Viral-skiによるドミナントネガティブなRb転写抑制に対する阻害作用

Thesis (Ph. D. in Medical Science)--University of Tsukuba, (A), no. 2154, 1999.3.25Joint authors: Teruaki Nomura ... et al.Offprint. Originally published in: The journal of biological chemistry, v. 274, no. 8, pp. 4485-4488, 1999Includes supplementary treatise

Measuring and structuring the spatial coherence length of organic light-emitting diodes

This work was supported by the Engineering and Physical Science Research Council (EPSRC) grants “Challenging the limits of photonics: structured light” EP/J01771X and “Ultra-parallel visible light communications” EP/K00042X. IDWS and KD also acknowledge Royal Society Wolfson Research Merit awards.The spatial coherence of organic light-emitting diodes (OLEDs) is an important parameter that has gained little attention to date. Here we present a method for making quantitative measurements of the spatial coherence of OLEDs using a Young’s double-slit experiment. The usefulness of the method is demonstrated by making measurements on a range of OLEDs with different emitters (iridium and europium complexes) and architectures (bottom- and top-emitting) and the fringe visibility is further manipulated by gratings embedded in external diffractive optical elements. Based on the experiments and simulation of the results, we quantitatively determine the spatial coherence lengths of several OLEDs and find them to be a few micrometers. A 60% increase in the spatial coherence length was observed when using a narrow bandwidth emitter and a metal-coated grating.Publisher PDFPeer reviewe

Room temperature triplet state spectroscopy of organic semiconductors

Organic light-emitting devices and solar cells are devices that create, manipulate, and convert excited states in organic semiconductors. It is crucial to characterize these excited states, or excitons, to optimize device performance in applications like displays and solar energy harvesting. This is complicated if the excited state is a triplet because the electronic transition is ‘dark’ with a vanishing oscillator strength. As a consequence, triplet state spectroscopy must usually be performed at cryogenic temperatures to reduce competition from non-radiative rates. Here, we control non-radiative rates by engineering a solid-state host matrix containing the target molecule, allowing the observation of phosphorescence at room temperature and alleviating constraints of cryogenic experiments. We test these techniques on a wide range of materials with functionalities spanning multi-exciton generation (singlet exciton fission), organic light emitting device host materials, and thermally activated delayed fluorescence type emitters. Control of non-radiative modes in the matrix surrounding a target molecule may also have broader applications in light-emitting and photovoltaic devices.United States. Dept. of Energy. Center for Excitonics (Award DE-SC0001088

Efficient and Flexible Checkpoint/Restore of Split-memory Virtual Machines

Recently, clouds provide virtual machines (VMs) with a large amount of memory for big data analysis. For easier migration of such VMs, split migration divides the memory of a VM into several pieces and transfers them to multiple hosts. Since the migrated VM called a split-memory VM needs to exchange memory data between the hosts, it is inherently subject to host and network failures. As a countermeasure, a checkpoint/restore mechanism has been used to periodically save the state of a VM, but the traditional mechanism is not suitable for split-memory VMs. It has to move a large amount of memory data between hosts during checkpointing and can just restores a normal VM on one host. This paper proposes D-CRES for efficient and flexible checkpoint/restore of split-memory VMs. D-CRES achieves fast checkpointing by saving the memory of a VM in parallel at all the hosts without moving memory data. For live checkpointing, it consistently saves the memory of a running VM by considering memory data exchanged by the VM itself. In addition, it enables a split-memory VM to be restored in parallel at multiple hosts. We have implemented checkpoint/restore of D-CRES in KVM and showed that the performance was up to 5.4 times higher than that of using the traditional mechanism.2020 International Conference on Computational Intelligence (ICCI), 8-9 October, 2020, Universiti Teknologi PETRONAS (UTP), Bandar Seri Iskandar, Malaysia（オンライン開催に変更

Photoinduced absorption and photoluminescence in poly(2,5-dimethoxy-p- phenylene vinylene)

We report a study of the photoexcited states in the conjugated polymer poly(2,5-dimethoxy-p-phenylene vinylene). Photoluminescence due to radiative recombination of singlet excitons is observed at energiesjust below the onset of the pi-pi* absorption band at 2.1 eV. Photoinduced absorption at 80 K shows bands peaking at 0.68, 1.35, and 1.80 eV. The features at 0.68 and 1.8 eV are associated with the same excited state which we propose is a doubly charged bipolaron, while the third at 1.35 eV is unrelated. We assign this 1.35-eV absorption to a triplet-triplet transition of a triplet exciton. The bipolarons are long lived with significant numbers surviving in excess of 100 ms at 80 K, and have a weak temperature dependence such that photoinduced absorption is readily detectable even at room temperature. The triplet exciton has a lifetime of order 2.5 ms at 80 K but this falls rapidly at higher temperature and the response is not detected at room temperature. We contrast these results with those obtained previously for the related poly(arylene vinylene) polymers poly(p-phenylene vinylene), and poly(2,5-thienylene vinylene) and for other conjugated polymers, and draw attention to the important role played in the photophysics of these materials by neutral excited states

Transmission scheduling for tandemly-connected sensor networks with heterogeneous packet generation rates

A tandemly-connected multi-hop wireless sensor network model is studied. Each node periodically generates packets in every cycle and relays the packets in a store-and-forward manner on a lossy wireless link between two adjacent nodes. To cope with a considerable number of packet losses, we previously proposed a packet transmission scheduling framework, in which each node transmits its possessing packets multiple times according to a static time-slot allocation to recover or avoid packet losses caused either by physical conditions on links or by interference of simultaneous transmissions among near-by nodes. However, we assumed that the packet generation rate is identical over all nodes, which is not always realistic. Therefore, in this paper, we enhance our work to the case of heterogeneous packet generation rates. We derive a static time-slot allocation maximizing the probability of delivering all packets within one cycle period. By using an advanced wireless network simulator, we show its effectiveness and issues to be solved.12th International Workshop on Information Network Design (WIND-2020), in conjunction with 12th International Conference on Intelligent Networking and Collaborative Systems (INCoS-2020), August 31st - September 2nd, 2020, University of Victoria, Canada（新型コロナ感染拡大に伴い、現地開催中止

Primary ciliary dyskinesia in a Japanese woman caused by a novel RSPH4A variant

Primary ciliary dyskinesia (PCD) is a rare genetic disorder characterized by ciliary dysfunction. We report the case of a 50-year-old Japanese woman with chronic cough, sinusitis, hearing loss, and bronchiectasis. High-speed video analysis of the nasal mucosa revealed reduced ciliary beat frequency and amplitude. Electron microscopy revealed normal cilia mixed with cilia lacking central microtubules. Genetic testing identified a homozygous RSPH4A variant (NM_001010892.3: c.1484C > A). RSPH4A variants account for approximately 3–4 % and A variant.Respiratory Investigation, 63(4), pp.507-509; 2025journal articl