7,170 research outputs found

    On Identifying Disaster-Related Tweets: Matching-based or Learning-based?

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    Social media such as tweets are emerging as platforms contributing to situational awareness during disasters. Information shared on Twitter by both affected population (e.g., requesting assistance, warning) and those outside the impact zone (e.g., providing assistance) would help first responders, decision makers, and the public to understand the situation first-hand. Effective use of such information requires timely selection and analysis of tweets that are relevant to a particular disaster. Even though abundant tweets are promising as a data source, it is challenging to automatically identify relevant messages since tweet are short and unstructured, resulting to unsatisfactory classification performance of conventional learning-based approaches. Thus, we propose a simple yet effective algorithm to identify relevant messages based on matching keywords and hashtags, and provide a comparison between matching-based and learning-based approaches. To evaluate the two approaches, we put them into a framework specifically proposed for analyzing disaster-related tweets. Analysis results on eleven datasets with various disaster types show that our technique provides relevant tweets of higher quality and more interpretable results of sentiment analysis tasks when compared to learning approach

    New Active Asteroid (6478) Gault

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    Main-belt asteroid (6478) Gault was observed to show cometary features in early 2019. To investigate the cause, we conducted {\it BVR} observations at Xingming Observatory, China, from 2019 January to April. The two tails were formed around 2018 October 26--November 08, and 2018 December 29--2019 January 08, respectively, and consisted of dust grains of \gtrsim20 μ\mum to 3 mm in radius ejected at a speed of 0.15±0.050.15 \pm 0.05 m s1^{-1} and following a broken power-law size distribution bending at grain radius \sim70 μ\mum (bulk density 1 g cm3^{-3} assumed). The total mass of dust within a 10410^4 km-radius aperture around Gault declined from \sim9×1069 \times 10^6 kg since 2019 January at a rate of 2.28±0.072.28 \pm 0.07 kg s1^{-1}, but temporarily surged around 2019 March 25, because Earth thence crossed the orbital plane of Gault, within which the ejected dust was mainly distributed. No statistically significant colour or short-term lightcurve variation was seen. Nonetheless we argue that Gault is currently subjected to rotational instability. Using the available astrometry, we did not detect any nongravitational acceleration in the orbital motion of Gault.Comment: 6 pages, 4 figures, 2 table

    Coma Anisotropy and the Rotation Pole of Interstellar Comet 2I/Borisov

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    Hubble Space Telescope observations of interstellar comet 2I/Borisov near perihelion show the ejection of large (>~100 um) particles at <~9 m/s speeds, with estimated mass-loss rates of ~35 kg/s. The total mass loss from comet Borisov corresponds to loss of a surface shell on the nucleus only ~0.4 m thick. This shell is thin enough to be susceptible to past chemical processing in the interstellar medium by cosmic rays, meaning that the ejected materials cannot necessarily be considered as pristine. Our high-resolution images reveal persistent asymmetry in the dust coma, best explained by a thermal lag on the rotating nucleus causing peak mass loss to occur in the comet nucleus afternoon. In this interpretation, the nucleus rotates with an obliquity of 30 deg (pole direction RA = 205 deg and Dec. = 52 deg). The subsolar latitude varied from -35 deg (southern solstice) at the time of discovery to 0 deg (equinox) in 2020 January, suggesting the importance of seasonal effects. Subsequent activity likely results from regions freshly activated as the northern hemisphere is illuminated for the first time.Comment: 8 pages, 7 figure

    Optimization of DNA extraction from human urinary samples for mycobiome community profiling.

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    IntroductionRecent data suggest the urinary tract hosts a microbial community of varying composition, even in the absence of infection. Culture-independent methodologies, such as next-generation sequencing of conserved ribosomal DNA sequences, provide an expansive look at these communities, identifying both common commensals and fastidious organisms. A fundamental challenge has been the isolation of DNA representative of the entire resident microbial community, including fungi.Materials and methodsWe evaluated multiple modifications of commonly-used DNA extraction procedures using standardized male and female urine samples, comparing resulting overall, fungal and bacterial DNA yields by quantitative PCR. After identifying protocol modifications that increased DNA yields (lyticase/lysozyme digestion, bead beating, boil/freeze cycles, proteinase K treatment, and carrier DNA use), all modifications were combined for systematic confirmation of optimal protocol conditions. This optimized protocol was tested against commercially available methodologies to compare overall and microbial DNA yields, community representation and diversity by next-generation sequencing (NGS).ResultsOverall and fungal-specific DNA yields from standardized urine samples demonstrated that microbial abundances differed significantly among the eight methods used. Methodologies that included multiple disruption steps, including enzymatic, mechanical, and thermal disruption and proteinase digestion, particularly in combination with small volume processing and pooling steps, provided more comprehensive representation of the range of bacterial and fungal species. Concentration of larger volume urine specimens at low speed centrifugation proved highly effective, increasing resulting DNA levels and providing greater microbial representation and diversity.ConclusionsAlterations in the methodology of urine storage, preparation, and DNA processing improve microbial community profiling using culture-independent sequencing methods. Our optimized protocol for DNA extraction from urine samples provided improved fungal community representation. Use of this technique resulted in equivalent representation of the bacterial populations as well, making this a useful technique for the concurrent evaluation of bacterial and fungal populations by NGS

    Accuracy of magnetic resonance studies in the detection of chondral and labral lesions in femoroacetabular impingement : systematic review and meta-analysis

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    Background: Several types of Magnetic resonance imaging (MRI) are commonly used in imaging of femoroacetabular impingement (FAI), however till now there are no clear protocols and recommendations for each type. The aim of this meta-analysis is to detect the accuracy of conventional magnetic resonance imaging (cMRI), direct magnetic resonance arthrography (dMRA) and indirect magnetic resonance arthrography (iMRA) in the diagnosis of chondral and labral lesions in femoroacetabular impingement (FAI). Methods: A literature search was finalized on the 17th of May 2016 to collect all studies identifying the accuracy of cMRI, dMRA and iMRA in diagnosing chondral and labral lesions associated with FAI using surgical results (arthroscopic or open) as a reference test. Pooled sensitivity and specificity with 95% confidence intervals using a random-effects meta-analysis for MRI, dMRA and iMRA were calculated also area under receiver operating characteristic (ROC) curve (AUC) was retrieved whenever possible where AUC is equivocal to diagnostic accuracy. Results: The search yielded 192 publications which were reviewed according inclusion and exclusion criteria then 21 studies fulfilled the eligibility criteria for the qualitative analysis with a total number of 828 cases, lastly 12 studies were included in the quantitative meta-analysis. Meta-analysis showed that as regard labral lesions the pooled sensitivity, specificity and AUC for cMRI were 0.864, 0.833 and 0.88 and for dMRA were 0.91, 0.58 and 0.92. While in chondral lesions the pooled sensitivity, specificity and AUC for cMRI were 0.76, 0.72 and 0.75 and for dMRA were 0.75, 0.79 and 0.83, while for iMRA were sensitivity of 0.722 and specificity of 0.917. Conclusions: The present meta-analysis showed that the diagnostic test accuracy was superior for dMRA when compared with cMRI for detection of labral and chondral lesions. The diagnostic test accuracy was superior for labral lesions when compared with chondral lesions in both cMRI and dMRA. Promising results are obtained concerning iMRA but further studies still needed to fully assess its diagnostic accuracy

    Ripple Texturing of Suspended Graphene Atomic Membranes

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    Graphene is the nature's thinnest elastic membrane, with exceptional mechanical and electrical properties. We report the direct observation and creation of one-dimensional (1D) and 2D periodic ripples in suspended graphene sheets, using spontaneously and thermally induced longitudinal strains on patterned substrates, with control over their orientations and wavelengths. We also provide the first measurement of graphene's thermal expansion coefficient, which is anomalously large and negative, ~ -7x10^-6 K^-1 at 300K. Our work enables novel strain-based engineering of graphene devices.Comment: 15 pages, 4 figure

    An RxLR effector from phytophthora infestans prevents re-localisation of two plant NAC transcription factors from the endoplasmic reticulum to the nucleus

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    The plant immune system is activated following the perception of exposed, essential and invariant microbial molecules that are recognised as non-self. A major component of plant immunity is the transcriptional induction of genes involved in a wide array of defence responses. In turn, adapted pathogens deliver effector proteins that act either inside or outside plant cells to manipulate host processes, often through their direct action on plant protein targets. To date, few effectors have been shown to directly manipulate transcriptional regulators of plant defence. Moreover, little is known generally about the modes of action of effectors from filamentous (fungal and oomycete) plant pathogens. We describe an effector, called Pi03192, from the late blight pathogen Phytophthora infestans, which interacts with a pair of host transcription factors at the endoplasmic reticulum (ER) inside plant cells. We show that these transcription factors are released from the ER to enter the nucleus, following pathogen perception, and are important in restricting disease. Pi03192 prevents the plant transcription factors from accumulating in the host nucleus, revealing a novel means of enhancing host susceptibility

    Developmentally appropriate guidelines for technology augmented pre-schooler toys

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    Kim To Tse investigated the concerns in creating developmentally appropriate technology augmented pre-schooler toys. He found that parents and child development specialists care for pre-schoolers from different angles. His research outcomes advocate and support the vision of healthy implementation of technology in early childhood while sustaining the toy industry
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