Echocardiographic recognition of a criss-cross heart with double outlet right ventricle

Crisscross heart (CCH) is a rare cardiac malformation characterized by crossing of the inflow streams of the two ventricles due to an apparent twisting of the heart about its long axis. The developmental mechanisms and causes of CCH are remaining unknown. Neonates mainly presents with cyanosis and a systolic murmur. This article presents a case of CCH with concordant atrioventriculo connections with double outlet right ventricle (DORV), which was diagnosed by echocardiography.peer-reviewe

Arthrogryposis: A Rare Manifestation in Infant of Diabetic Mother

Arthrogryposis multiplex congenita is characterized by non-progressive, multiple joint contractures present at birth. The major cause of arthrogryposis is fetal akinesia due to fetal abnormalities like neurogenic, muscle, connective tissue abnormalities or maternal disorders Here we report a rare case of arthrogryposis in infant of diabetic mother with multiple congenital anomalies

Double orifice mitral valve associated with Ventricular Septal Defect in an infant : case report

Double orifice mitral valve (DOMV) is an uncommon anomaly characterized by a mitral valve with a single fibrous annulus with two orifices opening into the left ventricle. Here we present a rare case of DOMV with ventricular septal defect (VSD) which was detected by 2-D echocardiography.peer-reviewe

Optimal Traffic Splitting Policy in LTE-based Heterogeneous Network

Dual Connectivity (DC) is a technique proposed to address the problem of increased handovers in heterogeneous networks. In DC, a foreground User Equipment (UE) with multiple transceivers has a possibility to connect to a Macro eNodeB (MeNB) and a Small cell eNodeB (SeNB) simultaneously. In downlink split bearer architecture of DC, a data radio bearer at MeNB gets divided into two; one part is forwarded to the SeNB through a non-ideal backhaul link to the UE, and the other part is forwarded by the MeNB. This may lead to an increase in the total delay at the UE since different packets corresponding to a single transmission may incur varying amounts of delays in the two different paths. Since the resources in the MeNB are shared by background legacy users and foreground users, DC may increase the blocking probability of background users. Moreover, single connectivity to the small cell may increase the blocking probability of foreground users. Therefore, we target to minimize the average delay of the system subject to a constraint on the blocking probability of background and foreground users. The optimal policy is computed and observed to contain a threshold structure. The variation of average system delay is studied for changes in different system parameters.Comment: Conferenc

Nanostructured Cubosomes in a Thermoresponsive Depot System: An Alternative Approach for the Controlled Delivery of Docetaxel

The aim of the present study was to develop and evaluate a thermoresponsive depot system comprising of docetaxel-loaded cubosomes. The cubosomes were dispersed within a thermoreversible gelling system for controlled drug delivery. The cubosome dispersion was prepared by dilution method, followed by homogenization using glyceryl monooleate, ethanol and Pluronic® F127 in distilled water. The cubosome dispersion was then incorporated into a gelling system prepared with Pluronic®F127 and Pluronic® F68 in various ratios to formulate a thermoresponsive depot system. The thermoresponsive depot formulations undergo a thermoreversible gelation process i.e., they exists as free flowing liquids at room temperature, and transforms into gels at higher temperatures e.g., body temperature, to form a stable depot in aqueous environment. The mean particle size of the cubosomes in the dispersion prepared with Pluronic® F127, with and without the drug was found to be 170 and 280 nm, respectively. The prepared thermoresponsive depot system was evaluated by assessing various parameters like time for gelation, injectability, gel erosion, and in-vitro drug release. The drug-release studies of the cubosome dispersion before incorporation into the gelling system revealed that a majority (∼97%) of the drug was released within 12 h. This formulation also showed a short lag time (∼3 min). However, when incorpo- rated into a thermoresponsive depot system, the formulation exhibited an initial burst release of∼21%, and released only∼ 39% drug over a period of 12 h, thus indicating its potential as a controlled drug delivery system

Simulation Analysis of New 802.11KT MAC Protocol And IEEE 802.11 MAC Protocol for Grid Topology in MANET Using NS-2

This paper compare the performance analysis of newly designed 802.11KT MAC protocol for a mobile ad-hoc network (MANET) communication system which aims to provide low cost, small end to end delay and more throughputs with the existing IEEE 802.11 MAC protocol. Simulation is the main method for evaluating the performance of protocol. It is subjected to comparison of performance of existing IEEE802.11 Mac protocol and new 802.11KT Mac protocol for random topology in MANET. The Adhoc On Demand Distance Vector (AODV) is used as routing protocol with NS-2 simulator. Simulation results indicated that newly designed 802.11KT MAC protocol has better performance than existing IEEE 802.11 MAC protocol