Community perceptions of free-roaming dogs and management practices in villages at the periphery of a protected area in Bhutan

In Bhutan, free-roamingdogs pose health hazards to human, livestock, andwildlife. Understanding the perceptions and practices of local communitiesregarding free-roaming dogs is important to mitigate negative impacts. A community-based study was conducted inthe buffer zone of Strict Nature Reserve, western Bhutan. The study was conducted in February-October 2018 using a household questionnairesurvey, 'free-listing'of dog diseases, group discussions and key-informantinterviews.A total of 140 householdsfromKatsho and Esuegeogs(sub-districts) were interviewed. People classify dogs under three categories: 'Gokhi'/petdog, 'Changkhi'/stray dog, and 'Shakhi'/feraldog. A higher proportion of rural people owned pet dogs, which were considered important to guard crops and livestock from wildlifeandprotect households'properties. Owning a dog also contributed significantly to the non-material well-beingof the respondents, especially in the rural villages. In contrast to the perceived positive impacts of the pet dogs,81%of the respondents considered stray and feral dogs a problem in thecommunity.The threats were attacks/bites by free-roaming dogs to humans, livestock and also wildlife. Rabies was the most frequently (69.7%) known dog diseases with the highest rank (1.46) in the list, followed by scabies (49.5%, rank1.52). The majority (56%) of the respondents indicated that stray and feral dogs originate from abandoned pet dogs. This study calls for a multi-sectorial/One Health approach to mitigate the threats posed by free-roaming dogs and more detailed ecological and epidemiological studies are required to control their impacts

Health Perception and Health Behaviors of Elder Tibetans Living in India and Switzerland

Tibetan elders have lived in exile since the failed uprising against Chinese rule in 1959. Using mixed methods approach, this study explored the perceived health and health behaviors of 30 older Tibetans living in India and Switzerland using Bronfenbrenner's Ecological Systems Model. Results indicate that elder Tibetans living in Switzerland enjoyed better health and well-being than those living in India. Because of the availability of old age benefits, pensions, and health insurance, participants in Switzerland had greater financial independence, and fewer problems with healthcare access and affordability than those in India. In addition to financial reimbursement, the contribution and importance of personal, familial, community, and religious factors to participant's health behaviors are examined. The study is a case example depicting the impact of different factors from micro to macro on the health and well-being of a refugee group. Its implications such as the implementation of old age benefits for older persons living in developing countries are discusse

Which GABA Receptors Are Expressed in the Zebrafish Lateral Line?

The presence of the neurotransmitter GABA in the mammalian inner ear is well established, yet its role in regulating inner ear cell function is less clear. We seek to understand the role of the GABA in the inner ear using the model organism zebrafish. Zebrafish possess a sense that humans do not: they can detect water movement with their lateral line system. Zebrafish sense water movement with cells that project out from the body of the fish into the environment. These so-called hair cells are remarkably similar to the sensory cells of the cochlea and semi-circular canals. Because they are on the outside of the zebrafish, and not behind a bony skull, lateral line hair cells are easily accessible to study. Therefore, we are determining if we can use the lateral line system to understand more about GABA in the inner ear. We have used RNA extraction and RT-PCR to detect the expression of 27 GABA-related genes in zebrafish. We have also identified a novel alternative exon in one isoform. Overall, our results suggest that the genes expressed in the lateral line are orthologs of genes expressed in the mammalian inner ear, and thus zebrafish appear to be an appropriate model organism with which to further study GABA function in the inner ear

Smoking is injurious to your child, even after pregnancy : Folgen des maternalen Zigarettenkonsums für das gestillte Kind

Darstellung des Themas: Viele Raucherinnen verzichten während der Schwangerschaft, der Gesundheit des Kindes zuliebe, auf das Rauchen. Die Rückfallquote nach der Entbindung ist sehr hoch. Jedoch scheint das Kind auch während der Stillperiode durch das mütterliche Rauchen gefährdet zu sein. Ziel: Mit Hilfe dieser Bachelorarbeit sollen die in der Literatur beschriebenen Auswirkungen des maternalen Rauchens auf das gestillte Kind aufgezeigt werden. Anhand der Ergebnisse wird eine Beratungsgrundlage für Hebammen erstellt. Methode: Mittels Literaturrecherche wird in medizinischen Fachdatenbanken nach evidenzbasierter Literatur gesucht. Unter Berücksichtigung von festgelegten Ein- und Ausschlusskriterien werden vier relevante Studien ausgewählt und bewertet. Relevante Ergebnisse: Nebst der Wachstumseinschränkung während des Stillens und vermehrter Gewichtszunahme im späteren Alter werden durch das mütterliche Rauchen auch Kreislauf und Verdauung dieser Kinder beeinträchtigt. Diese Kinder sind dazu vermehrt unruhig und verbringen weniger Zeit im Aktivschlaf. Ebenfalls kann durch das starke Rauchen eine erhöhte Leukämierate im Kindesalter beobachtet werden. Schlussfolgerung: Es ist Aufgabe der Hebammen diese Frauen schon früh auf dieses Thema anzusprechen und über die möglichen Folgen des Rauchens während der Stillperiode zu informieren. Eine einheitliche Beratung wäre dabei sinnvol

Optogenetic activation of accessory olfactory bulb input to the forebrain differentially modulates investigation of opposite versus same-sex urinary chemosignals and stimulates mating in male mice

Surgical or genetic disruption of vomeronasal organ (VNO)-accessory olfactory bulb (AOB) function previously eliminated the ability of male mice to processes pheromones that elicit territorial behavior and aggression. By contrast, neither disruption significantly affected mating behaviors, although VNO lesions reduced males' investigation of nonvolatile female pheromones. We explored the contribution of VNO-AOB pheromonal processing to male courtship using optogenetic activation of AOB projections to the forebrain. Protocadherin-Cre male transgenic mice received bilateral AOB infections with channelrhodopsin2 (ChR2) viral vectors, and an optical fiber was implanted above the AOB. In olfactory choice tests, males preferred estrous female urine (EFU) over water; however, this preference was eliminated when diluted (5%) EFU was substituted for 100% EFU. Optogenetic AOB activation concurrent with nasal contact significantly augmented males' investigation compared to 5% EFU alone. Conversely, concurrent optogenetic AOB activation significantly reduced males' nasal investigation of diluted urine from gonadally intact males (5% IMU) compared to 5% IMU alone. These divergent effects of AOB optogenetic activation were lost when males were prevented from making direct nasal contact. Optogenetic AOB stimulation also failed to augment males' nasal investigation of deionized water or of food odors. Finally, during mating tests, optogenetic AOB stimulation delivered for 30 s when the male was in physical contact with an estrous female significantly facilitated the occurrence of penile intromission. Our results suggest that VNO-AOB signaling differentially modifies males' motivation to seek out female vs male urinary pheromones while augmenting males' sexual arousal leading to intromission and improved reproductive performance