatum L) passed the clinical trial, three of which were intended for use in treating other diseases, and eight of which lacked clinical evidence. Additionally, over 30 compounds were elucidating from those herbs, including quercetin and allicin. In conclusion, we successfully retrieved anti-diabetic herbal medicine from Indonesia by integrating public databases. The molecular docking study was employed to predict and optimize the anti-diabetic outcomes

Elastic stability of curved nanobeam based on higher-order shear deformation theory and nonlocal analysis by finite element approach

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Vibration study of curved nanobeams based on nonlocal higher-order shear deformation theory using finite element approach

International audienc

A nonlocal higher-order curved beam finite model including thickness stretching effect for bending analysis of curved nanobeams

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Nonlinear Dynamic Thermal Buckling of Sandwich Spherical and Conical Shells with CNT Reinforced Facesheets

Owing to their superior mechanical and thermal properties, carbon nanotube (CNT) reinforced composite materials have wide range of applications in various technical areas such as aerospace, automobile, chemical, structural and energy. In this paper, the nonlinear axisymmetric dynamic behavior of sandwich spherical and conical shells made up of CNT reinforced facesheets is studied. The shell is subjected to thermal loads and discretized with three-noded axisymmetric curved shell element based on field consistency approach. The in-plane and the rotary inertia effects are included within the transverse shear deformation theory in the element formulation. The present model is validated with the available analytical solutions from the literature. A detailed parametric study is carried out to showcase the effects of the shell geometry, the volume fraction of the CNT, the core-to-face sheet thickness and the environment temperature on the dynamic buckling thermal load of spherical caps.</jats:p

Adaptive navigation of an omni-drive autonomous mobile robot in unstructured dynamic environments

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