Large Area Crop Inventory Experiment (LACIE). The boundary pixel study in Kansas and North Dakota

The author has identified the following significant results. The statistical mapping approach to handling boundary pixels can be used as a standard for objectively comparing the cluster based technique, the maximum likelihood estimate based technique, and multicategory labeling

SAX J1808.4-3658, an accreting millisecond pulsar shining in gamma rays?

We report the detection of a possible gamma-ray counterpart of the accreting millisecond pulsar SAX J1808.4-3658. The analysis of ~6 years of data from the Large Area Telescope on board the Fermi Gamma-ray Space Telescope (Fermi-LAT) within a region of 15deg radius around the position of the pulsar reveals a point gamma-ray source detected at a significance of ~6 sigma (Test Statistic TS = 32), with position compatible with that of SAX J1808.4-3658 within 95% Confidence Level. The energy flux in the energy range between 0.6 GeV and 10 GeV amounts to (2.1 +- 0.5) x 10-12 erg cm-2 s-1 and the spectrum is well-represented by a power-law function with photon index 2.1 +- 0.1. We searched for significant variation of the flux at the spin frequency of the pulsar and for orbital modulation, taking into account the trials due to the uncertainties in the position, the orbital motion of the pulsar and the intrinsic evolution of the pulsar spin. No significant deviation from a constant flux at any time scale was found, preventing a firm identification via time variability. Nonetheless, the association of the LAT source as the gamma-ray counterpart of SAX J1808.4-3658 would match the emission expected from the millisecond pulsar, if it switches on as a rotation-powered source during X-ray quiescence.Comment: 8 pages, 4 figures, accepted by MNRA

Conservation of context-dependent splicing activity in distant Muscleblind homologs

The Muscleblind (MBL) protein family is a deeply conserved family of RNA binding proteins that regulate alternative splicing, alternative polyadenylation, RNA stability and RNA localization. Their inactivation due to sequestration by expanded CUG repeats causes symptoms in the neuromuscular disease myotonic dystrophy. MBL zinc fingers are the most highly conserved portion of these proteins, and directly interact with RNA. We identified putative MBL homologs in Ciona intestinalis and Trichoplax adhaerens, and investigated their ability, as well as that of MBL homologs from human/mouse, fly and worm, to regulate alternative splicing. We found that all homologs can regulate alternative splicing in mouse cells, with some regulating over 100 events. The cis-elements through which each homolog exerts its splicing activities are likely to be highly similar to mammalian Muscleblind-like proteins (MBNLs), as suggested by motif analyses and the ability of expanded CUG repeats to inactivate homolog-mediated splicing. While regulation of specific target exons by MBL/MBNL has not been broadly conserved across these species, genes enriched for MBL/MBNL binding sites in their introns may play roles in cell adhesion, ion transport and axon guidance, among other biological pathways, suggesting a specific, conserved role for these proteins across a broad range of metazoan species.National Institutes of Health (U.S.) (DP5 OD017865

Gamma-ray signatures of cosmic ray acceleration, propagation, and confinement in the era of CTA

Galactic cosmic rays are commonly believed to be accelerated at supernova remnants via diffusive shock acceleration. Despite the popularity of this idea, a conclusive proof for its validity is still missing. Gamma-ray astronomy provides us with a powerful tool to tackle this problem, because gamma rays are produced during cosmic ray interactions with the ambient gas. The detection of gamma rays from several supernova remnants is encouraging, but still does not constitute a proof of the scenario, the main problem being the difficulty in disentangling the hadronic and leptonic contributions to the emission. Once released by their sources, cosmic rays diffuse in the interstellar medium, and finally escape from the Galaxy. The diffuse gamma-ray emission from the Galactic disk, as well as the gamma-ray emission detected from a few galaxies is largely due to the interactions of cosmic rays in the interstellar medium. On much larger scales, cosmic rays are also expected to permeate the intracluster medium, since they can be confined and accumulated within clusters of galaxies for cosmological times. Thus, the detection of gamma rays from clusters of galaxies, or even upper limits on their emission, will allow us to constrain the cosmic ray output of the sources they contain, such as normal galaxies, AGNs, and cosmological shocks. In this paper, we describe the impact that the Cherenkov Telescope Array, a future ground-based facility for very-high energy gamma-ray astronomy, is expected to have in this field of research.Comment: accepted to Astroparticle Physics, special issue on Physics with the Cherenkov Telescope Arra

MAGIC upper limits on the very high energy emission from GRBs

The fast repositioning system of the MAGIC Telescope has allowed during its first data cycle, between 2005 and the beginning of year 2006, observing nine different GRBs as possible sources of very high energy gammas. These observations were triggered by alerts from Swift, HETE-II, and Integral; they started as fast as possible after the alerts and lasted for several minutes, with an energy threshold varying between 80 and 200 GeV, depending upon the zenith angle of the burst. No evidence for gamma signals was found, and upper limits for the flux were derived for all events, using the standard analysis chain of MAGIC. For the bursts with measured redshift, the upper limits are compatible with a power law extrapolation, when the intrinsic fluxes are evaluated taking into account the attenuation due to the scattering in the Metagalactic Radiation Field (MRF).Comment: 25 pages, 9 figures, final version accepted by ApJ. Changet title to "MAGIC upped limits on the VERY high energy emission from GRBs", re-organized chapter with description of observation, removed non necessaries figures, added plot of effective area depending on zenith angle, added an appendix explaining the upper limit calculation, added some reference

Discovery of VHE Gamma Radiation from IC443 with the MAGIC Telescope

We report the detection of a new source of very high energy (VHE, E_gamma >= 100GeV) gamma-ray emission located close to the Galactic Plane, MAGIC J0616+225, which is spatially coincident with SNR IC443. The observations were carried out with the MAGIC telescope in the periods December 2005 - January 2006 and December 2006 - January 2007. Here we present results from this source, leading to a VHE gamma-ray signal with a statistical significance of 5.7 sigma in the 2006/7 data and a measured differential gamma-ray flux consistent with a power law, described as dN_gamma/(dA dt dE) = (1.0 +/- 0.2)*10^(-11)(E/0.4 TeV)^(-3.1 +/- 0.3) cm^(-2)s^(-1)TeV^(-1). We briefly discuss the observational technique used and the procedure implemented for the data analysis. The results are put in the perspective of the multiwavelength emission and the molecular environment found in the region of IC443.Comment: Accepted by ApJ Letter

Constraints on the steady and pulsed very high energy gamma-ray emission from observations of PSR B1951+32/CTB 80 with the MAGIC Telescope

We report on very high energy gamma-observations with the MAGIC Telescope of the pulsar PSR B1951+32 and its associated nebula, CTB 80. Our data constrain the cutoff energy of the pulsar to be less than 32 GeV, assuming the pulsed gamma-ray emission to be exponentially cut off. The upper limit on the flux of pulsed gamma-ray emission above 75 GeV is 4.3*10^-11 photons cm^-2 sec^-1, and the upper limit on the flux of steady emission above 140 GeV is 1.5*10^-11 photons cm^-2 sec^-1. We discuss our results in the framework of recent model predictions and other studies.Comment: 7 pages, 7 figures, replaced with published versio

Observations of H1426+428 with HEGRA -- Observations in 2002 and reanalysis of 1999&2000 data

The HEGRA system of imaging air Cherenkov telescopes has been used to observe the BL Lac object H1426+428 ($z=0.129$) for 217.5 hours in 2002. In this data set alone, the source is detected at a confidence level of $5.3~\sigma$, confirming this object as a TeV source. The overall flux level during the observations in 2002 is found to be a factor of $\approx 2.5$ lower than during the previous observations by HEGRA in 1999&2000. A new spectral analysis has been carried out, improving the signal-to-noise ratio at the expense of a slightly increased systematic uncertainty and reducing the relative energy resolution to $\Delta E/E\le 12$ over a wide range of energies. The new method has also been applied to the previously published data set taken in 1999 and 2000, confirming the earlier claim of a flattening of the energy spectrum between 1 and 5 TeV. The data set taken in 2002 shows again a signal at energies above 1 TeV. We combine the energy spectra as determined by the CAT and VERITAS groups with our reanalyzed result of the 1999&2000 data set and apply a correction to account for effects of absorption of high energy photons on extragalactic background light in the optical to mid infrared band. The shape of the inferred source spectrum is mostly sensitive to the characteristics of the extragalactic background light between wavelengths of 1 and 15~$\mu$mComment: 12 pages, 4 Figures, submitted to A&