Access Granted: A Demographic Analysis of How The Pandemic Has Disrupted the Monocentric City

Abstract This study shows the disruption that the Covid pandemic has had on the national relationship between changes in quarterly House Price Index (HPI) values and distance from Metropolitan statistical areas (MSAs). This disruption is statistically modeled through linear regressions where quarterly changes in HPI values are set equal to distance as well as factors such as change in population, housing units, and home ownership. Special recognition is also given to the distance relationship during years affected by Covid. This disruption is then analyzed in relation to demographic factors such as age and race. The study showed that the disruption of younger cities, cities whose median age was in the bottom 25th percentile, was twice that of the population which could suggest that younger people relocated outside of MSAs at a greater rate than older people. The study also showed that non-minority cities, cities whose minority makeup was in the bottom 25th percentile, exhibited stronger monocentric characteristics prior to Covid than the entire population which could suggest that further research could be conducted on pre-existing public policies and their effect on the disruption on the distribution of home values

Access Granted: A Demographic Analysis of How the Pandemic Has Disrupted the Monocentric City Model

The Objective of my research is to quantify the effect that the Covid Pandemic has had on the distribution of home values in regard to the monocentric city model as well as identify and explain any demographic variables that have hindered or aided this disruption.https://egrove.olemiss.edu/hon_posters/1000/thumbnail.jp

Capturing Style in Author and Document Representation

A wide range of Deep Natural Language Processing (NLP) models integrates continuous and low dimensional representations of words and documents. Surprisingly, very few models study representation learning for authors. These representations can be used for many NLP tasks, such as author identification and classification, or in recommendation systems. A strong limitation of existing works is that they do not explicitly capture writing style, making them hardly applicable to literary data. We therefore propose a new architecture based on Variational Information Bottleneck (VIB) that learns embeddings for both authors and documents with a stylistic constraint. Our model fine-tunes a pre-trained document encoder. We stimulate the detection of writing style by adding predefined stylistic features making the representation axis interpretable with respect to writing style indicators. We evaluate our method on three datasets: a literary corpus extracted from the Gutenberg Project, the Blog Authorship Corpus and IMDb62, for which we show that it matches or outperforms strong/recent baselines in authorship attribution while capturing much more accurately the authors stylistic aspects

RAFT dispersion polymerization : a method to tune the morphology of thymine-containing self-assemblies

YesThe synthesis and self-assembly of thymine-containing polymers were performed using RAFT dispersion polymerization. A combination of microscopy and scattering techniques was used to analyze the resultant complex morphologies. The primary observation from this study is that the obtained aggregates induced during the polymerization were well-defined despite the constituent copolymers possessing broad dispersities. Moreover, a variety of parameters, including the choice of polymerization solvent, the degree of polymerization of both blocks and the presence of an adenine-containing mediator, were observed to affect the resultant size and shape of the assembly.University of Warwick, National Science Foundation (U.S.) (NSF), Engineering and Physical Sciences Research Council (EPSRC

The N-terminal domains of TRF1 and TRF2 regulate their ability to condense telomeric DNA

TRF1 and TRF2 are key proteins in human telomeres, which, despite their similarities, have different behaviors upon DNA binding. Previous work has shown that unlike TRF1, TRF2 condenses telomeric, thus creating consequential negative torsion on the adjacent DNA, a property that is thought to lead to the stimulation of single-strand invasion and was proposed to favor telomeric DNA looping. In this report, we show that these activities, originating from the central TRFH domain of TRF2, are also displayed by the TRFH domain of TRF1 but are repressed in the full-length protein by the presence of an acidic domain at the N-terminus. Strikingly, a similar repression is observed on TRF2 through the binding of a TERRA-like RNA molecule to the N-terminus of TRF2. Phylogenetic and biochemical studies suggest that the N-terminal domains of TRF proteins originate from a gradual extension of the coding sequences of a duplicated ancestral gene with a consequential progressive alteration of the biochemical properties of these proteins. Overall, these data suggest that the N-termini of TRF1 and TRF2 have evolved to finely regulate their ability to condense DNA

DNA Physical Properties and Nucleosome Positions Are Major Determinants of HIV-1 Integrase Selectivity

Retroviral integrases (INs) catalyse the integration of the reverse transcribed viral DNA into the host cell genome. This process is selective, and chromatin has been proposed to be a major factor regulating this step in the viral life cycle. However, the precise underlying mechanisms are still under investigation. We have developed a new in vitro integration assay using physiologically-relevant, reconstituted genomic acceptor chromatin and high-throughput determination of nucleosome positions and integration sites, in parallel. A quantitative analysis of the resulting data reveals a chromatin-dependent redistribution of the integration sites and establishes a link between integration sites and nucleosome positions. The co-activator LEDGF/p75 enhanced integration but did not modify the integration sites under these conditions. We also conducted an in cellulo genome-wide comparative study of nucleosome positions and human immunodeficiency virus type-1 (HIV-1) integration sites identified experimentally in vivo. These studies confirm a preferential integration in nucleosome-covered regions. Using a DNA mechanical energy model, we show that the physical properties of DNA probed by IN binding are important in determining IN selectivity. These novel in vitro and in vivo approaches confirm that IN has a preference for integration into a nucleosome, and suggest the existence of two levels of IN selectivity. The first depends on the physical properties of the target DNA and notably, the energy required to fit DNA into the IN catalytic pocket. The second depends on the DNA deformation associated with DNA wrapping around a nucleosome. Taken together, these results indicate that HIV-1 IN is a shape-readout DNA binding protein

Bi-fractional transforms in phase space

The displacement operator is related to the displaced parity operator through a two dimensional Fourier transform. Both operators are important operators in phase space and the trace of both with respect to the density operator gives the Wigner functions (displaced parity operator) and Weyl functions (displacement operator). The generalisation of the parity-displacement operator relationship considered here is called the bi-fractional displacement operator, O(α, β; θα, θβ). Additionally, the bi-fractional displacement operators lead to the novel concept of bi-fractional coherent states. The generalisation from Fourier transform to fractional Fourier transform can be applied to other phase space functions. The case of the Wigner-Weyl function is considered and a generalisation is given, which is called the bi-fractional Wigner functions, H(α, β; θα, θβ). Furthermore, the Q−function and P−function are also generalised to give the bi-fractional Q−functions and bi-fractional P−functions respectively. The generalisation is likewise applied to the Moyal star product and Berezin formalism for products of non-commutating operators. These are called the bi-fractional Moyal star product and bi-fractional Berezin formalism. Finally, analysis, applications and implications of these bi-fractional transforms to the Heisenberg uncertainty principle, photon statistics and future applications are discussed

Opération développement artisanat rural : rapport annuel 1977

Déroulement et résultats des principaux travaux du responsable de l'opération développement de l'artisanat rural. Il devait procéder à la connaissance du milieu, déterminer une politique et un schéma d'action avec l'O.N.D.R., définir les zones d'action et l'équipement nécessaire, recruter et former des instructeurs, organiser l'approvisionnement en outillage et main d'oeuvre, lancer la formation. En annexe : parc du matériel de culture attelée et effectif du cheptel bovi

Rapport annuel : opération développement artisanat rural, 1978

L'opération développement artisanat rural fonctionne au Tchad depuis janvier 1977. Ses activités ont porté sur les préparations : - connaissance du milieu; - déterminer une politique et un schéma d'action; - définir les zones d'ation; - définir l'équipement nécessaire; - recruter et former des instructeurs; - organiser l'approvisionnement en outillage et matière d'oeuvre; - lancer la formation. Le présent rapport fait le point sur le programme d'activités et jete les bases de la future opératio

Opération développement artisanat rural : rapport janvier-mars 1979

Analyse critique des stages de formation de forgeron : la construction de l'atelier pose problème (perte de temps pour les stagiaires, pas de compensation pour le forgeron qui reçoit) mais a de nombreux avantages , avis des stagiaires sur le contenu de l'enseignement , leur niveau de base et la qualité du travail effectué. Prise en charge par le représentant de l'ONDR zone sud des reliquas et de la suite des opérations (équipement des stagiaires, recouvrement des crédits...) du fait des évènements politique