Galactic cosmic ray exposure estimates for SAGE-3 mission in polar orbit

An analysis of the effects of galactic cosmic ray (GCR) exposures on charge-coupled devices (CCDs) was performed for the SAGE-III 5-year mission in sun-synchronous orbit between 1996 and 2001. A detailed environment model used in conjunction with a geomagnetic vertical cut-off code provides the predicted 5-year fluence of GCR ions. A computerized solid model of the spacecraft was used to define the effective shield thickness distribution around the CCD detector. The particle fluences at the detector location are calculated with the Langley heavy-ion transport code, and these fluences are used in conjunction with estimated nuclear stopping powers to evaluate dosimetric quantities related to the detector degradation. A previous study analyzing effects of trapped particle and solar flare protons indicated an approximate 20 percent reduction in detector sensitivity for the mission. The galactic cosmic ray contribution was thought to be relatively small and therefore was not previously analyzed. The present study provides quantification of the GCR effects, which are found to contribute less than 1 percent of the total environment degradation

Southeast.

This bulletin reports on Department of Agricultural Economics Research Project 167, Dairy Industry Development--P. [2].Digitized 2007 AES.Includes bibliographical references (page [40])

Computationally-Driven Experimental Discovery of the CeIr4_4In Compound

We present a combined experimental and computational methodology for the discovery of new materials. Density functional theory (DFT) formation energy calculations allow us to predict the stability of various hypothetical structures. We demonstrate this approach by computationally predicting the Ce-Ir-In ternary phase diagram. We predict previously-unknown compounds CeIr$_4$In and Ce$_2$Ir$_2$In to be stable. Subsequently, we successfully synthesize CeIr$_4$In and characterize it by X-ray diffraction. Magnetization and heat capacity measurements of CeIr$_4$In are reported. The correct prediction and discovery of CeIr$_4$In validates this approach for discovering new materials

Parity-violating Electron Deuteron Scattering and the Proton's Neutral Weak Axial Vector Form Factor

We report on a new measurement of the parity-violating asymmetry in quasielastic electron scattering from the deuteron at backward angles at Q2= 0.038 (GeV/c)2. This quantity provides a determination of the neutral weak axial vector form factor of the nucleon, which can potentially receive large electroweak corrections. The measured asymmetry A=-3.51 +/- 0.57(stat) +/- 0.58(sys)ppm is consistent with theoretical predictions. We also report on updated results of the previous experiment at Q2=0.091 (GeV/c)2, which are also consistent with theoretical predictions.Comment: 4 pages, 2 figures, submitted to Phys. Rev. Let

Final results for the neutron β-asymmetry parameter A₀ from the UCNA experiment

The UCNA experiment was designed to measure the neutron β-asymmetry parameter A0 using polarized ultracold neutrons (UCN). UCN produced via downscattering in solid deuterium were polarized via transport through a 7 T magnetic field, and then directed to a 1 T solenoidal electron spectrometer, where the decay electrons were detected in electron detector packages located on the two ends of the spectrometer. A value for A0 was then extracted from the asymmetry in the numbers of counts in the two detector packages. We summarize all of the results from the UCNA experiment, obtained during run periods in 2007, 2008–2009, 2010, and 2011–2013, which ultimately culminated in a 0.67% precision result for A₀

Tetraspanin (TSP-17) Protects Dopaminergic Neurons against 6-OHDA-Induced Neurodegeneration in <i>C. elegans</i>

Parkinson's disease (PD), the second most prevalent neurodegenerative disease after Alzheimer's disease, is linked to the gradual loss of dopaminergic neurons in the substantia nigra. Disease loci causing hereditary forms of PD are known, but most cases are attributable to a combination of genetic and environmental risk factors. Increased incidence of PD is associated with rural living and pesticide exposure, and dopaminergic neurodegeneration can be triggered by neurotoxins such as 6-hydroxydopamine (6-OHDA). In C. elegans, this drug is taken up by the presynaptic dopamine reuptake transporter (DAT-1) and causes selective death of the eight dopaminergic neurons of the adult hermaphrodite. Using a forward genetic approach to find genes that protect against 6-OHDA-mediated neurodegeneration, we identified tsp-17, which encodes a member of the tetraspanin family of membrane proteins. We show that TSP-17 is expressed in dopaminergic neurons and provide genetic, pharmacological and biochemical evidence that it inhibits DAT-1, thus leading to increased 6-OHDA uptake in tsp-17 loss-of-function mutants. TSP-17 also protects against toxicity conferred by excessive intracellular dopamine. We provide genetic and biochemical evidence that TSP-17 acts partly via the DOP-2 dopamine receptor to negatively regulate DAT-1. tsp-17 mutants also have subtle behavioral phenotypes, some of which are conferred by aberrant dopamine signaling. Incubating mutant worms in liquid medium leads to swimming-induced paralysis. In the L1 larval stage, this phenotype is linked to lethality and cannot be rescued by a dop-3 null mutant. In contrast, mild paralysis occurring in the L4 larval stage is suppressed by dop-3, suggesting defects in dopaminergic signaling. In summary, we show that TSP-17 protects against neurodegeneration and has a role in modulating behaviors linked to dopamine signaling

First Measurement of the Neutron β\beta-Asymmetry with Ultracold Neutrons

We report the first measurement of angular correlation parameters in neutron $\beta$-decay using polarized ultracold neutrons (UCN). We utilize UCN with energies below about 200 neV, which we guide and store for $\sim 30$ s in a Cu decay volume. The $\vec{\mu}_n \cdot \vec{B}$ potential of a static 7 T field external to the decay volume provides a 420 neV potential energy barrier to the spin state parallel to the field, polarizing the UCN before they pass through an adiabatic fast passage (AFP) spin-flipper and enter a decay volume, situated within a 1 T, $2 \times 2\pi$ superconducting solenoidal spectrometer. We determine a value for the $\beta$-asymmetry parameter $A_0$, proportional to the angular correlation between the neutron polarization and the electron momentum, of $A_0 = -0.1138 \pm 0.0051$.Comment: 4 pages, 2 figures, 1 table, submitted to Phys. Rev. Let