Propuesta de diseño de una red de trabajo colaborativo para los talleres de confección en Bolonia-Usme, Bogotá D.C., siguiendo la filosofía de los negocios inclusivos propuesta aplicada

El objetivo general de este trabajo de grado es Diseñar una propuesta de Red para el trabajo colaborativo entre talleres de confección ubicados en el sector de Bolonia, localidad de Usme, Bogotá, siguiendo el modelo de Negocios Inclusivos con el propósito de mejorar su competitividad en el mercado . En este trabajo de grado se definieron las condiciones de trabajo colaborativo que determinan un diseño de la Red acorde con las necesidades de los talleres, se identificaron los parámetros y características que deben estar involucrados en el diseño de la misma bajo la filosofía de los Negocios Inclusivos. Adicionalmente, se definieron y documentaron los procesos de operación logística y de soporte de la Red, siguiendo la gestión por procesos definida en la norma ISO 9000. Y finalmente, se realizó una evaluación económica para determinar la viabilidad y los beneficios que se obtendrían mediante el desarrollo del proyecto.The main objective of this paper is to design a v/ork collaborative network for a group of shops of Bolinia- Usme Bogotá D.C., followinig the model of inclusive businesses, in order to improve their competitiveness in the market. The paper has the condition, characteristics and parameters that must be involved in the design of the network. Additionally, in the paper are define and documented the processes of the logistics operation and support of the netv/ork, according to the processes management defined in ISO 9000. Finally, the paper has an economic evaluation use to determine the feasibility and the benefits gained through the project.Ingeniero (a) IndustrialPregrad

On equilibrium in non-hydrostatic metamorphic systems

Metamorphic geology has accumulated a huge body of observation on mineral assemblages that reveal strong patterns in occurrence, summarized, for example, in the idea of metamorphic facies. On the realization that such patterns needed a simple explanation, there has been considerable a posteriori success from adopting the idea that equilibrium thermodynamics can be used on mineral assemblages to make sense of the patterns in terms of, for example, the pressure and temperature of formation of mineral assemblages. In doing so, a particularly simple implicit assumption is made, that mineral assemblages operate essentially hydrostatically. Structural geologists have studied the same rocks for different ends, but, remarkably, the phenomena they are interested in depend on non-hydrostatic stress. We look at the effect of such behaviour on mineral equilibria. With adoption of some plausible assumptions about how metamorphism in the crust works, the consequence of minerals being non-hydrostatically stressed is commonly second order in equilibrium calculations

Carbon disulfide. Just toxic or also bioregulatory and/or therapeutic?

The overview presented here has the goal of examining whether carbon disulfide (CS2) may play a role as an endogenously generated bioregulator and/or has therapeutic value. The neuro- and reproductive system toxicity of CS2 has been documented from its long-term use in the viscose rayon industry. CS2 is also used in the production of dithiocarbamates (DTCs), which are potent fungicides and pesticides, thus raising concern that CS2 may be an environmental toxin. However, DTCs also have recognized medicinal use in the treatment of heavy metal poisonings as well as having potency for reducing inflammation. Three known small molecule bioregulators (SMBs) nitric oxide, carbon monoxide, and hydrogen sulfide were initially viewed as environmental toxins. Yet each is now recognized as having intricate, though not fully elucidated, biological functions at concentration regimes far lower than the toxic doses. The literature also implies that the mammalian chemical biology of CS2 has broader implications from inflammatory states to the gut microbiome. On these bases, we suggest that the very nature of CS2 poisoning may be related to interrupting or overwhelming relevant regulatory or signaling process(es), much like other SMBs

Promoción de conducta prosocial y optimismo en adolescentes

PsicólogoPregrad

A Designed Receptor for pH-Switchable Ion Binding in Water

Molecules with conditional (switchable) properties are of considerable fundamental interest and are potentially useful for a broad range of applications, including chemical sensing. We have prepared a novel receptor, derived from the peracylation of cyclohexane 1,3,5-trimethanol with tyrosine, that suggests that the phenol−amine hydrogen bond may be an effective structural tool in the preparation of molecules with pH-switchable conformations. This conclusion is based on several key observations. First, the proton longitudinal relaxation rates for this molecule change in a pH-dependent fashion, while those for closely related structures do not. Second, NOESY spectra for the receptor change markedly depending on pH, with the spectrum acquired at pH 9.5 displaying NOEs consistent with the calculated “closed” conformation. Third, this molecule serves as a receptor for anions and cations in aqueous solution at high pH, but not at low pH, as demonstrated by UV−vis titrations and isothermal titration calorimetry (ITC)

Flow Analysis in a Steam Turbine Control Valve With Through-Flow Valve Chamber

Abstract A nuclear power plant also includes a secondary cycle, which main component is a steam turbine. The steam turbine processes the thermal and pressure energy of steam and converts it into mechanical energy. Reliable and safe operation of the steam turbine, thus of the entire block, is ensured by valves. The flow in a pair of control valves, where the steam flows through the valve chamber past the first valve to the second valve, is investigated in this paper. The experimentally determined flow characteristics of both valves were evaluated and results were generalized. The experiments were carried out in the Aerodynamic laboratory of the Institute of Thermomechanics of the Czech Academy of Sciences in Novy Knin where a wind tunnel for high speeds could be used. Data of the distribution of pressures in selected places were evaluated. The energy loss in the valves was compared with the loss in a separate diffuser with varying degrees of expansion. The influence of a valve strainer, which is a part situated upstream of the control valve cone, was also investigated. It was found out in which case and where there is a significant disturbance of the velocity flow field. The first valve in the chamber is more sensitive to pressure losses in contrast to the second valve which is comparable to an ideal design of the diffuser, which indicates that this part of the valve assembly is optimal. Regarding the strainers, it was found out that the strainer helps to balance the velocity ratios at the inlet to the valve which has a positive effect on reducing the total energy pressure loss. As a result, the loss in the first valve can be significantly reduced which helps to increase the efficiency of the whole turbine.</jats:p