3,014 research outputs found

    Category measures on Baire spaces

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    The purpose of this paper is to give a necessary and sufñcient condition to define a category measure on a Baire topological space. In the last section we give some examples of spaacs in these conditions

    Category measures on Baire spaces

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    The purpose of this paper is to give a necessary and sufñcient condition to define a category measure on a Baire topological space. In the last section we give some examples of spaacs in these conditions

    Maternal urinary metabolic signatures of fetal growth and associated clinical and environmental factors in the INMA study

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    Background Maternal metabolism during pregnancy is a major determinant of the intra-uterine environment and fetal outcomes. Herein, we characterize the maternal urinary metabolome throughout pregnancy to identify maternal metabolic signatures of fetal growth in two subcohorts and explain potential sources of variation in metabolic profiles based on lifestyle and clinical data. Methods We used 1H nuclear magnetic resonance (NMR) spectroscopy to characterize maternal urine samples collected in the INMA birth cohort at the first (n = 412 and n = 394, respectively, in Gipuzkoa and Sabadell cohorts) and third trimesters of gestation (n = 417 and 469). Metabolic phenotypes that reflected longitudinal intra- and inter-individual variation were used to predict measures of fetal growth and birth weight. Results A metabolic shift between the first and third trimesters of gestation was characterized by 1H NMR signals arising predominantly from steroid by-products. We identified 10 significant and reproducible metabolic associations in the third trimester with estimated fetal, birth, and placental weight in two independent subcohorts. These included branched-chain amino acids; isoleucine, valine, leucine, alanine and 3 hydroxyisobutyrate (metabolite of valine), which were associated with a significant fetal weight increase at week 34 of up to 2.4 % in Gipuzkoa (P < 0.005) and 1 % in Sabadell (P < 0.05). Other metabolites included pregnancy-related hormone by-products of estrogens and progesterone, and the methyl donor choline. We could explain a total of 48–53 % of the total variance in birth weight of which urine metabolites had an independent predictive power of 12 % adjusting for all other lifestyle/clinical factors. First trimester metabolic phenotypes could not predict reproducibly weight at later stages of development. Physical activity, as well as other modifiable lifestyle/clinical factors, such as coffee consumption, vitamin D intake, and smoking, were identified as potential sources of metabolic variation during pregnancy. Conclusions Significant reproducible maternal urinary metabolic signatures of fetal growth and birth weight are identified for the first time and linked to modifiable lifestyle factors. This novel approach to prenatal screening, combining multiple risk factors, present a great opportunity to personalize pregnancy management and reduce newborn disease risk in later life

    Independent ferroelectric contributions and rare-earth-induced polarization reversal in multiferroic TbMn2O5

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    Three independent contributions to the magnetically induced spontaneous polarization of multiferroic TbMn2O5 are uniquely separated by optical second harmonic generation and an analysis in terms of Landau theory. Two of them are related to the magnetic Mn3+/4+ order and are independent of applied fields of up to 7 T. The third contribution is related to the long-range antiferromagnetic Tb3+ order. It shows a drastic decrease upon the application of a magnetic field and mediates the change of sign of the spontaneous electric polarization in TbMn2O5. The close relationship between the rare-earth long-range order and the non-linear optical properties points to isotropic Tb-Tb exchange and oxygen spin polarization as mechanism for this rare-earth induced ferroelectricity.Comment: 8 pages, 5 figure

    Segundo informe del Observatorio de Costes y Financiación del Transporte Urbano Colectivo: encuesta a los gestores

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    A comienzos de 2012 se publicó el Primer Informe del Observatorio de Costes y Financiación del Transporte Urbano Colectivo (OTUC), creado con el apoyo y colaboración de la Asociación de Empresas del Transporte Urbano Colectivo (ATUC) que ha facilitado la adhesión de las principales empresas representantes del sector analizado, con el objetivo fundamental de estudiar las condiciones de explotación de las empresas de transporte urbano colectivo en superficie en España. Consolidado el proyecto iniciado por el Observatorio, en septiembre de 2013 se publica su Segundo Informe, en el que, como se realizó en el primero, y al objeto de conocer la visión de los gestores y la valoración que otorgan a los principales puntos críticos del negocio, se desarrolló una encuesta cuyos resultados se muestran en el presente trabajo.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tec

    Finite strain Landau theory of high pressure phase transformations

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    The properties of materials near structural phase transitions are often successfully described in the framework of Landau theory. While the focus is usually on phase transitions, which are induced by temperature changes approaching a critical temperature T-c, here we will discuss structural phase transformations driven by high hydrostatic pressure, as they are of major importance for understanding processes in the interior of the earth. Since at very high pressures the deformations of a material are generally very large, one needs to apply a fully nonlinear description taking physical as well as geometrical nonlinearities (finite strains) into account. In particular it is necessary to retune conventional Landau theory to describe such phase transitions. In Troster et al (2002 Phys. Rev. Lett. 88 55503) we constructed a Landau-type free energy based on an order parameter part, an order parameter-(finite) strain coupling and a nonlinear elastic term. This model provides an excellent and efficient framework for the systematic study of phase transformations for a wide range of materials up to ultrahigh pressures

    Landau Theory of Domain Wall Magnetoelectricity

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    We calculate the exact analytical solution to the domain wall properties in a multiferroic system with two order parameters that are coupled bi-quadratically. This is then adapted to the case of a magnetoelectric multiferroic material such as BiFeO3, with a view to examine critically whether the domain walls can account for the enhancement of magnetization reported for thin films fo this material, in view of the correlation between increasing magnetization and increasing volume fraction of domain walls as films become thinner. The present analysis can be generalized to describe a class of magnetoelectric devices based upon domain walls rather than bulk properties.Comment: 9 pages, 4 figure

    Effect of sodium hypochlorite on microleakage of composite restorations bonded with a polyalkenoic containing adhesive system

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    Abstract no. 905published_or_final_versio

    Microtensile bond strength of several adhesive systems to different dentin depths

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    Abstract no. 15published_or_final_versio
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