Research into self-help groups and speed school graduates' experiences of schooling

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Assessment of efficacy and quality of two albendazole brands commonly used against soil-transmitted helminth infections in school children in Jimma Town, Ethiopia

Background : There is a worldwide upscale in mass drug administration (MDA) programs to control the morbidity caused by soil-transmitted helminths (STHs): Ascaris lumbricoides, Trichuris trichiura and hookworm. Although anthelminthic drugs which are used for MDA are supplied by two pharmaceutical companies through donation, there is a wide range of brands available on local markets for which the efficacy against STHs and quality remain poorly explored. In the present study, we evaluated the drug efficacy and quality of two albendazole brands (Bendex and Ovis) available on the local market in Ethiopia. Methodology/Principal Findings : A randomized clinical trial was conducted according to the World Health Organization (WHO) guidelines to assess drug efficacy, by means of egg reduction rate (ERR), of Bendex and Ovis against STH infections in school children in Jimma, Ethiopia. In addition, the chemical and physicochemical quality of the drugs was assessed according to the United States and European Pharmacopoeia, encompassing mass uniformity of the tablets, amount of active compound and dissolution profile. Both drugs were highly efficacious against A. lumbricoides (>97%), but showed poor efficacy against T. trichiura (similar to 20%). For hookworms, Ovis was significantly (p < 0.05) more efficacious compared to Bendex (98.1% vs. 88.7%). Assessment of the physicochemical quality of the drugs revealed a significant difference in dissolution profile, with Bendex having a slower dissolution than Ovis. Conclusion/Significance : The study revealed that differences in efficacy between the two brands of albendazole (ABZ) tablets against hookworm are linked to the differences in the in-vitro drug release profile. Differences in uptake and metabolism of this benzimidazole drug among different helminth species may explain that this efficacy difference was only observed in hookworms and not in the two other species. The results of the present study underscore the importance of assessing the chemical and physicochemical quality of drugs before conducting efficacy assessment in any clinical trials to ensure appropriate therapeutic efficacy and to exclude poor drug quality as a factor of reduced drug efficacy other than anthelminthic resistance. Overall, this paper demonstrates that "all medicines are not created equal"

Evaluation of potato (Solanum tuberosum L.) genotypes for resistance to late blight at Sinana Southeastern Ethiopia

Late blight caused by Phytophthora infestans (Mont.) de Bary, is one of the most significant constraints to potato production in Bale high lands and other regions of Ethiopia. Hence, this requires to develop high yielding and late blight resistant varieties. Therefore, this study was conducted to determine host resistance of potato against Phytophthora infestans in order to develop late blight resistant/tolerant genotypes. The experiment was laid out in randomized complete block design with three replications at Sinana Agricultural Research Center during 2014 main cropping season. The genotypes showed highly significant (P&lt;0.01) differences for all the characters studied. Genotypes exhibited wide ranges of mean values for all characters. The highest total tuber yield (46.1 t ha-1) was obtained from the advanced clone, CIP-392640.524 followed by Belete (41 t ha-1). Late blight appeared early on farmer's cultivar Kellacho (48 days after planting) and late on advanced clones CIP- 399062.102(74 days after planting). Percent severity index (PSI) and area under disease progress curve (AUDPC) ranged from 33.91 to 91.67% and 105 to 2370, respectively. Eleven newly introduced clones and the released variety "Belete" recorded PSI 33 to 39.7% and AUDPC 105 to 264.1. Hence, these genotypes can be categorized as moderately resistant. The study revealed the presence of considerable variability in tested genotypes for economically important traits and the higher chance of selecting genotypes with high yield and moderately resistant to late blight. However, it appears that further evaluation of genotypes across seasons and locations to identify genotypes that could be released as varieties seem to be quite pertinent.Int. J. Agril. Res. Innov. &amp; Tech. 6 (1): 21-25, June, 201

Evaluation of crop residue retention, compost and inorganic fertilizer application on barley productivity and soil chemical properties in the central Ethiopian Highlands

Soil fertility depletion is a serious problem in the highlands of Ethiopia. A field experiment was conducted for two consecutive cropping seasons (2009-2010) on farmers’ fields in Degem Wereda, North Shewa, Oromiya Regional State. The objective of this study was to evaluate the effects of crop residue, compost, inorganic fertilizer and cropping system as a component of an integrated soil fertility and plant nutrient management system on barley productivity and soil chemical properties. The treatments included eight selected combinations of organic and inorganic nutrient sources, including retention of crop residues. The design was randomized complete block with three replications. Results showed that barley yield and some yield components significantly responded to the application of different soil fertility management practices. The highest barley grain yield (2575 kg/ha) and total biomass (5185 kg/ha) were obtained from the applications of the recommended nitrogen and phosphorus (NP) fertilizer followed by 2353 and 5148 kg/ha for grain yield and total biomass, respectively, due to the applications of half doses of the recommended NP fertilizer and 3 t/ha EM-compost. The grain yield of barley consistently increased as the total biomass increased. Although the highest yields were achieved from the application of the recommended NP fertilizer rate, the other integrated soil fertility management treatments also resulted in significant yield advantages compared to the control. Yields from the applications of three treatments 1/ half the recommended rate of NP fertilizer and 3 t/ha conventional compost; 2/ retention of 30% of crop residue plus half the recommended rate of NP fertilizer and faba bean mixed intercropping; and 3/ half doses of NP fertilizer plus 3 t/ha EM-compost were almost identical. Barley grain yield showed significantly positive correlations with the total biomass (r = 0.94), spike length (r = 0.43) and number of productive tillers (r = 0.42), respectively. Partitioning of treatments into single degrees of freedom orthogonal contrasts revealed that barley grain yield, total biomass, spike length and productive tillers significantly differed due to the different soil fertility management treatments. From the results of this study, it can be concluded that application of half the recommended rate of NP fertilizer with 50% of the recommended dose of compost (3 t/ha) can be an alternative best integrated soil fertility management measure instead of only inorganic fertilizers for sustainability. The results of this experiment can be reproducible in other similar agro-ecologies and farming systems of the country.Keywords: Barley productivity, chemical soil properties, compost, crop residue, inorganic fertilizer, sustainabilit

Seroepidemiological study of ovine toxoplasmosis in East and West Shewa Zones of Oromia Regional State, Central Ethiopia

Background: Toxoplasmosis is a globally distributed zoonosis. Consumption of raw or undercooked meat, which is among the main risk factors for acquiring human infection, is a popular tradition in Ethiopia. However, studies on toxoplasmosis in food animals used for human consumption in Ethiopia are very scarce. Thus, the objectives of the present study were to estimate the seroprevalence and the risk factors of T. gondii infection in sheep in Ambo, Ada'a-Liben and Fentale districts of Central Ethiopia. Sera from 1130 sheep were analyzed for Toxoplasma gondii specific IgG antibodies using an indirect enzyme linked immunosorbent assay (ELISA) with the P30 antigen. A questionnaire was administered to assess potential risk factors for T. gondii seropositivity. Association of seroprevalence with potential risk factors related to altitude, host and farm characteristics were analyzed by univariable and multivariable logistic regression. Results: Overall flock and animal level seroprevalences were 70.48% (160/227; 95% CI: 64.51, 76.46) and 31.59% (357/1130; 95% CI: 28.88, 34.31), respectively. The multivariable logistic regression model indicated that the probability of acquiring T. gondii was higher in sheep from highland (2300 - 3200 meters above sea level) [Odds ratio (OR) = 4.11, 95% confidence interval (CI): 2.65, 6.36; P < 0.001] and midland (OR = 4.54, 95% CI: 2.76, 7.49; P < 0.001) than from lowland (< 1500 meters above sea level), in females than in males (OR = 1.60, 95% CI: 1.04, 2.43, P = 0.033), in adult than in young animals (OR = 2.93, 95% CI: 1.97, 4.35, P < 0.001), in small than in large flocks (OR = 3.34, 95% CI: 1.26, 8.86, P = 0.016), and in sheep that were given tap water (OR = 4.07, 95% CI: 1.07, 15.42, P = 0.039) and river water (OR = 4.18, 95% CI: 1.54, 11.35, P = 0.005) than in those that drunk water from mixed sources (i.e., river, well, lake and pond). Conclusions: The high flock and animal level seroprevalence of toxoplasmosis in sheep is a good marker of the potential risk for human infections. Altitude, sex, age, flock size and source of water were identified as important risk factors to acquire the infection. Public education and awareness training are imperative in order to alleviate the danger posed to consumers. Further detailed studies to assess the impact of infections are warranted

Fizička i kemijska svojstva gorskog bambusa (Yushania alpina) uzgojenoga u Etiopiji

Bamboo is the fastest growing plant currently known on earth, a property that enables it to be the best alternative as a future source of wood fi ber. This study investigated the effect of site and culm height on the physical and chemical properties of Yushania alpina culms grown in Ethiopia. Matured Yushania alpina 3 to 5-year-old samples were harvested from Hagere-Selam and Rebu-Gebeya sites. The culms were subdivided into three equal lengths (bottom, middle, and top), and the variations in physical and chemical properties between the two sites and the culm heights of Yushania alpina were investigated. The results showed that the average values of MC, basic density, tangential and longitudinal shrinkage of Yushania alpina culms for Hagere-Selam and Rebu-Gebeya sites were (91.78 and 80.32 %), (0.65 and 0.63 g/cm3), (6.63 and 5.84 %) and (0.63 and 0.56 %), respectively. The average values of cellulose, lignin, extractive and ash contents in the culms for Hagere-Selam and Rebu-Gebeya sites were (52.84 and 50.71 %), (26.55, and 26.04 %), (8.41 and 8.02 %) and (1.95 and 2.17 %), respectively. The results revealed that the site affected the MC, basic density, cellulose, lignin, extractive, and ash contents of Yushania alpina culms but not the tangential and longitudinal shrinkage. The culm height of Yushania alpina affected MC, basic density, tangential shrinkage, longitudinal shrinkage, cellulose, lignin, extractive, and ash contents. In the case of both sites, the highest percentages of MC, tangential and longitudinal shrinkage, and ash content were observed at the base and lowest at the top of the culms. On the contrary, both sites observed thehighest magnitude of basic density, cellulose and extractive at the top and lowest at the base of the culms. The variations in physical and chemical properties at different sites and culm heights infl uence the utilization of Yushania alpina culms for industries and end products.Bambus je trenutačno najbrže rastuća biljka u svijetu, što je čini najboljom alternativom za budući izvor drvnih vlakana. Ovom je studijom istraživan utjecaj staništa i visine bambusa Yushania alpina, uzgojenoga u Etiopiji, na fizička i kemijska svojstva njegove stabljike. Uzorci Yushania alpina stari tri do pet godina skupljeni su sa staništa Hagere-Selam i Rebu-Gebeya. Stabljike su podijeljene na tri jednake duljine (baza, sredina i vrh) na kojima su istraživane varijacije fizičkih i kemijskih svojstava stabljike s obzirom na dva staništa i visinu bambusa. Rezultati su pokazali da su prosječne vrijednosti sadržaja vode, gustoće te tangentnoga i uzdužnog utezanja stabljike Yushania alpina sa staništa Hagere-Selam i Rebu-Gebeya bile 91,78 i 80,32 %; 0,65 i 0,63 g/cm3; 6,63 i 5,84 % te 0,63 i 0,56 %, a prosječne vrijednosti sadržaja celuloze, lignina, ekstraktiva i pepela sa staništa Hagere-Selam i Rebu-Gebeya bile su 52,84 i 50,71 %; 26,55 i 26,04 %; 8,41 i 8,02 % te 1,95 i 2,17 %. Rezultati su pokazali da je stanište utjecalo na sadržaj vode, gustoću te sadržaj celuloze, lignina, ekstraktiva i pepela u stabljikama Yushania alpina, ali ne i na tangentno i uzdužno utezanje. Visina stabljike Yushania alpina utjecala je na sadržaj vode, gustoću, tangentno i uzdužno utezanje te na sadržaj celuloze, lignina, ekstraktiva i pepela. Za oba staništa utvrđen je najveći sadržaj vode, tangentno i uzdužno utezanje te sadržaj pepela u bazi stabljike, a najmanji u vrhu stabljike. Nadalje, u vrhu stabljike s oba staništa primijećena je najveća gustoća, sadržaj celuloze i ekstraktiva, a najmanje su vrijednosti izmjerene u bazi stabljike. Varijacije fizičkih i mehaničkih svojstava s obzirom na stanište i visinu stabljike utječu na upotrebu stabljike Yushania alpina u industriji i za završne proizvode

Upscale of sheep and goat community based breeding: Mid term report

Presentation in: Midterm Review and Implementation Support Mission. Addis Ababa, Ethiopia, February 7-18, 2022

Impact of Membership to Certified Coffee Marketing Cooperatives on the Income of Smallholder Farmers in Jimma Zone of Oromia Region, Ethiopia

Purpose: Coffee is one of the most important agricultural commodities with a significant contribution to the growth and well-functioning of Ethiopia\u27s economy, and to the livelihoods of millions of smallholder farmers and laborers. Despite its importance, smallholder coffee production and marketing performance have been unsatisfactory due to various reasons. The introduction of voluntary coffee certification schemes such as Fairtrade (FT) and Organic (Org) certification schemes through cooperatives are viewed as mechanisms to overcome the constraints smallholder farmers face in accessing high value coffee markets and earn better income. However, the impacts of these schemes on the livelihoods of smallholder farmers were not analyzed yet. The main purpose of this study was to estimate the impact of joining (FT, Org or dual FT-Org) certified coffee cooperatives on gross annual incomes earned by member farmers. Methodology: The study employed cross-sectional data collected from randomly selected sample smallholder coffee farmers through a semi-structured questionnaire. Descriptive and simple inferential statistical tests (e.g., frequency, percentage, mean, t-and chi2-tests), and PSM methods were employed to analyze the data. Findings: Results of the descriptive statistics depict that 234 (62.07%) of the total 377 samples farmers were members of certified coffee marketing cooperatives. Among the cooperative members, 83 (35.47%), 84 (35.90%) and 67 (28.63%) were members of FT, Org and dual FT-Org certified coffee marketing cooperatives, respectively. The results of the binary probit model however show that the decisions to join certified coffee marketing cooperatives was significantly influenced by sex, marital status, total livestock holding size, total coffee land size (ha), log total quantity of coffee produced (kg), credit access, and walking distances to development agent\u27s office, coffee marketing center and all-weather road in minutes, respectively. The PSM analysis results show that membership to certified coffee marketing cooperatives has a positive and significant impact on average annual gross income (ETB) earned. The average gross annual income earned by coop member farmers was ETB 14639.15, which is by 36.51% higher than their counterpart non-coop member farmers. The difference is statistically significant at 1% probability level. Unique Contribution to Theory, Practice and Policy: The study recommended that Cooperatives should be encouraged to establish credit and saving units in their internal structure and/or work in collaboration with other saving and credit providing institutions (such as Cooperative Bank&nbsp; of Oromia) to be able to provide demand-driven credit services to member farmers

Prevalence and factors affecting use of long acting and permanent contraceptive methods in Jinka town, Southern Ethiopia: a cross sectional study

Introduction: In Ethiopia, knowledge of contraceptive methods is high though there is low contraceptive prevalence rate. This study was aimed to assess prevalence and associated factors of long acting and permanent contraceptive methods in Jinka town, southern Ethiopia. Methods: Community based cross sectional survey was conducted to assess the prevalence and factors affecting long acting and permanent methods of contraceptives utilization from March to April 2008. Eight hundred child bearing age women were participated in the quantitative study and 32 purposively selected focus group discussants were participated in the qualitative study. Face to face interview was used for data collection. Data were analyzed by SPSS version 13.0 statistical software. Descriptive statistics and logistic regression were computed to analyze the data. Results: The prevalence of long acting and permanent contraceptive method was 7.3%. Three fourth  (76.1%) of the women have ever heard about implants and implant 28 (50%) were the most widely used method. Almost two third of women had intention to use long acting and permanent methods. Knowledge of contraceptive and age of women have significant association with the use of long acting and permanent contraceptive methods.Conclusion: The overall prevalence of long acting and permanent contraceptive method was low.  Knowledge of contraceptive and age of women have significant association with use of long acting and permanent contraceptive. Extensive health information should be provided.Key words: Long acting, permanent, contraceptive, women, Ethiopi