568 research outputs found
The Development of Legal Databases in Refugee Work
Today's information technology can be used to improve the legal protection of refugees, by providing information relevant to the asylum procedure, and laying the foundation for progressive development at the international level. The positive potential of legal databases is only now beginning to be realised, thanks to pioneering efforts within human rights and related documentation centre networks. UNHCR is helping to set up a case law database, in co-operation with non-governmental organizations. A database on national legislation is also planned, as is a full text database of international legal instruments database. Legal literature continues to be covered by the database REFLIT (REFugee LITerature) of UNHCR'S Centre for Documentation on Refugees (CDR/UNHCR). This article examines two basic kinds of information-retrieval systems, ‘free text', and ‘indexed', and considers their different structures, uses and search procedures, with reference to work on a forthcoming refugee thesaurus. The author calls attention to the need for standard formats, such as those of HURIDOCS, and to problems of scope and coverage. He suggests that information and documentation are areas in which practical co-operation between the UN, governments and non-governmental organizations could be implemented to advantag
Performance and Loss Analysis of Squirrel Cage Induction Machine Based Flywheel Energy Storage System
Flywheel energy storage systems (FESS) are one of the earliest forms of energy storage technologies with several benefits of long service time, high power density, low maintenance, and insensitivity to environmental conditions being important areas of research in recent years. This paper focusses on the electrical machine and power electronics, an important part of a flywheel system, the electrical machine rotating with the flywheel inertia in order to perform charge-discharge cycles. The type of machine used in the electrical drive plays an important role in the characteristics governing electrical losses as well as standby losses. Permanent magnet synchronous machine (PMSM) and induction machines (IM) are the two most common types of electric machines used in FESS applications where the latter has negligible standby losses due to its lower rotor magnetic field until energised by the stator. This paper describes research in which the operational and standby losses of a squirrel-cage induction machine-based flywheel storage system (SCIM-FESS) are modelled as a system developed in MATLAB/Simulink environment inclusive of the control system for the power electronics converters. Using the proposed control algorithm and in-depth analysis of the system losses, a detailed assessment of the dynamic performance of the SCIM-FESS is performed for different states of charging, discharging, and standby modes. The results of the analysis show that, in presence of system losses including aerodynamic and bearing friction losses, the SCIM-FESS has satisfactory characteristics in energy regulation and dynamic response during load torque variations. The compliance of FESS and its conversion between the generating and motoring mode within milliseconds show the responsiveness of the proposed control system
Customers' perspectives on the impact of the Pathways to Work Condition Management Programme on their health, wellbeing and vocational activity
Aims: Pathways to Work is a UK initiative aimed at supporting customers on incapacity benefits to return to work. This qualitative study complements previous evaluations of Pathways to Work by exploring customers’ perceptions of the impact of the Condition Management Programme (CMP) offered to claimants with long-term health conditions.
Methods: 39 customers took part in focus groups held at the seven sites where Pathways was originally piloted. The main focus of the discussions was on perceptions of the ways in which participation had impacted on health, well-being and return to work. The discussions were audio-recorded and fully transcribed for analysis using a text analysis framework to enable the development and refinement of categories and overarching patterns in the data.
Results: Perceived impacts on health and wellbeing included a more positive outlook, social contact, changed perceptions of conditions and improvements in health. Some customers also reported an increase in their vocational activity and others felt ready to embark on new activities. Factors associated with positive outcomes included the extent and quality of contact with CMP staff and practical advice about condition management. Factors impeding positive employment outcomes related mainly to obstacles to returning to work.
Conclusions: The results indicated that CMP can assist customers to learn about and manage their health conditions and increase their vocational activity, and that CMP therefore provides a promising means of enabling people with long-term health conditions to regain a fulfilling, productive life
Erzähl mir deine Geschichte : Arten von Storytelling, die in der Ergotherapie Menschen mit psychischen Störungen in der Rehabilitations- oder Integrationsphase unterstützen
Thema: Psychische Störungen sind weltweit verbreitet, führen zu hohen Gesundheitskosten und schränken Betroffene in ihrem Alltag ein. Storytelling-Interventionen können die Lebensqualität von Betroffenen verbessern. In dieser Arbeit wird die mögliche Anwendung von Storytelling in der Ergotherapie erforscht.
Ziel: Zur Anwendung von Storytelling in der Ergotherapie gibt es noch nicht ausreichend Forschung. Deswegen wird in dieser Arbeit auf folgende Frage eingegangen: Welche Arten von Storytelling, die evidenzbasiert bei Menschen mit psychischen Störungen in der Rehabilitations- oder Integrationsphase angewendet werden, eignen sich für ergotherapeutische Interventionen?
Methode: In Datenbanken wurden fünf Studien zu verschiedenen Arten von Storytelling gefunden. Diese wurden zusammengefasst, kritisch gewürdigt und die Ergebnisse der Studien dem Canadian Model of Occupational Performance and Engagement (CMOP-E) gegenübergestellt.
Relevante Ergebnisse: Bei Menschen mit Demenz kann durch TimeSlips und Realitätsorientierung unter anderem die Interaktion verbessert werden. Menschen mit anderen psychischen Störungen können sich durch die Tree Theme Method® und die Foto-Intervention beispielsweise neue Strategien aneignen. Die Transmediale-Intervention würde sich für den Einsatz in der Prävention eignen und ist daher in der Ergotherapie schwieriger anwendbar.
Schlussfolgerung: Anhand der Zuteilung der Ergebnisse zum CMOP-E und der Güte der Studien werden Tree Theme Method®, Realitätsorientierte- und Foto-Intervention für die Ergotherapie mit Menschen mit psychischen Störungen empfohlen
Isolated hypercholesterolemia leads to steatosis in the liver without affecting the pancreas
Abstract Background Lipid accumulation in the liver and pancreas is primarily caused by combined hyperlipidemia. However, the effect of isolated hypercholesterolemia without hypertriglyceridemia is not fully described. Therefore, our aim was to investigate whether hypercholesterolemia alone leads to alterations both in hepatic and pancreatic lipid panel and histology in rats. Methods Male Wistar rats were fed with 2% cholesterol +0.25% cholate-supplemented diet or standard chow for 12 weeks. Blood was collected at weeks 0, 4, 8 and 12 to measure serum cholesterol and triglyceride levels. At week 12, both the pancreas and the liver were isolated for further histological and biochemical analysis. Hepatic and plasma fatty acid composition was assessed by gas chromatography. Expression of mRNA of major enzymes involved in saturated/unsaturated fatty acid synthesis was analyzed by qPCR. In separate experiments serum enzyme activities and insulin levels were measured at week 9. Results At week 12, rats fed with 2% cholesterol +0.25% cholate-supplemented diet were characterized by elevated serum cholesterol (4.09 ± 0.20 vs. 2.89 ± 0.22 mmol/L, *p < 0.05) while triglyceride (2.27 ± 0.05 vs. 2.03 ± 0.03 mmol/L) and glucose levels (5.32 ± 0.14 vs. 5.23 ± 0.10 mmol/L) remained unchanged. Isolated hypercholesterolemia increased hepatic lipid accumulation, hepatic cholesterol (5.86 ± 0.22 vs. 1.60 ± 0.15 ng/g tissue, *p < 0.05) and triglyceride contents (19.28 ± 1.42 vs. 6.78 ± 0.71 ng/g tissue, *p < 0.05), and hepatic nitrotyrosine level (4.07 ± 0.52 vs. 2.59 ± 0.31 ng/mg protein, *p < 0.05). The histology and tissue lipid content of the pancreas was not affected. Serum total protein level, alanine aminotransferase (ALT) and aspartate aminotransferase (AST) activities remained unchanged in response to isolated hypercholesterolemia while serum alkaline phosphatase activity (ALP) significantly increased. Plasma insulin levels did not change in response to isolated hypercholesterolemia suggesting an intact endocrine function of the pancreas. Isolated hypercholesterolemia caused a significantly increased hepatic and serum fatty acid level associated with a marked alteration of fatty acid composition. Hepatic expression of Δ9-desaturase (SCD1) was increased 4.92×, while expression of Δ5-desaturase and Δ6-desaturase were decreased (0.447× and 0.577×, respectively) due to isolated hypercholesterolemia. Conclusions Isolated hypercholesterolemia leads to hepatic steatosis and marked alterations in the hepatic lipid profile without affecting the pancreas. Altered fatty acid profile might mediate harmful effects of cholesterol in the liver
Aldosterone-producing adrenocortical carcinoma with myxoid differentiation in a cat
A 10‐year‐old male neutered Persian cat was presented with an abdominal mass and history of weakness. Blood smear examination found marked elliptocytosis, and serum biochemical analysis revealed hypokalemia, hypochloremia, increased creatine kinase activity, and a high aldosterone concentration. Cytologic examination of the mass revealed neoplastic endocrine cells with moderate criteria of malignancy, favoring adrenocortical neoplasia. The adrenal mass was surgically excised and histologically characterized by lobules of mildly pleomorphic, polygonal neoplastic cells with moderate to abundant, occasionally granular, eosinophilic cytoplasm. Lobules were separated by fine fibrovascular trabeculae, and numerous cystic cavities containing amorphous eosinophilic material that stained positive with Alcian blue and periodic acid‐Schiff were seen. Neoplastic cells were multifocally positive for cytochrome P450 aldosterone synthase. Based on clinicopathologic and immunohistochemical findings the present case was diagnosed as an aldosterone‐producing adrenocortical carcinoma with myxoid differentiation. While this entity has not been reported in cats, myxoid differentiation of adrenocortical carcinomas has been found in other species and can pose a major diagnostic challenge on microscopic examination
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