1,205 research outputs found
STRATEGIC APPROACHES WITH EFFECTS ON COMPETITIVENESS AND PROFITABILITY OF TEXTILE MARKET IN IRAQ
This article contains the results of the research aimed at understanding the effects of the market strategies the textile organizations follow to increase profitability, considering that this sector is a pillar of the national economy. In this respect, 7 hypotheses are stated and verified. This research is an attempt to know how to face competition in this industry.strategic management, competitive market strategy, offensive strategy, defensive strategy, rational strategy, competitiveness, profitability
Prospects for non-immunological molecular therapeutics in melanoma
In 2006 there were 60,000 new cases of cutaneous melanoma in the European Union and 13,000 deaths (www.europeancancerleagues.org). Currently available systemic treatment options for metastatic melanoma, including both cytotoxic and immunologic therapies, produce low rates of response and have modest survival impact. Therefore, there is an urgent need for effective novel therapies. Molecularly targeted treatments have demonstrated efficacy in certain cancers e.g. in HER2-positive breast cancer and in chronic myeloid leukaemia.
Several pathways are currently being investigated as potential molecular targets in melanoma. The best studied is BRAF which is frequently mutated in melanoma. A multi tyrosine kinase inhibitor, sorafenib, which targets BRAF, has shown promising activity in preclinical studies and is currently being tested in combination with chemotherapy in patients with metastatic disease.
In addition to BRAF, therapies which target other components of the Raf/Ras/MAPK pathway are being investigated. Other novel targets currently being investigated include the PI3/AKT pathway, tyrosine kinases, angiogenesis, poly (ADP ribose) polymerases, survivin and heat shock protein 90. Progress on preclinical and clinical evaluation of these novel targets in melanoma will be reviewed
Adaptive Dynamic Inverse Controller for Advanced Coupled Tank Liquid Levels System
Inversion technique has been successfully applied in the tracking control of many Multi Input Multi Output (MIMO) process of engineering as well as science. The difficulty in controller design on account of variations in process dynamics as well as interactions between process variables. In this paper, the combination of neural network and dynamic inversion control is applied in Coupled Tank System (CTS) tracking water level problem. The liquids need to be pumped in total process and stored in the two tanks which are coupled together for certain desired level. Transfer function matrix of the system is gained experimentally from the tension loop response of the system. The PID neural network (PID-NN) controller used as a desired system control. Within MATLAB environment, conduction of simulate experiment is to testify the operation of the system according to Settling Time, Rise Time, Steady State Error and Overshoot. Numerical simulations and experiments have both been conducted to prove the validity of the proposed method. It has been attested that capabilities of CTS are ameliorated by suggested proposed method
Performance, Combustion Characteristics and Emission Tests of Single Cylinder Engine Running on Fusel Oil - Diesel Blended (F20) Fuel
Alcohols produced from a renewable source are amongst the important alternative fuels for internal combustion
engines. Investigations on alternative fuels for compression ignition engines regarded as one of the major research
areas. This paper details an experimental examination of the performance and emissions in single cylinder compression
ignition engines operating with fusel oil F20 and pure diesel F0 at five engine speeds and 50% engine load. The test results indicated that the engine power and torque slightly decrease with the F20 at low speeds compared with pure diesel. Further, the in-cylinder pressure was decreased at all engine speed for F20 in comparison with pure diesel. The volumetric efficiency and fuel consumption were increased for F20 due the low heating value of fusel oil. The results showed that CO2 and CO emissions were increased because of the water content, low heating value and low cetane number for fusel oil. The maximum reduction in NOx emissions was 18% for F20 at 1500 rpm
Performance and Combustion Characteristics of an SI Engine Fueled With Fusel Oil-Gasoline at Different Water Content
The main objective of the current study is to investigate the impacts of fusel oil-gasoline blends with different water content on performance and combustion characteristics of an SI engine. The water content of fusel oil is reduced by employing rotary extractor method. The parameters examined in the current study are the effects of test fuels upon engine performance criteria, fuel combustion, location of CA50 and coefficient of variation of indicated mean effective pressure (COVIMEP). The experiments are conducted in a SI engine with two blending ratio of gasoline-fusel oil (FBWE10 and FAWE10) in addition to pure gasoline as a standard fuel under different engine speeds and constant 45% of WOT engine load. The study results reveal that engine power, torque, and brake thermal efficiency have slightly improved with fusel oil-gasoline blends that were obvious clearly after reduction of water content. On the other hand, though the brake specific fuel consumption of FAWE10 slightly improve compared to FBWE10 but still higher than gasoline. Furthermore, the peak in-cylinder pressure, rate of heat release, and rate of pressure rise enhanced with fusel oil-gasoline blends. The (CA 0–10) and (CA 10–90) duration could be simultaneously decreased by reducing the water content of fusel oil, all of that are helpful to improve the stability of combustion and thought to be reasons for the reduction in COVIMEP. As a conclusion, the reduction of fusel oil water content has played positively to enhance the combustion and performance characteristics of the fuel blend and result in more stable engine operation
Free radical detection in living cells with relaxometry
There is a growing evidence for a correlation between free radicals and the formation of diseases. Free radicals or oxidative stress are expected to be linked to various pathogenic conditions which impact cells. The oxidative stress is a result of an imbalance between reactive oxygen species and antioxidants. In this project we would like to study the free radicals production in living cells, under which condition and where they are generated. We plan to use different cell types to investigate the effect of different mechanism to produce more free radicals in a living cell. We will use a technique called diamond magnetometry, which utilize nano-diamonds to detect free radicals
The Effect of Organization Culture on Organizational Affiliation Field
تعد الثقافة التنظيمية من الاسس المهمة للمنظمة وعلى اختلاف اعمالها , الاهتمام بها يساهم ويدعم في تحقيق اهدافها الفرعية والرئيسية , وكلما سعت ادارة المنظمة على ترسيخها بين العاملين زاد الولاء التنظيمي وبالتالي انعكس هذا على نجاح المنظمة.
وجاء ت هذه الدراسة للتعرف على اثر متغيري الدراسة في تحقيق موقع الدراسة (شركة المحاقن الطبية في محافظة بابل) اهدافها التنظيمية.
وكانت مشكلة الدراسة هو عدم وجود تصور واضح لعينة الدراسة عن اثر الثقافة التنظيمية في الانتماء التنظيمي.
وكانت اهم المقترحات والاستنتاجات هو ضرورة اخذ منظمة الدراسة بعين الاعتبار متغيرات الدراسة بمزيد من الاهتمام وكذلك الاطلاع من خلال الدورات التدريبية على ذلكThe organizational culture of foundations task the and the organization difference their work , the more sought management organization to strengthen the working has increased loyalty organizational thus was reflected this on the success of the organization.
This study was conducted to investigate the effect of the study variable on the study site (medical syringes company in Babylon governorate) organizational objectives.
The problem of the study was the absence a clear perception of the study sample on the effect of organizational affiliation.
The most important suggestion and conclusions were the need for the study organization to consider the variable of the study with more attention and to learn through the training courses on thi
A comprehensive review on the exergy analysis of combined cycle power plants
The arriving optimum improvement of a thermodynamic system of energy conversion such as a combined cycle power plant (CCPP) is complicated due to the existence of different factors. Energy and exergy analysis is utilized as effective methods to determine both the quantity and quality of the energy sources. This paper reviews the latest thermodynamics analysis on each system components of a CCPP independently and determine the exergy destruction of the plant. A few layouts of the CCPP plant from different locations considered as case studies. In fact, the most energy losses occurred in the condenser compared with the plant components. It found that in the combustion chamber (CC) the highest exergy destruction occurred. The ambient temperature causes an evident decrement in the power production by the gas turbine (GT). The result has proved that besides energy, exergy analysis is an efficient way to the assessment of the performance of the CCPP by recommending a more advantageous configuration of the CCPP plant, which would lead to reductions in fuel required and emissions of air pollutants
Differential Mobility Classifiers in the Non-Ideal Assembly
The differential mobility classifier (DMC) is one of the core components in electrical mobility particle sizers for sizing sub-micrometer particles. Designing the DMC requires knowledge of the geometrical and constructional imperfection (or tolerance). Studying the effects of geometrical imperfection on the performance of the DMC is necessary to provide manufacturing tolerance and it helps to predict the performance of geometrically imperfect classifiers, as well as providing a calibration curve for the DMC. This thesis was accomplished via studying the cylindrical classifier and the parallel plate classifier. The numerical model was built using the most recent versions of COMSOL Multiphysics® and MATLAB®.
For the cylindrical DMC, two major geometrical imperfections were studied: the eccentric annular classifying channel and the tilted inner cylinder/rod. For the parallel-plates DMC, the first study examined for the perfectly designed plates to optimize its dimensions and working conditions, while the second study conducted the plates’ parallelism. For both DMCs, a parametric study was conducted for several tolerances under various geometrical factors (i.e., channel length, width, spacing, cylinders radii, etc…), flow conditions (i.e., sheath-to-aerosol flow ratio, total flow rate), and several particles sizes.
The results show that the transfer function deteriorated as the geometrical imperfection increased (i.e., the peak is reduced and the width at the half peak height is broadened). The parallel- plates DMC results show that the aspect ratio of the classifying channel cross-section (width-to-height) was recommended to be above 8. Particle diffusivity reduces the effect of geometrical imperfection, especially for particle sizes less than 10 nm
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