Aufbau und Inbetriebnahme eines Verbrennungsmotorprüfstandes in eine kompatible Motor-Box.

Ziel dieser Diplomarbeit ist die Dokumentation der Konstruktion, des Aufbaus sowie die Inbetriebnahme eines Prüfstandes. Bei dem Prüfobjekt handelt es sich um einen Otto-Verbrennungsmotor, und zwar um den Opel Ecotec 3 Zylinder Motor mit einem Liter Hubraum. Mithilfe dieses Prüfstandes soll die Motorfunktion unter verschiedenen Betriebsbedingungen untersucht werden

Jeavons Syndrome: 12 Cases

Objectives: Jeavons Syndrome (JS), also known as eyelid myoclonia with absences epilepsy, is a type of idiopathic reflex epilepsy that has primary seizure type eyelid myoclonuses and is characterized by blinking due to seizures or generalized paroxysms at electroencephalography (EEG) and photosensitivity. This study aimed to review JS by following up with the patients with this diagnosis

Evaluation of potential cardiovascular risk protein biomarkers in high severity restless legs syndrome

Restless legs syndrome (RLS) is a common sensorimotor disorder that, in case of severe symptoms, can be very distressing and negatively interfere with quality of life. Moreover, increasing evidences associate RLS with higher risk of cerebrovascular and cardiovascular disease (CVD). The purpose of this study was to quantify two proteins, previously identified by proteomics and potentially linked with CVD risk, namely kininogen-1 (KNG1) and alpha-1-antitrypsin (A1AT), in primary RLS patients at high severity grade (HS-RLS) in comparison to healthy control subjects. Proteins were quantified through enzyme-linked immunosorbent assay (ELISA) in plasma samples from 14 HS-RLS patients and 15 control individuals. The two groups were closely matched for age and gender. The expression level of KNG1 resulted significantly higher (p < 0.001), while A1AT was significantly decreased (p < 0.05) in HS-RLS patients compared to controls, confirming the relationship between these proteins and the disease severity. Furthermore, in patients group the association between the protein concentrations and the following parameters was further evaluated: age, disease onset and diagnosis, scores obtained from the RLS rating scales (Epworth Sleepiness Scale, Pittsburgh Sleep Quality Index, Beck Depression Inventory) and smoking habit. All the considered variables resulted independent of protein levels, so the disease can be reasonably considered the main cause of protein changes. As emerged from the literature, high levels of KNG1 and low amounts of A1AT seem to be related with a highest probability to develop CVD. Consequently, these proteins may be reliable candidate biomarkers of CVD risk in patients with RLS at high severity grade