72 research outputs found
Inversion of provenance data and sediment load into spatially varying erosion rates
Sediment fingerprinting methods aim to determine the relative contribution of different source areas in detrital sediments based on natural properties – fingerprints – of the source areas. Here, we use U/Th–Pb age signatures as fingerprints, assuming that the age signal is not altered during erosion–transportation–deposition events, and given that recent technological advances enable precise dating of large amounts of grains. We introduce a formal inversion method that allows to disentangle the amalgamation of source contributions in detrital zircon data and enables to convert this information into an erosion rate map starting from the spatial distribution of zircon age signatures. Relying on the least‐squares method and using prior and covariance information to deal with non‐uniqueness, we show, using synthetic and natural examples, that we are able to retrieve erosion rate patterns of a catchment when the age distribution and zircon fertility for each source area are well known. Moreover, we show that not only zircon age fingerprints but also other tracers such as mineral content can be used. Furthermore, we found that adding data from samples taken at the outlet of tributaries improves the estimation of erosion rate patterns. We conclude that the least squares inverse model applied to detrital data has great potential for investigating erosion rates
Measurement of stellar age from uranium decay
The ages of the oldest stars in the Galaxy indicate when star formation
began, and provide a minimum age for the Universe. Radioactive dating of
meteoritic material and stars relies on comparing the present abundance ratios
of radioactive and stable nuclear species to the theoretically predicted ratios
of their production. The radioisotope Th (half-life 14 Gyr) has been
used to date Galactic stars, but it decays by only a factor of two over the
lifetime of the Universe. U (half-life 4.5 Gyr) is in principle a more
precise age indicator, but even its strongest spectral line, from singly
ionized uranium at a wavelength of 385.957 nm, has previously not been detected
in stars. Here we report a measurement of this line in the very metal-poor star
CS31082-001, a star which is strongly overabundant in its heavy elements. The
derived uranium abundance, log(U/H) = -13.7+/-0.14+/-0.12 yields an age of
12.5+/-3 Gyr, though this is still model dependent. The observation of this
cosmochronometer gives the most direct age determination of the Galaxy. Also,
with improved theoretical and laboratory data, it will provide a highly precise
lower limit to the age of the Universe.Comment: 3 pages, 1 figure, 1 table, published in Natur
Early and Prolonged Antiretroviral Therapy Is Associated with an HIV-1-Specific T-Cell Profile Comparable to That of Long-Term Non-Progressors
Background: Intervention with antiretroviral treatment (ART) and control of viral replication at the time of HIV-1 seroconversion may curtail cumulative immunological damage. We have therefore hypothesized that ART maintenance over a very prolonged period in HIV-1 seroconverters could induce an immuno-virological status similar to that of HIV-1 long-term non-progressors (LTNPs).Methodology/Principal Findings: We have investigated a cohort of 20 HIV-1 seroconverters on long-term ART (LTTS) and compared it to one of 15 LTNPs. Residual viral replication and reservoirs in peripheral blood, as measured by cell-associated HIV-1 RNA and DNA, respectively, were demonstrated to be similarly low in both cohorts. These two virologically matched cohorts were then comprehensively analysed by polychromatic flow cytometry for HIV-1-specific CD4(+) and CD8(+) T-cell functional profile in terms of cytokine production and cytotoxic capacity using IFN-gamma, IL-2, TNF-alpha production and perforin expression, respectively. Comparable levels of highly polyfunctional HIV-1-specific CD4(+) and CD8(+) T-cells were found in LTTS and LTNPs, with low perforin expression on HIV-1-specific CD8+ T-cells, consistent with a polyfunctional/non-cytotoxic profile in a context of low viral burden.Conclusions: Our results indicate that prolonged ART initiated at the time of HIV-1 seroconversion is associated with immuno-virological features which resemble those of LTNPs, strengthening the recent emphasis on the positive impact of early treatment initiation and paving the way for further interventions to promote virological control after treatment interruption
Specific mutations in H5N1 mainly impact the magnitude and velocity of the host response in mice
Fracture sealing and fluid overpressures in limestones of the Jabal Akhdar dome, Oman mountains
The Nevados de Payachata volcanic region (18°S/69°W, N. Chile)
Subduction-related volcanism in the Nevados de Payachata region of the Central Andes at 18°S comprises two temporally and geochemically distinct phases. An older period of magmatism is represented by glaciated stratocones and ignimbrite sheets of late Miocene age. The Pleistocene to Recent phase (≤0.3 Ma) includes the twin stratovolcanoes Volcan Pomerape and Volcan Parinacota (the Nevados de Payachata volcanic group) and two small centers to the west (i. e., Caquena and Vilacollo). Both stratovolcanoes consist of an older dome-and-flow series capped by an andesitic cone. The younger cone, i. e., V. Parinacota, suffered a postglacial cone collapse producing a widespread debris-avalanche deposit. Subsequently, the cone reformed during a brief, second volcanic episode. A number of small, relatively mafic, satellitic cinder cones and associated flows were produced during the most recent activity at V. Parinacota. At the older cone, i. e., V. Pomerape, an early dome sequence with an overlying isolated mafic spatter cone and the cone-forming andesitic-dacitic phase (mostly flows) have been recognized. The two Nevados de Payachata stratovolcanoes display continuous major- and trace-element trends from high-K 2 O basaltic andesites through rhyolites (53%–76% SiO 2 ) that are well defined and distinct from those of the older volcanic centers. Petrography, chemical composition, and eruptive styles at V. Parinacota differ between pre- and post-debris-avalanche lavas. Precollapse flows have abundant amphibole (at SiO 2 > 59 wt%) and lower Mg numbers than postcollapse lavas, which are generally less silicic and more restricted in composition. Compositional variations indicate that the magmas of the Nevados de Payachata volcanic group evolved through a combination of fractional crystallization, crustal assimilation, and intratrend magma mixing. Isotope compositions exhibit only minor variations. Pb-isotope ratios are relatively low ( 206 Pb/ 204 Pb = 17.95–18.20 and 208 Pb/ 204 Pb = 38.2–38.5); 87 Sr/ 86 Sr ratios range 0.70612–0.70707, 143 Nd/ 144 Nd ratios range 0.51238–0.51230, and γ 18 O SMOW values range from + 6.8% o to + 7.6% o SMOW. A comparison with other Central Volcanic Zone centers shows that the Nevados de Payachata magmas are unusually rich in Ba (up to 1800 ppm) and Sr (up to 1700 ppm) and thus represent an unusual chemical signature in the Andean arc. These chemical and isotope variations suggest a complex petrogenetic evolution involving at least three distinct components. Primary mantle-derived melts, which are similar to those generated by subduction processes throughout the Andean arc, are modified by deep crustal interactions to produce magmas that are parental to those erupted at the surface. These magmas subsequently evolve at shallower levels through assimilation-crystallization processes involving upper crust and intratrend magma mixing which in both cases were restricted to end members of low isotopic contrast.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/47805/1/445_2005_Article_BF01073587.pd
Architecture of the Oman-UAE ophiolite : evidence for a multi-phase magmatic history
The Oman–United Arab Emirates ophiolite is the
world’s largest ophiolite. It is divided into 12 separate faultbounded
blocks, of which the northern three lie wholly or
partly in the United Arab Emirates. Extensive mapping has
shown that the United Arab Emirates blocks contain mantle
and crustal sections which correspond to the classic
‘Penrose conference’ ophiolite definition but which are
cut by a voluminous later magmatic sequence including
ultramafic, mafic and felsic components. Samples from the
later magmatic sequence are dated at 96.4±0.3, 95.74±0.3
and 95.2±0.3 Ma; the early crustal section, which has not
been dated directly, is thus constrained to be older than c.
96.4 Ma. Petrological evidence shows that the early crustal
section formed at a spreading ridge, but the later magmatic
sequence was formed from hydrous magmas that produced
different mineral crystallisation sequences to normal midocean
ridge basalt (MORB). Mineral and whole-rock
geochemical analyses show that the early crustal rocks are
chemically similar to MORB, but the later magmatic
sequence has chemical features typically found in suprasubduction
zone (SSZ) settings. The ophiolite in the United
Arab Emirates thus preserves clear evidence for two stages
of magmatism, an early episode formed at a spreading
centre and a later episode associated with the onset of
subduction. Similar two-stage magmatism has been recognised
in the Oman sector, but the United Arab Emirates
contains the most voluminous SSZ magmatism yet described
from this ophiolite
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