Enhancing Hydrogen Generation Through Nanoconfinement of Sensitizers and Catalysts in a Homogeneous Supramolecular Organic Framework.

Enrichment of molecular photosensitizers and catalysts in a confined nanospace is conducive for photocatalytic reactions due to improved photoexcited electron transfer from photosensitizers to catalysts. Herein, the self-assembly of a highly stable 3D supramolecular organic framework from a rigid bipyridine-derived tetrahedral monomer and cucurbit[8]uril in water, and its efficient and simultaneous intake of both [Ru(bpy)3 ]2+ -based photosensitizers and various polyoxometalates, that can take place at very low loading, are reported. The enrichment substantially increases the apparent concentration of both photosensitizer and catalyst in the interior of the framework, which leads to a recyclable, homogeneous, visible light-driven photocatalytic system with 110-fold increase of the turnover number for the hydrogen evolution reaction

Travelling wave solutions for Kolmogorov-type delayed lattice reaction–diffusion systems

[[abstract]]This work investigates the existence and non-existence of travelling wave solutions for Kolmogorov-type delayed lattice reaction–diffusion systems. Employing the cross iterative technique coupled with the explicit construction of upper and lower solutions in the theory of quasimonotone dynamical systems, we can find two threshold speeds c∗ and c∗ with c∗≥c∗>0. If the wave speed is greater than c∗, then we establish the existence of travelling wave solutions connecting two different equilibria. On the other hand, if the wave speed is smaller than c∗, we further prove the non-existence result of travelling wave solutions. Finally, several ecological examples including one-species, two-species and three-species models with various functional responses and time delays are presented to illustrate the analytical results.[[notice]]補正完畢[[journaltype]]國外[[incitationindex]]SCI[[ispeerreviewed]]Y[[booktype]]紙本[[countrycodes]]GB

Tunable Fano Resonances Based on Two-beam Interference in Microring Resonator

In this paper, a resonant system is demonstrated on silicon-on-insulator wafer to achieve tunable Fano resonances. In this system, the Fano resonance originates from the interference of two beams resonant in the microring resonator. The shapes of the Fano resonances are tunable through controlling the phase difference of the two beams. Both large slope and high extinctionratio (ER) are obtained when the phase difference is 0.5π or 1.5π. Experimental results show that Fano resonances with steep slope and ER over 20 dB are achieved in the whole free spectral range by controlling the microheaters to meet the phase condition

miR-638 is a new biomarker for outcome prediction of non-small cell lung cancer patients receiving chemotherapy.

MicroRNAs (miRNAs), a class of small non-coding RNAs, mediate gene expression by either cleaving target mRNAs or inhibiting their translation. They have key roles in the tumorigenesis of several cancers, including non-small cell lung cancer (NSCLC). The aim of this study was to investigate the clinical significance of miR-638 in the evaluation of NSCLC patient prognosis in response to chemotherapy. First, we detected miR-638 expression levels in vitro in the culture supernatants of the NSCLC cell line SPC-A1 treated with cisplatin, as well as the apoptosis rates of SPC-A1. Second, serum miR-638 expression levels were detected in vivo by using nude mice xenograft models bearing SPC-A1 with and without cisplatin treatment. In the clinic, the serum miR-638 levels of 200 cases of NSCLC patients before and after chemotherapy were determined by quantitative real-time PCR, and the associations of clinicopathological features with miR-638 expression patterns after chemotherapy were analyzed. Our data helped in demonstrating that cisplatin induced apoptosis of the SPC-A1 cells in a dose- and time-dependent manner accompanied by increased miR-638 expression levels in the culture supernatants. In vivo data further revealed that cisplatin induced miR-638 upregulation in the serum derived from mice xenograft models, and in NSCLC patient sera, miR-638 expression patterns after chemotherapy significantly correlated with lymph node metastasis. Moreover, survival analyses revealed that patients who had increased miR-638 levels after chemotherapy showed significantly longer survival time than those who had decreased miR-638 levels. Our findings suggest that serum miR-638 levels are associated with the survival of NSCLC patients and may be considered a potential independent predictor for NSCLC prognosis

Complete sequence of the FII plasmid p42-2, carrying blaCTX-M-55, oqxAB, fosA3, and floR from Escherichia coli

We sequenced a novel conjugative multidrug resistance IncF plasmid, p42-2, isolated from Escherichia coli strain 42-2, previously identified in China. p42-2 is 106,886 bp long, composed of a typical IncFII-type backbone (∼54 kb) and one distinct acquired DNA region spanning ∼53 kb, harboring 12 antibiotic resistance genes [blaCTX-M-55, oqxA, oqxB, fosA3, floR, tetA(A), tetA(R), strA, strB, sul2, aph(3′)-II, and ΔblaTEM-1]. The spread of these multidrug resistance determinants on the same plasmid is of great concern and, because of coresistance to antibiotics from different classes, is therapeutically challenging

Extreme Coronal Line Emitters: Tidal Disruption of Stars by Massive Black Holes in Galactic Nuclei?

Tidal disruption of stars by supermassive black holes at the centers of galaxies is expected to produce unique emission line signatures, which have not yet been explored adequately. Here we report the discovery of extremely strong coronal lines from [Fe X] up to [Fe XIV] in a sample of seven galaxies (including two recently reported cases), that we interpret as such signatures. This is the first systematic search for objects of this kind, by making use of the immense database of the Sloan Digital Sky Survey. The galaxies, which are non-active as evidenced by the narrow-line ratios, show broad emission lines of complex profiles in more than half of the sample. Both the high ionization coronal lines and the broad lines turn out to be fading on time scales of years in objects observed with spectroscopic follow-ups, suggesting their transient nature. Variations of inferred non-stellar continua, which have absolute magnitudes of at least -16 to -18 mag in the g band, are also detected in more than half of the sample. These extreme coronal line emitters reside in sub-L_* disk galaxies (-21.3 < M_i < -18.5) with small stellar velocity dispersions. The sample seems to form two distinct types based on the presence or absence of the [Fe VII] lines, with the latter having relatively low luminosities of [O III], [Fe XI], and the host galaxies. These characteristics can most naturally be understood in the context of transient accretion onto intermediate mass black holes at galactic centers following tidal disruption of stars in a gas-rich environment. We estimate the incidence of such events to be around 10^-5 per year for a galaxy with -21.5 < M_i < -18.5.Comment: 32 pages, 12 figures, ApJ accepted, typos correcte