"Profitability and the Time-Varying Liquidity Premium in the Term Structure of Interest Rates"

There have been numerous empirical studies of the term structure. Broadly, the evidence may be said to be consistent with some influence from expectations plus the existence of a liquidity premium. Long rates or the spread between long and short rates have seemed to be systematically related to expectations of future rates, though the expectations embodied in long rates or the spread are biased upwards as the liquidity preference theory would predict. The degree of influence of expectations and the behavior of the liquidity premium, however, have remained matters of controversy. In several recent studies (e.g., Robert Shillert 1979; Shiller, John Campbell, and Kermit Schoenholtz, 1983; David Jones and Vance Roley, 1983; Mankiw and Summers, 1984; and Mankiw, 1986) the expectations theory has performed poorly, even allowing for the existence of a constant liquidity premium, in attempts to test the joint hypothesis of rational expectations and the expectations theory. Shiller, Campbell, and Schoenholtz and Mankiw and Summers, among others, have suggested renewing the search for the determinants of a time-varying liquidity premium as a possibility for explaining what is going on but have had little success themselves in finding such.

From where does the Red Tory speak?, Phillip Blond, theology and public discourse

This is the author's pdf version of an article published in Political Theology. The article can be found at www.politicaltheology.com/PT/This journal examines the role of theology in the public discourse of Philip Blond

A multimedia tutorial shell with qualitative assessment in biology

The project is developing methods to produce multimedia tutorials relatively quickly and cheaply, using a generic software shell suitable for any subject area. The shell is a version of one produced originally as part of the HEFC-funded TLTP initiative by the Biodiversity Consortium. Tutorials presented in the shell will provide the student with a structured learning experience that will allow their initial knowledge level or their knowledge acquisition and progress to be qualitatively and quantitatively assessed. Where areas of weakness are revealed by the assessment, students will be advised to study particular parts of the tutorial in order to improve their understanding

Physical properties of lava flows on the southwest flank of Tyrrhena Patera, Mars

Tyrrhena Patera (TP) (22 degrees S, 253.5 degrees W), a large, low-relief volcano located in the ancient southern highlands of Mars, is one of four highland paterae thought to be structurally associated with the Hellas basin. The highland paterae are Hesperian in age and among the oldest central vent volcanoes on Mars. The morphology and distribution of units in the eroded shield of TP are consistent with the emplacement of pyroclastic flows. A large flank unit extending from TP to the SW contains well-defined lava flow lobes and leveed channels. This flank unit is the first definitive evidence of effusive volcanic activity associated with the highland paterae and may include the best preserved lava flows observed in the Southern Hemisphere of Mars. Flank flow unit averages, channelized flow, flow thickness, and yield strength estimates are discussed. Analysis suggests the temporal evolution of Martian magmas

Changes in the Spatial Allocation of Cropland in the Ft. Cobb Watershed as a Result of Environmental Restrictions

Pollution runoff estimates from SWAT are used in a mathematical programming model to optimally model site-specific crop and conservation practices for pollution abatement in the Ft. Cobb watershed in Southwestern Oklahoma. Results indicate the tradeoffs between producer income, sediment and nutrient runoff and the spatial allocation of crops in the watershed.Environmental Economics and Policy,

Policing alcohol and illicit drug use among Aboriginal and Torres Strait Islander people in metropolitan environments

Executive summary: This report presents the results of Australian Institute of Criminology research on issues and challenges of policing alcohol and illicit drug use among Aboriginal and Torres Strait Islander people in metropolitan environments. This report is a companion to the 2006 National Drug Law Enforcement Research Fund project The policing implications of cannabis, amphetamine and other illicit drug use in Aboriginal and Torres Strait Islander communities. The main purpose of both pieces of research was to contribute to police service knowledge of substance use by Indigenous people and to provide a framework for good practice policing of the issues associated with alcohol and drug misuse. Report structure The first section of this report provides a summary of available data on Indigenous alcohol and other drug (AOD) use in metropolitan areas. The second section reports on the challenges that police and other stakeholders identified through survey results and focus group/interview consultations that relate to policing Indigenous substance use in metropolitan areas. The final section of the report presents a suggested framework for adapting the good practice framework developed in Delahunty and Putt’s research for general use within metropolitan areas

Immune- and nonimmune-compartment-specific interferon responses are critical determinants of herpes simplex virus-induced generalized infections and acute liver failure

The interferon (IFN) response to viral pathogens is critical for host survival. In humans and mouse models, defects in IFN responses can result in lethal herpes simplex virus 1 (HSV-1) infections, usually from encephalitis. Although rare, HSV-1 can also cause fulminant hepatic failure, which is often fatal. Although herpes simplex encephalitis has been extensively studied, HSV-1 generalized infections and subsequent acute liver failure are less well understood. We previously demonstrated that IFN-αβγR-/- mice are exquisitely susceptible to liver infection following corneal infection with HSV-1. In this study, we used bone marrow chimeras of IFN-αβγR-/- (AG129) and wild-type (WT; 129SvEv) mice to probe the underlying IFN-dependent mechanisms that control HSV-1 pathogenesis. After infection, WT mice with either IFN-αβγR-/- or WT marrow exhibited comparable survival, while IFN-αβγR-/- mice with WT marrow had a significant survival advantage over their counterparts with IFN-αβγR-/- marrow. Furthermore, using bioluminescent imaging to maximize data acquisition, we showed that the transfer of IFN-competent hematopoietic cells controlled HSV-1 replication and damage in the livers of IFN-αβγR-/- mice. Consistent with this, the inability of IFN-αβγR-/- immune cells to control liver infection in IFN-αβγR-/- mice manifested as profoundly elevated aspartate transaminase (AST) and alanine transaminase (ALT) levels, indicative of severe liver damage. In contrast, IFN-αβγR-/-mice receiving WT marrow exhibited only modest elevations of AST and ALT levels. These studies indicate that IFN responsiveness of the immune system is a major determinant of viral tropism and damage during visceral HSV infections