Investments characteristics in infrastructure industry

The development of the infrastructure has always represented a major priority at the level of all actors implied in the economic-social activity, from public authorities to private organizations and even civil population. The particularities of the investment projects in the infrastructure attract a more and wider private organizations category which analyses the infrastructure differences as potential business opportunities. The present paper presents a series of particularities specific for the investments in the infrastructure sphere as well as the main attraction factor for the private companies.investments, efficiency, infrastructure

Role of Point-of-Care Testing in Reducing Time to Treatment Decision-Making in Urgency Patients: A Randomized Controlled Trial

Introduction: Shortening emergency department (ED) visit time can reduce ED crowding, morbidity and mortality, and improve patient satisfaction. Point-of-care testing (POCT) has the potential to decrease laboratory turnaround time, possibly leading to shorter time to decision-making and ED length of stay (LOS). We aimed to determine whether the implementation of POCT could reduce time to decision-making and ED LOS.Methods: We conducted a randomized control trial at the Urgency Room of Siriraj Hospital in Bangkok, Thailand. Patients triaged as level 3 or 4 were randomized to either the POCT or central laboratory testing (CLT) group. Primary outcomes were time to decision-making and ED LOS, which we compared using Mann-Whitney-Wilcoxon test.Results: We enrolled a total of 248 patients: 124 in the POCT and 124 in the CLT group. The median time from arrival to decision was significantly shorter in the POCT group (106.5 minutes (interquartile [IQR] 78.3-140) vs 204.5 minutes (IQR 165-244), p <0.001). The median ED LOS of the POCT group was also shorter (240 minutes (IQR 161.3-410) vs 395.5 minutes (IQR 278.5-641.3), p <0.001).Conclusion: Using a point-of-care testing system could decrease time to decision-making and ED LOS, which could in turn reduce ED crowding

I, River?: New materialism, riparian non-human agency and the scale of democratic reform

This article is a discussion of the “discourse on the unthinkable” surrounding potential future democratic engagements with rivers as non-human persons or natural objects. In the context of the Asia–Pacific region, this article suggests that the developments in material philosophy entitled “new materialism” are essential tools in the reconceptualisation of rivers as democratic entities but that local socio-historical conditions must also be taken into the account. In order to make its case, the article not only surveys the context for considering rivers as non-human persons in a juridical context but also discusses the new material context that assists modern democracies in the renegotiation of the demos that forms the body politic of democracy – often in the face of neoliberal exploitation and a legacy of extremes in instrumentalism. The article argues that the incorporation of water in the democratic project of enfranchisement is an essential exercise born of many Western beliefs and ideals but articulated uniquely at a regional and national level

Analisis Non-Performing Loan, Capital Adequacy Ratio Dan Loan to Deposit Ratio Terhadap Profitabilitas BPR Kota Batam

Penelitian ini bertujuan untuk menganalisis pengaruh tiga variabel independen, yaitu Non-Performing Loan (NPL), Capital Adequacy Ratio (CAR), dan Loan to Deposit Ratio (LDR), terhadap variabel dependen, yaitu Profitabilitas BPR Kota Batam. Populasi penelitian ini adalah seluruh Bank Perkreditan Rakyat (BPR) yang terdaftar di Otoritas Jasa Keuangan (OJK) di Kota Batam pada tahun 2019-2022. Jumlah sampel yang diambil adalah 81, dengan metode pengambilan sampel purposive random sampling. Data yang digunakan dalam penelitian ini adalah data sekunder yang bersumber dari laporan keuangan BPR Batam selama periode penelitian yang ditentukan. Tipe data yang digunakan adalah data time series. Metode analisis yang digunakan adalah analisis regresi linier berganda dengan menggunakan software SPSS versi 26. Kesimpulan dari penelitian ini adalah terdapat pengaruh negatif yang signifikan dari Non-Performing Loan terhadap Profitabilitas pada BPR di Batam. Non-Performing Loan (NPL), kemudian ditemukan pengaruh yang signifikan terhadap Rasio Kecukupan Modal terhadap Profitabilitas pada BPR di Batam, dilanjutkan dengan tidak adanya pengaruh terhadap loan to deposit ratio terhadap profitabilitas BPR di Batam, temuan juga menyimpulkan bahwa terdapat pengaruh yang signifikan terhadap Non Performing Loan, Capital Adequacy Ratio dan Loan to Deposit Ratio terhadap Profitabilitas BPR di Batam.Kata kunci: capital adequacy ratio, loan to deposit ratio, non-performing loan, .profitabilitas

Article Review: The Elusive Green Consumer: Authors: Katherine White, David J. Hardisty, and Rishad Habib Harvard Business Review, July - August 2019

Going green and sustainable has been a frustrating paradox to companies for decades. Consumers are often considered as the biggest hurdle to companies when going green and sustainable. Most consum­ers claim to be eco-friendly, but in actual fact their green consumption patterns are constrained by other priorities in life, reflecting an intention-action gap. This article, “The Elusive Green Consumer” by White, K., Hardisty, D. J., & Habib, R. (2019) inspires readers of the Harvard Business Review with a comprehensive insight into green consumption and sustainable behavior throughout its 17 pages. &nbsp

Increasing the healing rate of skin wounds

No abstract

Altered CD94/NKG2A and perforin expression reduce the cytotoxic activity in malignant pleural effusions

CD94/NKG2A is an inhibitory receptor expressed by NK cells and cytotoxic lymphocytes and, upon activation by HLA-E, downregulates the cytolytic activities of these cells thus representing a tumour immune escape mechanism. This study was aimed at assessing whether cytotoxic lymphocytes (CD8+) and NK cells from malignant pleural effusions have a deregulated expression of CD94/NKG2A. The expression of membrane CD94/NKG2A and perforin was evaluated by flow-cytometry in CD8+ and NK cells from pleural effusions and autologous peripheral blood of cancer (n=19) and congestive heart failure (CHF) (n=11) patients. Intracellular CD94/NKG2A expression was evaluated by flow-cytometry in pleural effusion CD8+ and NK cells from cancer patients (n=10). Cytotoxic activity against cancer cells exerted by pleural and autologous peripheral blood T lymphocytes from cancer patients was assessed by flow-cytometry assay. Pleural CD8+ from cancer patients showed a reduced expression of membrane CD94/NKG2A and perforin when compared to autologous peripheral blood and CHF pleural effusions. Reduced numbers of NK cells were present in pleural effusions from both cancer and CHF patients. Pleural NK from cancer patients showed a reduced expression of membrane CD94/NKG2A and perforin when compared to autologous peripheral blood. Pleural T lymphocytes from cancer patients exhibited a reduced cytotoxic activity against cancer cells when compared to autologous peripheral blood T lymphocytes. The intracellular expression of CD94/NKG2A in CD8+ and NK cells from cancer patients was higher than membrane expression. In conclusion, this study provides compelling evidences of new mechanisms underlying the reduced host defence against cancer within the pleural space

PENGARUH BIAYA PRODUKSI, BIAYA PROMOSI DAN VOLUME PENJUALAN TERHADAP LABA PADA PERUSAHAAN MANUFAKTUR YANG TERDAFTAR DI BURSA EFEK INDONESIA

This study aims toidetermine theieffect of production costs, promotionicosts andisales volume on profits in manufacturing companies listed on the Indonesia Stock Exchange for the period 2013-2017. The population inithis study is aicompany found in theiconsumer goods industry sector listed on theiIndonesia StockiExchange. The samplingitechnique uses purposive sampling. Theidependent variable in this study is profit. Independentivariables include: production costs, promotionicosts and sales volume. The analyticalimethod used is a multipleilinear regressionianalysis method using SPSS (Statistical Product andiService Solution) version 22. The sample used is 40 financial reports from 8 consumptionisector manufacturingicompaniesilisted on theiIndonesia StockiExchange. The sampleican be based on the following criteria: (1) Manufacturing companies of the consumer goods industry sector listed on the Indonesia StockiExchange from 2013-2017. (2) Data taken is financial statements in rupiah. (3) Availability and completeness of data during the period 2013-2017. The results showed that productionicosts and promotion costs did not significantly influence earnings, while sales volumeihad a significant effect on earnings

Article Review: Digital Doesn’t Have to Be Disruptive

Digital Doesn’t Have to Be DisruptiveAuthors: Nathan Furr and Andrew ShipilovHarvard Business Review:July - August 2019 Issue, pp. 94 - 10