6,583 research outputs found
Icing Characteristics and Anti-Icing Heat Requirements for Hollow and Ternally Modified Gas-Heated Inlet Guide Vanes
A two-dimensional inlet-guide-vane cascade was investigated to determine the effects of ice formations on the pressure losses across the guide vanes and to evaluate the heated gas flow and temperature required to prevent Icing at various conditions. A gas flow of approximately 0.4 percent of the inlet-air flow was necessary for anti-icing a hollow guide-vane stage at an inlet-gas temperature of 500 F under the following icing conditions: air velocity, 280 miles per hour; water content, 0.9 gram per cubic meter; and Inlet-air static temperature, 00 F. Also presented are the anti-icing gas flows required with modifications of the hollow Internal gas passage, which show heatinput savings greater than 50 percent
Event-related brain potential correlates of human auditory sensory memory-trace formation
The event-related potential (ERP) component mismatch negativity (MMN) is a neural marker of human echoic memory. MMN is elicited by deviant sounds embedded in a stream of frequent standards, reflecting the deviation from an inferred memory trace of the standard stimulus. The strength of this memory trace is thought to be proportional to the number of repetitions of the standard tone, visible as the progressive enhancement of MMN with number of repetitions (MMN memory-trace effect). However, no direct ERP correlates of the formation of echoic memory traces are currently known. This study set out to investigate changes in ERPs to different numbers of repetitions of standards, delivered in a roving-stimulus paradigm in which the frequency of the standard stimulus changed randomly between stimulus trains. Normal healthy volunteers (n = 40) were engaged in two experimental conditions: during passive listening and while actively discriminating changes in tone frequency. As predicted, MMN increased with increasing number of standards. However, this MMN memory-trace effect was caused mainly by enhancement with stimulus repetition of a slow positive wave from 50 to 250 ms poststimulus in the standard ERP, which is termed here "repetition positivity" (RP). This RP was recorded from frontocentral electrodes when participants were passively listening to or actively discriminating changes in tone frequency. RP may represent a human ERP correlate of rapid and stimulus-specific adaptation, a candidate neuronal mechanism underlying sensory memory formation in the auditory cortex
Automated detection of asteroids in real-time with the Spacewatch telescope
The Spacewatch telescope on Kitt Peak is being used to survey for near-earth asteroids using a Tektronix TK2048 CCD in scanning mode. We hope to identify suitable low delta v candidates amongst the near-earth asteroid population as possible exploration targets, to identify those objects which pose a danger to life on earth, and to study the physical properties of the objects in near-earth space. Between Sep. 1990 and Jun. 1991, 14 new earth-approaching asteroids including 1 Aten, 9 Apollo, and 4 Amor type asteroids were detected by automated software and discriminated by their angular rates from the rest of the detected asteroids in near-real time by the observer. The average of about 1.5 earth-approaching asteroids per month is comparable to the total number found by all other observatories combined. One other Apollo type asteroid was detected by the observer as a long trailed image. The positions of this last object were measured and the object was tracked by the observer in real time. This object was determined to be a 5-10 meter diameter object which passed within 170,000 kilometers of earth. Of the 14 automatically detected earth-approaching asteroids, 10 have been found at distances in excess of 0.5 AU from earth. An average of more than 2000 asteroids are detected each month. Positions, angular rates, and brightnesses are determined for each of these asteroids in real-time
Maximum likelihood and pseudo score approaches for parametric time-to-event analysis with informative entry times
We develop a maximum likelihood estimating approach for time-to-event Weibull
regression models with outcome-dependent sampling, where sampling of subjects
is dependent on the residual fraction of the time left to developing the event
of interest. Additionally, we propose a two-stage approach which proceeds by
iteratively estimating, through a pseudo score, the Weibull parameters of
interest (i.e., the regression parameters) conditional on the inverse
probability of sampling weights; and then re-estimating these weights (given
the updated Weibull parameter estimates) through the profiled full likelihood.
With these two new methods, both the estimated sampling mechanism parameters
and the Weibull parameters are consistently estimated under correct
specification of the conditional referral distribution. Standard errors for the
regression parameters are obtained directly from inverting the observed
information matrix in the full likelihood specification and by either
calculating bootstrap or robust standard errors for the hybrid pseudo
score/profiled likelihood approach. Loss of efficiency with the latter approach
is considered. Robustness of the proposed methods to misspecification of the
referral mechanism and the time-to-event distribution is also briefly examined.
Further, we show how to extend our methods to the family of parametric
time-to-event distributions characterized by the generalized gamma
distribution. The motivation for these two approaches came from data on time to
cirrhosis from hepatitis C viral infection in patients referred to the
Edinburgh liver clinic. We analyze these data here.Comment: Published in at http://dx.doi.org/10.1214/14-AOAS725 the Annals of
Applied Statistics (http://www.imstat.org/aoas/) by the Institute of
Mathematical Statistics (http://www.imstat.org
Coherent coupling between surface plasmons and excitons in semiconductor nanocrystals
We present an experimental demonstration of strong coupling between a surface
plasmon propagating on a planar silver substrate, and the lowest excited state
of CdSe nanocrystals. Variable-angle spectroscopic ellipsometry measurements
demonstrated the formation of plasmon-exciton mixed states, characterized by a
Rabi splitting of 82 meV at room temperature. Such a coherent
interaction has the potential for the development of plasmonic non-linear
devices, and furthermore, this system is akin to those studied in cavity
quantum electrodynamics, thus offering the possibility to study the regime of
strong light-matter coupling in semiconductor nanocrystals at easily accessible
experimental conditions.Comment: 12 pages, 4 figure
Metagenomic sequencing unravels gene fragments with phylogenetic signatures of O2-tolerant NiFe membrane-bound hydrogenases in lacustrine sediment
Many promising hydrogen technologies utilising hydrogenase enzymes have been slowed by the fact that most hydrogenases are extremely sensitive to O2. Within the group 1 membrane-bound NiFe hydrogenase, naturally occurring tolerant enzymes do exist, and O2 tolerance has been largely attributed to changes in iron–sulphur clusters coordinated by different numbers of cysteine residues in the enzyme’s small subunit. Indeed, previous work has provided a robust phylogenetic signature of O2 tolerance [1], which when combined with new sequencing technologies makes bio prospecting in nature a far more viable endeavour. However, making sense of such a vast diversity is still challenging and could be simplified if known species with O2-tolerant enzymes were annotated with information on metabolism and natural environments. Here, we utilised a bioinformatics approach to compare O2-tolerant and sensitive membrane-bound NiFe hydrogenases from 177 bacterial species with fully sequenced genomes for differences in their taxonomy, O2 requirements, and natural environment. Following this, we interrogated a metagenome from lacustrine surface sediment for novel hydrogenases via high-throughput shotgun DNA sequencing using the Illumina™ MiSeq platform. We found 44 new NiFe group 1 membrane-bound hydrogenase sequence fragments, five of which segregated with the tolerant group on the phylogenetic tree of the enzyme’s small subunit, and four with the large subunit, indicating de novo O2-tolerant protein sequences that could help engineer more efficient hydrogenases
Assessment of the environmental toxicity and carcinogenicity of tungsten-based shot.
The toxicity of elemental tungsten released from discharged shot was assessed against previous studies that established a 1% toxic threshold for soil organisms. Extremely heavy theoretical shot loadings of 69,000 shot/ha were used to generate estimated environmental concentrations (EEC) for two brands of tungsten-based shot containing 51% and 95% tungsten. The corresponding tungsten EEC values were 6.5–13.5 mg W/kg soil, far below the 1% toxic threshold. The same shot loading in water produced tungsten EEC values of 2.1–4.4 mg W/L, levels that are not toxic under experimental conditions. Pure tungsten has not been shown to exhibit carcinogenic properties when ingested or embedded in animal tissues, but nickel, with which it is often alloyed, has known carcinogenicity. Given the large number of waterfowl that carry shot embedded in their body, it is advisable to screen lead shot substitutes for their carcinogenic potential through intra-muscular implantation
How useful is thematic analysis as an elicitation technique for analyzing video of human gait in forensic podiatry?
The aim of this study was to evaluate how useful thematic analysis is in the elicitation of observations of gait from a video recording. This was undertaken by providing a video recording of human gait to “novice” and “expert” podiatry students. The observations were explored using the qualitative tool of thematic analysis. The exploration of human gait using this technique gave a rich abundance of information and demonstrated that a basic level of experience or knowledge is required to provide a simple description of human gait. With more expertise came a richer description of observation of human gait by the “expert” group compared to basic observations by the “novice” group. Thematic analysis allows the use of language and the depth of the information to be evaluated when observing human gait from a video recording
Reduction of aqueous free chlorine with granular activated carbon
A surface reaction rate expression was developed to describe the heterogeneous reaction between aqueous free chlorine and granular activated carbon. This expression was then incorporated into a pore diffusion model and the relevant partial differential equations with the corresponding boundary conditions were solved for the case of (1) a constant concentration batch reactor and (2) a closed batch reactor. The solutions were then compared to similar batch data in order to evaluate the pore model constants. A packed bed reactor model was then solved using the rate information from the batch mathematical models and experimental data. The predicted results from the packed bed model were then compared to experimental results which were collected using applicable conditions. The effect of particle size on the rate of removal of free chlorine was investigated both in batch and packed bed column form. The effect of pH on the rate of reaction was studied in the pH range of 4-10. It was found that the pH only affects the rate insofar as it affects the distribution of free chlorine between OCl¯ and HOCl. Temperature effects were also studied in the range 2°-35°C. The effect of temperature on the surface dissociation rate constant was found to correspond to the Arrhenius law.U.S. Department of the InteriorU.S. Geological SurveyOpe
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