1,383 research outputs found

    The Predictive Utility Of Drinking Refusal Self-Efficacy And Alcohol Expectancy: A Diary-Based Study Of Tension Reduction

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    The potential tension reduction effects of alcohol may be most appropriately tested by examining the role of alcohol related beliefs regarding alcohol's anxiolytic properties. The relationship between affective change drinking refusal self-efficacy, tension reduction alcohol expectancies, and ongoing drinking behavior was examined amongst 57 regular drinkers. Alcohol consumption, antecedent, and consequent mood states were monitored prospectively by diary. Social leaming theory hypothesizes that low drinking refusal self-efficacy when experiencing a negative mood state should be associated with more frequent drinking when tense. Strong alcohol expectancies of tension reduction were hypothesized to predict subsequent tension reduction. Contrary to this hypothesis, the present study found that alcohol expectancies were more strongly related to antecedent mood states. Only a weak relationship between drinking refusal self-efficacy and predrinking tension, and between alcohol expectancy and subsequent tension reduction, was evident

    The Psychobiological Correlates Of Panic Attacks During In Vivo Exposure

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    This study examined in detail the psychobiological correlates of panic attacks experienced in panic disorder with agoraphobia. The cognitions, affect, and physiology of the six patients were monitored during in vivo exposure to their phobic situations. The results from these case studies showed that catastrophic cognitions are the key component of panic attacks. However, there was no clear-cut evidence to support an interaction among cognitions, affect, and physiology, which has been postulated by cognitive theories to be the central component of panic attacks and panic disorder with agoraphobia

    Touching points of s star-shaped set with an affine subspace

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    AbstractThe paper studies the following problem. Given a linear subspace L ⊂ Rn of dimension k, 1 ⩽ k ⩽ n – 1, the point x ∃ Rn, x ∉ L, and a star-shaped set A ⊂ Rn, characterize those τ> 0 for which L + x touches τA, and, if this is the case, describe the set τ cl(A)∩(L + x). Here A is star-shaped if λA ⊆ A for all 0 ⩽ λ ⩽ 1, L + x touches τA if L + x meets τA only on the boundary, and cl(A) means the closure of A. The problem is solved for two kinds of sets: convex A such that the origin θ is contained in the relative interior of A, and A equals to the closed unit ɭp-ball Gp for some 0 < p < 1. For convex A the set L⊥ ∩ A∗ plays a crucial role, where A∗ ≔ {z ∃ Rn:⇄z,y↩ ⩽ 1 for all y ∈ A} is the polar of A, and L⊊ is the orthogonal complement subspace to L. For Gp the problem is solved by a special geometrical construction based on “coordinate” subspaces RT such that L ∩ RT = {θ}

    Pengaruh Kualitas Layanan Dan Kualitas Produk Terhadap Kepuasan Konsumen Di the Carpentier Surabaya

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    Penelitian ini dilakukan untuk menganalisa pengaruh kualitas layanan dan kualitas produk terhadap kepuasan konsumen dan mengukur dampak manakah yang lebih besar pengaruhnya antara kualitas layanan atau kualitas produk terhadap kepuasan konsumen.Teknik analisa yang digunakan adalah deskriptif kuantitatif, regresi linier berganda. Hasil penelitian menunjukkan bahwa kualitas layanan dan kualitas produk berpengaruh positif dan signifikan terhadap kepuasan konsumen di The Carpentier

    Indium phosphide based membrane photodetector for optical interconnects on silicon

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    We have designed, fabricated and characterized an InP-based membrane photodetector on an SOI wafer containing a Si-wiring photonic circuit. New results on RF characterization up to 20 GHz are presented. The detector fabrication is compatible with wafer scale processing steps, guaranteeing compatibility towards future generation electronic IC processing

    InP/InGaAs photodetector on SOI photonic circuitry

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    We present an InP-based membrane p-i-n photodetector on a silicon-on-insulator sample containing a Si-wiring photonic circuit that is suitable for use in optical interconnections on Si integrated circuits (ICs). The detector mesa footprint is 50 mu m(2), which is the smallest reported to date for this kind of device, and the junction capacitance is below 10 fF, which allows for high integration density and low dynamic power consumption. The measured detector responsivity and 3-dB bandwidth are 0.45 A/W and 33 GHz, respectively. The device fabrication is compatible with wafer-scale processing steps, guaranteeing compatibility toward future-generation electronic IC processing

    Enrichment analysis of Alu elements with different spatial chromatin proximity in the human genome

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    Transposable elements (TEs) have no longer been totally considered as “junk DNA” for quite a time since the continual discoveries of their multifunctional roles in eukaryote genomes. As one of the most important and abundant TEs that still active in human genome, Alu, a SINE family, has demonstrated its indispensable regulatory functions at sequence level, but its spatial roles are still unclear. Technologies based on 3C(chromosomeconformation capture) have revealed the mysterious three-dimensional structure of chromatin, and make it possible to study the distal chromatin interaction in the genome. To find the role TE playing in distal regulation in human genome, we compiled the new released Hi-C data, TE annotation, histone marker annotations, and the genome-wide methylation data to operate correlation analysis, and found that the density of Alu elements showed a strong positive correlation with the level of chromatin interactions (hESC: r=0.9, P<2.2×1016; IMR90 fibroblasts: r = 0.94, P < 2.2 × 1016) and also have a significant positive correlation withsomeremote functional DNA elements like enhancers and promoters (Enhancer: hESC: r=0.997, P=2.3×10−4; IMR90: r=0.934, P=2×10−2; Promoter: hESC: r = 0.995, P = 3.8 × 10−4; IMR90: r = 0.996, P = 3.2 × 10−4). Further investigation involving GC content and methylation status showed the GC content of Alu covered sequences shared a similar pattern with that of the overall sequence, suggesting that Alu elements also function as the GC nucleotide and CpG site provider. In all, our results suggest that the Alu elements may act as an alternative parameter to evaluate the Hi-C data, which is confirmed by the correlation analysis of Alu elements and histone markers. Moreover, the GC-rich Alu sequence can bring high GC content and methylation flexibility to the regions with more distal chromatin contact, regulating the transcription of tissue-specific genes

    ICON 2019: International Scientific Tendinopathy Symposium Consensus: Clinical Terminology

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    © Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ.Background Persistent tendon pain that impairs function has inconsistent medical terms that can influence choice of treatment.1 When a person is told they have tendinopathy by clinician A or tendinitis by clinician B, they might feel confused or be alarmed at receiving what they might perceive as two different diagnoses. This may lead to loss of confidence in their health professional and likely adds to uncertainty if they were to search for information about their condition. Clear and uniform terminology also assists inter-professional communication. Inconsistency in terminology for painful tendon disorders is a problem at numerous anatomical sites. Historically, the term ‘tendinitis’ was first used to describe tendon pain, thickening and impaired function (online supplementary figure S1). The term ‘tendinosis’ has also been used in a small number of publications, some of which were very influential.2 3 Subsequently, ‘tendinopathy’ emerged as the most common term for persistent tendon pain.4 5 To our knowledge, experts (clinicians and researchers) or patients have never engaged in a formal process to discuss the terminology we use. We believe that health professionals have not yet agreed on the appropriate terminology for painful tendon conditions.Peer reviewedFinal Accepted Versio

    Effectiveness of a self-help cognitive behavioural treatment program for problem gamblers: a randomised controlled trial

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    The study aimed to strengthen the scarce literature on self-help treatments for Problem Gambling (PG) by comparing the effectiveness of a Self-Help Cognitive Behavioral Treatment (SHCBT) program (n\ua0=\ua023) with a 6-week Waitlist condition (n\ua0=\ua032) in problem gamblers. Participants were community volunteers with gambling problems and were randomly allocated to the Waitlist and treatment conditions. Results showed significant improvements at post-treatment in gambling behaviors including frequency of gambling, average amount gambled per day and PG symptoms as well as a number of gambling correlates including psychological states (e.g., depression, anxiety and stress), gambling cognitions, gambling urges, gambling related self-efficacy, satisfaction with life, and quality of life among those who completed the SHCBT program, when compared with the waitlist condition. The effect size (partial η) ranged from .25 to .57 for all assessed outcomes that showed significant improvement from pre- to post-treatment. It was concluded that a self-help CBT program can be beneficial for treating community problem gamblers
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