Changing preferences: an experiment and estimation of market-incentive effects on altruism

This paper studies how altruistic preferences are changed by markets and incentives. We conduct a laboratory experiment in a within-subject design. Subjects are asked to choose health care qualities for hypothetical patients in monopoly, duopoly, and quadropoly. Prices, costs, and patient benefits are experimental incentive parameters. In monopoly, subjects choose quality to tradeoff between profits and altruistic patient benefits. In duopoly and quadropoly, we model subjects playing a simultaneous-move game. Each subject is uncertain about an opponent's altruism, and competes for patients by choosing qualities. Bayes-Nash equilibria describe subjects' quality decisions as functions of altruism. Using a nonparametric method, we estimate the population altruism distributions from Bayes-Nash equilibrium qualities in different markets and incentive configurations. Markets tend to reduce altruism, although duopoly and quadropoly equilibrium qualities are much higher than those in monopoly. Although markets crowd out altruism, the disciplinary powers of market competition are stronger. Counterfactuals confirm markets change preferences.Accepted manuscrip

Evaluation of matrix-assisted laser desorption ionisation time-of-flight mass spectrometry (MALDI-TOF MS) for the Identification of Group B Streptococcus.

Objective Group B Streptococcus (GBS) is a leading cause of neonatal meningitis and sepsis worldwide. Intrapartum antibiotics given to women carrying GBS are an effective means of reducing disease in the first week of life. Rapid and reliable tests are needed to accurately identify GBS from these women for timely intrapartum antibiotic administration to prevent neonatal disease. Many laboratories now use matrix-assisted laser desorption ionisation time-of-flight mass spectrometry (MALDI-TOF MS) by direct plating or cell lysis for the identification of GBS isolates. The cell lysis step increases time to results for clinical samples and is more complex to perform. Therefore, we seek to evaluate the sensitivity and specificity of the quicker and more rapid direct plating method in identifying GBS. Results We directly compared swab isolates analysed by both direct plating and cell lysis method and demonstrated that direct plating has a sensitivity and specificity of 0.97 and 1, respectively, compared to an additional cell lysis step. We demonstrated that MALDI-TOF MS can be successfully used for batch processing by the direct plating method which saves time. These results are reassuring for laboratories worldwide who seek to identify GBS from swabs samples as quickly as possible

Phylogenetic Networks Do not Need to Be Complex: Using Fewer Reticulations to Represent Conflicting Clusters

Phylogenetic trees are widely used to display estimates of how groups of species evolved. Each phylogenetic tree can be seen as a collection of clusters, subgroups of the species that evolved from a common ancestor. When phylogenetic trees are obtained for several data sets (e.g. for different genes), then their clusters are often contradicting. Consequently, the set of all clusters of such a data set cannot be combined into a single phylogenetic tree. Phylogenetic networks are a generalization of phylogenetic trees that can be used to display more complex evolutionary histories, including reticulate events such as hybridizations, recombinations and horizontal gene transfers. Here we present the new CASS algorithm that can combine any set of clusters into a phylogenetic network. We show that the networks constructed by CASS are usually simpler than networks constructed by other available methods. Moreover, we show that CASS is guaranteed to produce a network with at most two reticulations per biconnected component, whenever such a network exists. We have implemented CASS and integrated it in the freely available Dendroscope software

Cryptographic applications of sparse polynomials over finite rings

This is a preprint of a book chapter published in Lecture Notes in Computer Science, 2015, Springer-Verlag, Berlin (2001). The original publication is available at www.springerlink.com.This paper gives new examples that exploit the idea of using sparse polynomials with restricted coefficients over a finite ring for designing fast, reliable cryptosystems and identification schemes

Transfert isolé des signaux de commande dans le contexte de l'intégration pour les composants actifs d'électronique de puissance

Cet article présente plusieurs solutions originales afin de réaliser un transfert isolé des ordres de commutation pour les semiconducteurs de puissance. Sous la contrainte de l'intégration aussi bien monolithique qu'hétérogène, trois solutions sont présentées de façons théoriques et expérimentales. Le premier mode de réalisation intégrée de l'isolation galvanique est une solution optique intégrée au composant de puissance et/ou au sein de son circuit de commande de type CMOS. Les performances statiques et dynamiques des récepteurs optiques sont tout à fait compatibles avec l'application. Enfin, plusieurs transformateurs sans noyau magnétique sont conçus, analysés et caractérisés via une réalisation CMOS, en prenant un soin particulier aux couplages hautes fréquences et éléments parasites. Ce circuit de transmission électromagnétique des ordres est intégré avec plusieurs fonctions de pilotages et le bon fonctionnement de l'ensemble du driver est démontré aussi bien pour les composants Haute Tension High Side que Low Side

Deagglomeration and mixing via the rapid expansion of high pressure and supercritical suspensions

Nano-materials are the focus of many research activities due to the desirable properties imparted from their small grain size and high interfacial surface area. However, these materials are highly cohesive powders in the dry state and typically form large agglomerates, leading to a diminished surface area or even grain growth, which minimizes the effectiveness of these nanomaterials. This dissertation addresses the issue of mixing nanopowders constituents by deagglomerating them and achieving simultaneous mixing so that even after inevitable reagglomeration, the effectiveness of large interfacial surface area may be preserved. Nano-particle mixtures were prepared using the environmentally benign dry mixing methods of Stirring in Supercritical Fluids and the Rapid Expansion of High Pressure and Supercritical Suspensions (REHPS). Stirring in Supercritical Fluids was capable of producing course scale nano-particle mixtures that were comparable to mixtures produced with more traditional liquid solvents, without the necessity of filtration and caking issues that are typically associated with them. The REHPS process was capable of producing high-quality mixtures on the sub-micron scale, and was made far superior when the nano-powders were first pre-mixed by stirring to decrease inhomogeneity of the feed. It was also shown that in general, conditions that enhanced turbulent shear stress, and thereby deagglomeration, also enhanced mixing, however this effect could be obscured by inhomogeneities introduced by the feed mixtures. Previous authors have suggested that the primary deagglomeration mechanism is the explosive expansion of the carbon dioxide from within the agglomerate as it transitions from a high pressure to an ambient environment. In this study two other deagglomeration mechanisms were proposed, namely intense turbulent shear stress imparted by the fluid in the nozzle and impaction with the Mach disc near the exit of the nozzle. Explosive expansion was observed to have almost no effect on nozzle deagglomeration and subsequent mixing. It has been shown that the turbulent shear stress and the residence time under shear were the dominant factors related to agglomerate breakage, while impaction with the Mach disc has played a minimal role

Do school crossing guards make crossing roads safer? A quasi-experimental study of pedestrian-motor vehicle collisions in Toronto, Canada

BACKGROUND: The presence of school crossing guards has been associated with more walking and more pedestrian-motor vehicle collisions (PMVCs) in area-level cross-sectional analyses. The objectives of the study were to (1) Determine the effect on PMVC rates of newly implemented crossing guards in Toronto, Canada (2) Determine where collisions were located in relation to crossing guards throughout the city, and whether they occurred during school travel times. METHODS: School crossing guards with 50 m buffers were mapped along with police-reported child PMVCs from 2000–2011. (1) A quasi-experimental study identified all age collision counts near newly implemented guards before and after implementation, modeled using repeated measures Poisson regression adjusted for season and built environment variables. (2) A retrospective cohort study of all child PMVCS throughout the city to determine the proportions of child PMVCs which occurred during school travel times and at guard locations. RESULTS: There were 27,827 PMVCs, with 260 PMVCs at the locations of 58 newly implemented guards. Repeated measures adjusted Poisson regression found PMVCs rates remained unchanged at guard locations after implementation (IRR 1.02, 95 % CI 0.74, 1.39). There were 568 guards citywide with 1850 child PMVCs that occurred at guard locations. The majority of child PMVCs occurred outside school travel times (n = 1155, 62 %) and of those that occurred during school travel times, only 95 (13.7 %) were at a guard location. CONCLUSIONS: School crossing guards are a simple roadway modification to increase walking to school without apparent detrimental safety effects. Other more permanent interventions are necessary to address the frequency of child PMVCs occurring away from the location of crossing guards, and outside of school travel times

Contributions aux circuits de « gate-driver » dédiés aux transistors de puissance à forte vitesse de commutation dans un environnement haute temperature

International audienceBasé sur les contraintes de fonctionnement des transistors à commutations rapides, cet article présente et analyse la problématique du transfert des ordres de commande du transistor « high-side » dans une configuration de bras d'onduleur. En plus des contraintes imposées par les forts « dv/dt » sur le driver, la température de fonctionnement élevée (jusqu'à 200°C) impose une conception spécifique du circuit de commande. Aujourd'hui, la technologie silicium reste la solution la plus fiable et la plus mature pour la conception du driver mais au prix d'une mise en œuvre délicate (tenue en tension, température, dv/dt). Trois solutions sont proposées et comparées : transformateur coreless, level-shifter et émetteur/récepteur optique. Les délais de propagation, l'intégrité du signal (durée du rapport cyclique et précision temporelle) ainsi que l'immunité aux dv/dt des prototypes sont caractérisées en fonction de la température ambiante de fonctionnement.</p

Predatory Bacteria: A Potential Ally against Multidrug-Resistant Gram-Negative Pathogens

Multidrug-resistant (MDR) Gram-negative bacteria have emerged as a serious threat to human and animal health. Bdellovibrio spp. and Micavibrio spp. are Gram-negative bacteria that prey on other Gram-negative bacteria. In this study, the ability of Bdellovibrio bacteriovorus and Micavibrio aeruginosavorus to prey on MDR Gram-negative clinical strains was examined. Although the potential use of predatory bacteria to attack MDR pathogens has been suggested, the data supporting these claims is lacking. By conducting predation experiments we have established that predatory bacteria have the capacity to attack clinical strains of a variety of ß-lactamase-producing, MDR Gram-negative bacteria. Our observations indicate that predatory bacteria maintained their ability to prey on MDR bacteria regardless of their antimicrobial resistance, hence, might be used as therapeutic agents where other antimicrobial drugs fail. © 2013 Kadouri et al