Power sector reform and goverance in west and central Africa

Thesis(Master) --KDI School:Master of Development Policy,2014masterpublishedTokam Bobino Franklin

The African Landscape through Space and Time

It is generally accepted that Cenozoic epeirogeny of the African continent is moderated by convective circulation of the mantle. Nevertheless, the spatial and temporal evolution of Africa's “basin-and-swell” physiography is not well known. Here we show how continental drainage networks can be used to place broad constraints on the pattern of uplift through space and time. First, we assemble an inventory of 710 longitudinal river profiles that includes major tributaries of the 10 largest catchments. River profiles have been jointly inverted to determine the pattern of uplift rate as a function of space and time. Our inverse model assumes that shapes of river profiles are controlled by uplift rate history and modulated by erosional processes, which can be calibrated using independent geologic evidence (e.g., marine terraces, volcanism and thermochronologic data). Our results suggest that modern African topography started to develop ∼30 Myr ago when volcanic swells appeared in North and East Africa. During the last 15–20 Myr, subequatorial Africa was rapidly elevated, culminating in the appearance of three large swells that straddle southern and western coasts. Our results enable patterns of sedimentary flux at major deltas to be predicted and tested. We suggest that the evolution of drainage networks is dominated by rapid upstream advection of signals produced by a changing pattern of regional uplift. An important corollary is that, with careful independent calibration, these networks might act as useful tape recorders of otherwise inaccessible mantle processes. Finally, we note that there are substantial discrepancies between our results and published dynamic topographic predictions

Hélène Yinda’s African Feminist Approach to Liberation Theology

Hélène Yinda, a matriarch from French speaking Cameroon, advocates for the liberation of African women with succinct evidence why they deserve a Nobel peace prize as opposed to other continents. She argues that sexual difference promotes women’s human rights and liberates their creative energy in the context of hegemonic masculinity. According to Yinda, before the spread of the gospel in Africa, Africa had their own indigenous cultures, lifestyle and hospitality. Although the Christian gospel is perceived to have originated from the West, it was not an ideology to be imposed on Africans. The use of the African feminist theoretical framework of inclusiveness, collaboration and negotiation will be used to explain her quest for an ecumenical movement to transform the world. As such, Christians should be united to accept difference. The concept of difference and ecumenism educates people to be creative, thoughtful, reflective and imagine initiatives to liberate themselves from crisis - achievable only through a grand world movement willing to help local institutions. The bottom line is that this new gospel or ecumenism must not lose sight of Africa’s contribution. Fur- thermore, Hélène Yinda advocates for the eradication of gender inequalities, such as gender-based violence, injustices, stereotypes, prejudices against African women and traditions, which degrades and enslaves women due to ignorance and fear. This research is historical, descriptive and qualitative and will answer the following questions: How has Hélène Yinda’s research changed African theology, address feminism and improve on the rights of African women? What are the cultural and religious context that motivates her works? What are the sources of her findings, which led to her quest for ecumenism and gender equality? These and other similar questions will be answered with the view of unfolding a liberating theology of the French Speaking Matriarch- Hélène Yinda

Comparative Study on Load Monitoring Approaches

Without an appropriate monitoring system, the condition/state of electrical appliances/devices in operation in households cannot be fully assessed, resulting in uncontrolled expenses. The purpose of load monitoring techniques is to save electricity consumption. With proper controls, overconsumption of energy can be reduced and unwanted activity that can lead to unnecessary electricity consumption can be eliminated. To achieve this, two approaches are used. The first approach, which says that each device is monitored by means of individual meters or metering devices, is called intrusive load monitoring (ILM) and requires expensive deployment of metering devices for its use. In contrast to the first one, the second approach is non-intrusive load monitoring (NILM), which monitors electricity consumption without the need for any intrusion. In this configuration, the total energy consumed is disaggregated into the individual consumption of each load. With progress/advances in artificial intelligence, this approach is gaining interest with influences in other areas of research. Knowing that these developed techniques aim to encourage the occupants of dwellings to save energy by optimizing their electricity consumption, the paper presents a comparative study of these approaches, in order to highlight the strengths as well as the weaknesses of each of them. It is therefore a means of offering researchers the opportunity to make choices according to the orientations given to the research work

Synergistic Antibiofilm Efficacy of Thymol and Piperine in Combination with Three Aminoglycoside Antibiotics against Klebsiella pneumoniae Biofilms

Background. Thymol and piperine are two naturally occurring bioactive compounds with several pharmacological activities. In this study, their antibiofilm potential either alone or in combination with three aminoglycoside antibiotics was evaluated against a biofilm of Klebsiella pneumoniae. Methods. Determination of antimicrobial susceptibility was performed using the broth microdilution method. Biofilm formation was evaluated by the microtiter plate method. Antibiofilm activity was determined using 3-(4, 5-dimethyl-2-thiazolyl)-2, 5-diphenyl-2H-tetrazolium-bromide (MTT) assay. The combination studies were performed by the checkerboard microdilution method. Results. The minimum biofilm inhibitory concentration (MBIC) of streptomycin was reduced by 16- to 64-fold when used in combination with thymol, while the MBIC of kanamycin was reduced by 4-fold when combined with piperine. The minimum biofilm eradication concentration (MBEC) values of streptomycin, amikacin, and kanamycin were, respectively, 16- to 128-fold, 4- to 128-fold, and 8- to 256-fold higher than the planktonic minimum inhibitory concentration (MIC). Thymol combined with streptomycin or kanamycin showed synergic effects against the preformed biofilm with 16- to 64-fold reduction in the minimum biofilm eradication concentration values of each antibiotic in combination. Piperine acted also synergically with kanamycin with an 8- to 16-fold reduction in the minimum biofilm eradication concentration values of kanamycin in combination. Conclusion. The association of thymol with antibiotics showed a strong synergistic effect both in the inhibition of biofilm formation and the destruction of the preformed biofilm of K. pneumoniae. This study suggests that a combination of thymol with streptomycin, amikacin, or kanamycin could be a promising alternative therapy to overcome the problem of K. pneumoniae biofilm-associated infections

Synergistic Antibiofilm Efficacy of Thymol and Piperine in Combination with Three Aminoglycoside Antibiotics against Klebsiella pneumoniae Biofilms

Background. Thymol and piperine are two naturally occurring bioactive compounds with several pharmacological activities. In this study, their antibiofilm potential either alone or in combination with three aminoglycoside antibiotics was evaluated against a biofilm of Klebsiella pneumoniae. Methods. Determination of antimicrobial susceptibility was performed using the broth microdilution method. Biofilm formation was evaluated by the microtiter plate method. Antibiofilm activity was determined using 3-(4, 5-dimethyl-2-thiazolyl)-2, 5-diphenyl-2H-tetrazolium-bromide (MTT) assay. The combination studies were performed by the checkerboard microdilution method. Results. The minimum biofilm inhibitory concentration (MBIC) of streptomycin was reduced by 16- to 64-fold when used in combination with thymol, while the MBIC of kanamycin was reduced by 4-fold when combined with piperine. The minimum biofilm eradication concentration (MBEC) values of streptomycin, amikacin, and kanamycin were, respectively, 16- to 128-fold, 4- to 128-fold, and 8- to 256-fold higher than the planktonic minimum inhibitory concentration (MIC). Thymol combined with streptomycin or kanamycin showed synergic effects against the preformed biofilm with 16- to 64-fold reduction in the minimum biofilm eradication concentration values of each antibiotic in combination. Piperine acted also synergically with kanamycin with an 8- to 16-fold reduction in the minimum biofilm eradication concentration values of kanamycin in combination. Conclusion. The association of thymol with antibiotics showed a strong synergistic effect both in the inhibition of biofilm formation and the destruction of the preformed biofilm of K. pneumoniae. This study suggests that a combination of thymol with streptomycin, amikacin, or kanamycin could be a promising alternative therapy to overcome the problem of K. pneumoniae biofilm-associated infections.</jats:p

Hybrid HDBSCAN-FHMM Approach for Energy Disaggregation in Non-Intrusive Load Monitoring (NILM) Systems

Non-intrusive load monitoring (NILM) is emerging as a useful approach to improving the energy efficiency of buildings and households, particularly in the face of the growing challenges of environmental sustainability. Despite recent advances, the accuracy and reliability of disaggregation algorithms remain limited by the diversity of household energy behaviors and the heterogeneous operation of domestic appliances. In this study, we propose a method based on the prior identification of appliance operating states using the HDBSCAN (Hierarchical Density-Based Spatial Clustering of Application with Noise) algorithm, prior to the disaggregation of overall energy consumption. Our study is based on the AMPds dataset (Almanac of Minutely Power Dataset), which provides detailed measurements of residential power consumption. Our methodology consisted of two main phases: an appliance operating state identification phase using the HDBSCAN algorithm, followed by an energy disaggregation phase based on a modified FHMM (Factorial Hidden Markov Model). The model&#x2019;s performance was evaluated using three main metrics: F1 score, Mean Absolute Error (MAE) and Match Rate, in comparison with several reference models including the Adaptive-FHMM. The results obtained show that our HDBSCAN-FHMM model outperforms several models of energy disaggregation algorithms, but also the Adaptive-FHMM reference approach, with significant improvements of 6.25%, 46.24% and 12.04% for the F1, MAE and Match Rate metrics respectively. These performances reinforce the reliability of our method in accurately attributing the energy consumption of household appliances. Nevertheless, challenges remain, particularly with regard to model robustness in the face of variability in energy behavior and technological evolution. Future exploration of deep learning techniques combined with current methods could offer significant advances in energy disaggregation

Synergistic Antibiofilm Effect of Thymol and Piperine in Combination with Aminoglycosides Antibiotics against Four Salmonella enterica Serovars

Biofilms related to human infection have high levels of pathogenicity due to their resistance to antimicrobial agents. The discovery of antibiofilm agents is necessary. One approach to overcome this problem is the use of antibiotics agents’ combination. This study aimed to determine the efficacy of the combination of natural products thymol and piperine with three aminoglycosides antibiotics, amikacin, kanamycin, and streptomycin against biofilm-forming Salmonella enterica. The microtiter plate assay method was used to evaluate the biofilm-producing capacity of the isolates. Minimum inhibitory concentration (MIC) and minimum bactericidal concentration were determined by the broth microdilution method. The inhibition of biofilm formation and biofilm eradication was determined using the microtiter broth method. The checkerboard method was used to determine the combined effects of natural products with aminoglycosides antibiotics. All the tested isolates showed various levels of biofilm formation. Overall, combinations provided 43.3% of synergy in preventing the biofilm formation and 40% of synergy in eradicating preformed biofilms, and in both cases, no antagonism was observed. The combination of thymol with kanamycin showed a synergistic effect with 16- to 32-fold decrease of the minimum biofilm eradication concentration (MBEC) of kanamycin. The interaction of piperine with amikacin and streptomycin also revealed a synergistic effect with 16-fold reduction of the minimum biofilm inhibitory concentration (MBIC). The combination of thymol with the three antibiotics showed a strong synergistic effect in both inhibiting the biofilm formation and eradicating the preformed biofilm. This study demonstrates that thymol and piperine potentiate the antibiofilm activity of amikacin, kanamycin, and streptomycin. These combinations are a promising approach therapeutic to overcome the problem of Salmonella enterica biofilm-associated infections. In addition, these combinations could help reduce the concentration of individual components, thereby minimizing the nephrotoxicity of aminoglycosides antibiotics.</jats:p

Combination of Terrestrial and Satellite Gravity Data for the Characterization of the Southwestern Coastal Region of Cameroon: Appraisal for Hydrocarbon Exploration

The southwestern coastal region of Cameroon is an area of interest because of its hydrocarbon potential (gas and oil). Terrestrial and satellite gravity data were combined and analyzed to provide a better precision in determining the structure of the study area. Firstly, the two gravity databases (in situ and satellite) have been coupled and validated using the least square collocation technique. Then, spectral analysis was applied to the combined Bouguer anomaly map to evaluate the thickness of sediments in some localities. We found that the sedimentary cover of the southwestern coastal region of Cameroon has a thickness that varies laterally from 1.68 ± 0.08 to 2.95 ± 0.15   km , especially in the western part. This result confirms that our target area is a potential site for hydrocarbon exploration. The horizontal gradient method coupled with the upward continuation at variable heights has been used to highlight several lineaments and their directions (N-S, E-W, SW-NE, and SSW-NNE). Lineaments trending in an N-S orientation are predominant. The Euler deconvolution method was also applied to the Bouguer anomaly map to determine the position, orientation, and depth of the different superficial faults of the study area. It appears that the majority of superficial faults have an N-S and SSW-NNE orientation. These directions are correlated with those previously highlighted by the maxima of horizontal gradient. The structural map could be used for a better identification of the direction of fluid flow within the subsurface or to update the geological map of our study area.</jats:p