1,148 research outputs found
Clinical phenotype and contagiousness of early breakthrough SARS-CoV-2 infections after BNT162b2 COVID-19 mRNA vaccine: A parallel cohort study in healthcare workers
Multiwavelength observations of 3C 454.3 II. The AGILE 2007 December campaign
We report on the second AGILE multiwavelength campaign of the blazar 3C 454.3
during the first half of December 2007. This campaign involved AGILE, Spitzer,
Swift,Suzaku,the WEBT consortium,the REM and MITSuME telescopes,offering a
broad band coverage that allowed for a simultaneous sampling of the synchrotron
and inverse Compton (IC) emissions.The 2-week AGILE monitoring was accompanied
by radio to optical monitoring by WEBT and REM and by sparse observations in
mid-Infrared and soft/hard X-ray energy bands performed by means of Target of
Opportunity observations by Spitzer, Swift and Suzaku, respectively.The source
was detected with an average flux of~250x10^{-8}ph cm^-2s^-1 above 100
MeV,typical of its flaring states.The simultaneous optical and gamma-ray
monitoring allowed us to study the time-lag associated with the variability in
the two energy bands, resulting in a possible ~1-day delay of the gamma-ray
emission with respect to the optical one. From the simultaneous optical and
gamma-ray fast flare detected on December 12, we can constrain the delay
between the gamma-ray and optical emissions within 12 hours. Moreover, we
obtain three Spectral Energy Distributions (SEDs) with simultaneous data for
2007 December 5, 13, 15, characterized by the widest multifrequency coverage.
We found that a model with an external Compton on seed photons by a standard
disk and reprocessed by the Broad Line Regions does not describe in a
satisfactory way the SEDs of 2007 December 5, 13 and 15. An additional
contribution, possibly from the hot corona with T=10^6 K surrounding the jet,
is required to account simultaneously for the softness of the synchrotron and
the hardness of the inverse Compton emissions during those epochs.Comment: 13 pages, 8 figures, 2 tables, Accepted for publication in Ap
Multiwavelength Evidence for Quasi-periodic Modulation in the Gamma-ray Blazar PG 1553+113
We report for the first time a gamma-ray and multi-wavelength nearly-periodic
oscillation in an active galactic nucleus. Using the Fermi Large Area Telescope
(LAT) we have discovered an apparent quasi-periodicity in the gamma-ray flux (E
>100 MeV) from the GeV/TeV BL Lac object PG 1553+113. The marginal significance
of the 2.18 +/-0.08 year-period gamma-ray cycle is strengthened by correlated
oscillations observed in radio and optical fluxes, through data collected in
the OVRO, Tuorla, KAIT, and CSS monitoring programs and Swift UVOT. The optical
cycle appearing in ~10 years of data has a similar period, while the 15 GHz
oscillation is less regular than seen in the other bands. Further long-term
multi-wavelength monitoring of this blazar may discriminate among the possible
explanations for this quasi-periodicity.Comment: 8 pages, 5 figures. Accepted to The Astrophysical Journal Letters.
Corresponding authors: S. Ciprini (ASDC/INFN), S. Cutini (ASDC/INFN), S.
Larsson (Stockholm Univ/KTH), A. Stamerra (INAF/SNS), D. J. Thompson (NASA
GSFC
Investigating the peculiar emission from the new VHE gamma-ray source H1722+119
The MAGIC (Major Atmospheric Gamma-ray Imaging Cherenkov) telescopes observed
the BL Lac object H1722+119 (redshift unknown) for six consecutive nights
between 2013 May 17 and 22, for a total of 12.5 h. The observations were
triggered by high activity in the optical band measured by the KVA (Kungliga
Vetenskapsakademien) telescope. The source was for the first time detected in
the very high energy (VHE, GeV) -ray band with a statistical
significance of 5.9 . The integral flux above 150 GeV is estimated to
be per cent of the Crab Nebula flux. We used contemporaneous
high energy (HE, 100 MeV GeV) -ray observations from
Fermi-LAT (Large Area Telescope) to estimate the redshift of the source. Within
the framework of the current extragalactic background light models, we estimate
the redshift to be . Additionally, we used contemporaneous
X-ray to radio data collected by the instruments on board the Swift satellite,
the KVA, and the OVRO (Owens Valley Radio Observatory) telescope to study
multifrequency characteristics of the source. We found no significant temporal
variability of the flux in the HE and VHE bands. The flux in the optical and
radio wavebands, on the other hand, did vary with different patterns. The
spectral energy distribution (SED) of H1722+119 shows surprising behaviour in
the Hz frequency range. It can be modelled
using an inhomogeneous helical jet synchrotron self-Compton model.Comment: 12 pages, 5 figures, 2 table
Detection of very high energy gamma-ray emission from the gravitationally-lensed blazar QSO B0218+357 with the MAGIC telescopes
Context. QSO B0218+357 is a gravitationally lensed blazar located at a
redshift of 0.944. The gravitational lensing splits the emitted radiation into
two components, spatially indistinguishable by gamma-ray instruments, but
separated by a 10-12 day delay. In July 2014, QSO B0218+357 experienced a
violent flare observed by the Fermi-LAT and followed by the MAGIC telescopes.
Aims. The spectral energy distribution of QSO B0218+357 can give information on
the energetics of z ~ 1 very high energy gamma- ray sources. Moreover the
gamma-ray emission can also be used as a probe of the extragalactic background
light at z ~ 1. Methods. MAGIC performed observations of QSO B0218+357 during
the expected arrival time of the delayed component of the emission. The MAGIC
and Fermi-LAT observations were accompanied by quasi-simultaneous optical data
from the KVA telescope and X-ray observations by Swift-XRT. We construct a
multiwavelength spectral energy distribution of QSO B0218+357 and use it to
model the source. The GeV and sub-TeV data, obtained by Fermi-LAT and MAGIC,
are used to set constraints on the extragalactic background light. Results.
Very high energy gamma-ray emission was detected from the direction of QSO
B0218+357 by the MAGIC telescopes during the expected time of arrival of the
trailing component of the flare, making it the farthest very high energy
gamma-ray sources detected to date. The observed emission spans the energy
range from 65 to 175 GeV. The combined MAGIC and Fermi-LAT spectral energy
distribution of QSO B0218+357 is consistent with current extragalactic
background light models. The broad band emission can be modeled in the
framework of a two zone external Compton scenario, where the GeV emission comes
from an emission region in the jet, located outside the broad line region.Comment: 11 pages, 6 figures, accepted for publication in A&
Long-term multi-wavelength variability and correlation study of Markarian 421 from 2007 to 2009
We study the multi-band variability and correlations of the TeV blazar Mrk
421 on year time scales, which can bring additional insight on the processes
responsible for its broadband emission. We observed Mrk 421 in the very high
energy (VHE) gamma-ray range with the Cherenkov telescope MAGIC-I from March
2007 to June 2009 for a total of 96 hours of effective time after quality cuts.
The VHE flux variability is quantified with several methods, including the
Bayesian Block algorithm, which is applied to data from Cherenkov telescopes
for the first time. The 2.3 year long MAGIC light curve is complemented with
data from the Swift/BAT and RXTE/ASM satellites and the KVA, GASP-WEBT, OVRO,
and Mets\"ahovi telescopes from February 2007 to July 2009, allowing for an
excellent characterisation of the multi-band variability and correlations over
year time scales. Mrk 421 was found in different gamma-ray emission states
during the 2.3 year long observation period. Flares and different levels of
variability in the gamma-ray light curve could be identified with the Bayesian
Block algorithm. The same behaviour of a quiet and active emission was found in
the X-ray light curves measured by Swift/BAT and the RXTE/ASM, with a direct
correlation in time. The behaviour of the optical light curve of GASP-WEBT and
the radio light curves by OVRO and Mets\"ahovi are different as they show no
coincident features with the higher energetic light curves and a less variable
emission. The fractional variability is overall increasing with energy. The
comparable variability in the X-ray and VHE bands and their direct correlation
during both high- and low-activity periods spanning many months show that the
electron populations radiating the X-ray and gamma-ray photons are either the
same, as expected in the Synchrotron-Self-Compton mechanism, or at least
strongly correlated, as expected in electromagnetic cascades.Comment: Corresponding authors: Ann-Kristin Overkemping
([email protected]), Marina Manganaro
([email protected]), Diego Tescaro ([email protected]), To be published
in Astronomy&Astrophysics (A&A), 12 pages, 9 figure
First narrow-band search for continuous gravitational waves from known pulsars in advanced detector data
Spinning neutron stars asymmetric with respect to their rotation axis are potential sources of
continuous gravitational waves for ground-based interferometric detectors. In the case of known pulsars a
fully coherent search, based on matched filtering, which uses the position and rotational parameters
obtained from electromagnetic observations, can be carried out. Matched filtering maximizes the signalto-
noise (SNR) ratio, but a large sensitivity loss is expected in case of even a very small mismatch
between the assumed and the true signal parameters. For this reason, narrow-band analysis methods have
been developed, allowing a fully coherent search for gravitational waves from known pulsars over a
fraction of a hertz and several spin-down values. In this paper we describe a narrow-band search of
11 pulsars using data from Advanced LIGO’s first observing run. Although we have found several initial
outliers, further studies show no significant evidence for the presence of a gravitational wave signal.
Finally, we have placed upper limits on the signal strain amplitude lower than the spin-down limit for 5 of
the 11 targets over the bands searched; in the case of J1813-1749 the spin-down limit has been beaten for
the first time. For an additional 3 targets, the median upper limit across the search bands is below the
spin-down limit. This is the most sensitive narrow-band search for continuous gravitational waves carried
out so far
Impact of social determinants on antiretroviral therapy access and outcomes entering the era of universal treatment for people living with HIV in Italy
Background: Social determinants are known to be a driving force of health inequalities, even in high income countries. Aim of our study was to determine if these factors can limit antiretroviral therapy (ART) access, outcome and retention in care of people living with HIV (PLHIV) in Italy. Methods: All ART naïve HIV+ patients (pts) of Italian nationality enrolled in the ICONA Cohort from 2002 to 2016 were included. The association of socio-demographic characteristics (age, sex, risk factor for HIV infection, educational level, occupational status and residency area) with time to: ART initiation (from the first positive anti-HIV test), ART regimen discontinuation, and first HIV-RNA < 50 cp/mL, were evaluated by Cox regression analysis, Kaplan Meier method and log-rank test. Results: A total of 8023 HIV+ pts (82% males, median age at first pos anti-HIV test 36 years, IQR: 29-44) were included: 6214 (77.5%) started ART during the study period. Women, people who inject drugs (PWID) and residents in Southern Italy presented the lowest levels of education and the highest rate of unemployment compared to other groups. Females, pts aged > 50 yrs., unemployed vs employed, and people with lower educational levels presented the lowest CD4 count at ART initiation compared to other groups. The overall median time to ART initiation was 0.6 years (yrs) (IQR 0.1-3.7), with a significant decrease over time [2002-2006 = 3.3 yrs. (0.2-9.4); 2007-2011 = 1.0 yrs. (0.1-3.9); 2012-2016 = 0.2 yrs. (0.1-2.1), p < 0.001]. By multivariate analysis, females (p < 0.01) and PWID (p < 0.001), presented a longer time to ART initiation, while older people (p < 0.001), people with higher educational levels (p < 0.001), unemployed (p = 0.02) and students (p < 0.001) were more likely to initiate ART. Moreover, PWID, unemployed vs stable employed, and pts. with lower educational levels showed a lower 1-year probability of achieving HIV-RNA suppression, while females, older patients, men who have sex with men (MSM), unemployed had higher 1-year risk of first-line ART discontinuation. Conclusions: Despite median time to ART start decreased from 2002 to 2016, socio-demographic factors still contribute to disparities in ART initiation, outcome and durability
A search for spectral hysteresis and energy-dependent time lags from X-ray and TeV gamma-ray observations of Mrk 421
Blazars are variable emitters across all wavelengths over a wide range of
timescales, from months down to minutes. It is therefore essential to observe
blazars simultaneously at different wavelengths, especially in the X-ray and
gamma-ray bands, where the broadband spectral energy distributions usually
peak.
In this work, we report on three "target-of-opportunity" (ToO) observations
of Mrk 421, one of the brightest TeV blazars, triggered by a strong flaring
event at TeV energies in 2014. These observations feature long, continuous, and
simultaneous exposures with XMM-Newton (covering X-ray and optical/ultraviolet
bands) and VERITAS (covering TeV gamma-ray band), along with contemporaneous
observations from other gamma-ray facilities (MAGIC and Fermi-LAT) and a number
of radio and optical facilities. Although neither rapid flares nor significant
X-ray/TeV correlation are detected, these observations reveal subtle changes in
the X-ray spectrum of the source over the course of a few days. We search the
simultaneous X-ray and TeV data for spectral hysteresis patterns and time
delays, which could provide insight into the emission mechanisms and the source
properties (e.g. the radius of the emitting region, the strength of the
magnetic field, and related timescales). The observed broadband spectra are
consistent with a one-zone synchrotron self-Compton model. We find that the
power spectral density distribution at Hz from the
X-ray data can be described by a power-law model with an index value between
1.2 and 1.8, and do not find evidence for a steepening of the power spectral
index (often associated with a characteristic length scale) compared to the
previously reported values at lower frequencies.Comment: 45 pages, 15 figure
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