The valuation of riparian fisheries in Southern and Eastern Africa

This paper reviews the published and gray literature concerning economic valuations of river fisheries in eastern and southern Africa, extracting the best available information on their direct economic values and on the impacts of changes in water management on this value. It then assesses the methods used and makes recommendations regarding approaches to be used in future. The review concentrates on rivers with their associated floodplains and major deltas. The values and issues associated with estuaries and lakes are not considered

Physical activity promotion in care homes

Purpose: The purpose of this paper is to report on the implementation of a physical activity (PA) scheme – Let’s Motivate (LM) – within private care homes (CHs) in Dumfries and Galloway (D&G), Scotland; aiming to provide an insight into the different factors which might contribute to its success and further sustainability. Design/methodology/approach: A qualitative study is described in which one-to-one semi-structured interviews were carried out with eight key staff involved in implementing the project within two purposively sampled CHs; in order to explore their views and experiences of implementation. Findings: The paper provides an insight into the different factors which stand to both promote and impede the successful implementation of LM, within the two CHs involved. Originality/value: This paper explores a new and innovative PA initiative in CHs in D&G, Scotland. Studies exploring the factors which can both promote and impede implementation are important as they can help to usefully inform the implementation and sustainability of initiatives

Preliminary economic assessment of water resources of the Pangani River Basin, Tanzania

River basin managementWater useWater allocationEconomic evaluationDomestic waterIrrigation waterLivestockWater power

Promoting integration within the public health domain of physical activity promotion: insights from a UK case study

Purpose: The purpose of this paper is to report and critically reflect on the methodological processes involved in a formal attempt to promote health and social integration in the rarely reported public health domain of physical activity promotion. Design/methodology/approach: A quality improvement (QI) methodology was deployed, comprising three elements: a diagnostic tool that assessed strategic and practice positions; a half-day workshop that brought senior leaders together for to reflect this evidence; and a structured process that sought to generate proposals for future integrated action. A mixed-method evaluative approach was used, capturing insights of the integration processes via quantitative and qualitative data collection pre-event, in-event, immediate post-event and at six-month follow-up. Findings: Insights suggested that despite some critical concerns, this QI process can be considered as robust, offering pointers to elements required to successfully promote integration in this domain, including the significance of leadership, the preparatory contribution of a diagnostic tool and position paper, the opportunities for active exchange and planning within a workshop situation and the initiation of a process of integrated work via tangible “pledges”. Originality/value: The paper offers originality in two respects. Generally, it describes and reflects on the relationship between theoretical and empirical dimensions of a model of integration promotion. Specifically, in offering an account of integrative public health work across health service, local authority and third sector partners, it addressed an area that has received relatively limited prior attention

XANTUS: rationale and design of a noninterventional study of rivaroxaban for the prevention of stroke in patients with atrial fibrillation.

Atrial fibrillation (AF) is associated with a fivefold increase in the risk of stroke. The Phase III ROCKET AF (Rivaroxaban Once-Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation) trial showed that rivaroxaban, an oral, direct Factor Xa inhibitor, was noninferior to warfarin for the reduction of stroke or systemic embolism in patients with AF. Compared with warfarin, rivaroxaban significantly reduced rates of intracranial and fatal hemorrhages, although not rates of bleeding overall. XANTUS (Xarelto(®) for Prevention of Stroke in Patients with Atrial Fibrillation) is a prospective, international, observational, postauthorization, noninterventional study designed to collect safety and efficacy data on the use of rivaroxaban for stroke prevention in AF in routine clinical practice. The key goal is to determine whether the safety profile of rivaroxaban established in ROCKET AF is also observed in routine clinical practice. XANTUS is designed as a single-arm cohort study to minimize selection bias, and will enroll approximately 6,000 patients (mostly from Europe) with nonvalvular AF prescribed rivaroxaban, irrespective of their level of stroke risk. Overall duration of follow-up will be 1 year; the first patient was enrolled in June 2012. Similar studies (XANTUS-EL [Xarelto(®) for Prevention of Stroke in Patients with Nonvalvular Atrial Fibrillation, Eastern Europe, Middle East, Africa and Latin America] and XANAP [Xarelto(®) for Prevention of Stroke in Patients with Atrial Fibrillation in Asia-Pacific]) are ongoing in Latin America and Asia-Pacific. Data from these studies will supplement those from ROCKET AF and provide practical information concerning the use of rivaroxaban for stroke prevention in AF

Role of new anticoagulants for the prevention of venous thromboembolism after major orthopaedic surgery and in hospitalised acutely ill medical patients.

SummaryAnticoagulation therapy for the prevention of venous thromboembolic events is indicated in patients after major orthopaedic surgery and in hospitalised acutely ill medical patients, who have a high or moderate risk of venous thromboembolism (VTE), respectively. Clinical trials have clearly demonstrated that short-term anticoagulation reduces the risk of VTE in these patient groups and that longer-term anticoagulation is beneficial for some indications. Evidence-based guidelines for throm-boprophylaxis have been developed based on these studies. However, despite these guidelines, thromboprophylaxis is still underused, or used suboptimally, in many patients. This is, in part, because of the limitations of traditional anticoagulants such as unfractionated heparin, lowmolecular-weight heparin, synthetic pentasaccharides, and vitamin K antagonists. Newer oral anticoagulants, such as rivaroxaban, apixaban, and dabigatran etexilate, have certain advantages over traditional agents. They can be administered orally at a fixed dose without routine coagulation monitoring and have minimal food and drug interactions. These characteristics may result in better adherence to guidelines and improved patient outcomes. This review provides an overview of phase III clinical trial data for these newer anticoagulants in major orthopaedic surgery and in hospitalised acutely ill medical patients, and discusses their potential for extended use in the post-hospital discharge setting. All three newer oral anticoagulants are approved in many countries for the prevention of VTE after hip replacement or knee replacement surgery in adult patients, and it is likely that these drugs will contribute considerably towards reducing the substantial healthcare burden associated with VTE.</jats:p

Preliminary economic assessment of water resources of the Pangani River Basin, Tanzania: economic values and incentives

River basinsEconomic analysisDomestic waterIrrigated farmingLivestockPolicyWater supplyFinancing

Impact of Modifiable Bleeding Risk Factors on Major Bleeding in Patients With Atrial Fibrillation Anticoagulated With Rivaroxaban.

Background Reducing major bleeding events is a challenge when managing anticoagulation in patients with atrial fibrillation. This study evaluated the impact of modifiable and nonmodifiable bleeding risk factors in patients with atrial fibrillation receiving rivaroxaban and estimated the impact of risk factor modification on major bleeding events. Methods and Results Modifiable and nonmodifiable risk factors associated with major bleeding events were identified from the XANTUS (Xarelto for Prevention of Stroke in Patients With Atrial Fibrillation) prospective registry data set (6784 rivaroxaban-treated patients). Parameters showing univariate association with bleeding were used to construct a multivariable model identifying independent risk factors. Modeling was used to estimate attributed weights to risk factors. Heavy alcohol use (hazard ratio [HR]=2.37; 95% CI 1.24-4.53); uncontrolled hypertension (HR after parameter-wise shrinkage=1.79; 95% CI 1.05-3.05); and concomitant treatment with antiplatelets, nonsteroidal anti-inflammatory drugs, or paracetamol (HR=1.80; 95% CI 1.24-2.61) were identified as modifiable, independent bleeding risk factors. Increasing age (HR=1.25 [per 5-year increment]; 95% CI 1.12-1.38); heart failure (HR=1.97; 95% CI 1.36-2.86); and vascular disease (HR=1.91; 95% CI 1.32-2.77) were identified as nonmodifiable bleeding risk factors. Overall, 128 (1.9%) patients experienced major bleeding events; of these, 11% had no identified bleeding risk factors, 50% had nonmodifiable bleeding risk factors only, and 39% had modifiable bleeding risk factors (with or without nonmodifiable risk factors). The presence of 1 modifiable bleeding risk factor doubled the risk of major bleeding. Conclusions Elimination of modifiable bleeding risk factors is a potentially effective strategy to reduce bleeding risk in atrial fibrillation patients receiving rivaroxaban. Clinical Trial Registration URL: http://www.clinicaltrials.gov. Unique identifier: NCT01606995

Technical guidelines for economic valuation of inland small-scale fisheries in developing countries

These ôTechnical Guidelines for Economic Valuation of Inland Small-scale Fisheries in Developing Countriesö are one of the outputs of the project on ôFood security and poverty alleviation through improved valuation and governance of river fisheries in Africaö. The guidelines draw upon research results and experience gained during the course of the project. The project was coordinated and implemented by the WorldFish Center and was carried out in cooperation with the National Agricultural Research Institutes (NARs) from the participating countries: the Nigeria Institute for Freshwater Fisheries Research, the Departments of Fishery of Niger, Malawi and Zambia, and the Cameroonian MinistΦre de lÆElevage, des PΩches et de lÆIndustrie Animale; and three advanced research institutes (ARIs): the Leibniz University of Hannover in Germany, the Institute for Sustainable Development and Aquatic Resources in UK, and the University of Cape Town in South Africa.Rural development, Sustainable development, Livelihoods, Economic analysis, Research, Artisanal fishing

NASA 2014 The Hyperspectral Infrared Imager (HyspIRI) - Science Impact of Deploying Instruments on Separate Platforms

The Hyperspectral Infrared Imager (HyspIRI) mission was recommended for implementation by the 2007 report from the U.S. National Research Council Earth Science and Applications from Space: National Imperatives for the Next Decade and Beyond, also known as the Earth Science Decadal Survey. The HyspIRI mission is science driven and will address a set of science questions identified by the Decadal Survey and broader science community. The mission includes a visible shortwave infrared (VSWIR) imaging spectrometer, a multispectral thermal infrared (TIR) imager and an intelligent payload module (IPM). The IPM enables on-board processing and direct broadcast for those applications with short latency requirements. The science questions are organized as VSWIR-only, TIR-only and Combined science questions, the latter requiring data from both instruments. In order to prepare for the mission NASA is undertaking pre-phase A studies to determine the optimum mission implementation, in particular, cost and risk reduction activities. Each year the HyspIRI project is provided with feedback from NASA Headquarters on the pre-phase A activities in the form of a guidance letter which outlines the work that should be undertaken the subsequent year. The 2013 guidance letter included a recommendation to undertake a study to determine the science impact of deploying the instruments from separate spacecraft in sun synchronous orbits with various time separations and deploying both instruments on the International Space Station (ISS). This report summarizes the results from that study. The approach taken was to evaluate the impact on the combined science questions of time separations between the VSWIR and TIR data of <3 minutes, <1 week and a few months as well as deploying both instruments on the ISS. Note the impact was only evaluated for the combined science questions which require data from both instruments (VSWIR and TIR). The study concluded the impact of a separation of <3 minutes was minimal, e.g. if the instruments were on separate platforms that followed each other in a train. The impact of a separation of <1 week was strongly dependent on the question that was being addressed with no impact for some questions and a severe impact for others. The impact of a time separation of several months was severe and in many cases it was no longer possible to answer the sub-question. The impact of deploying the instruments on the ISS which is in a precessive (non-sun synchronous) orbit was also very question dependent, in some cases it was possible to go beyond the original question, e.g. to examine the impact of the diurnal cycle, whereas in other cases the question could not be addressed for example if the question required observations from the polar regions. As part of the study, the participants were asked to estimate, as a percentage, how completely a given sub-question could be answered with 100% indicating the question could be completely answered. These estimations should be treated with caution but nonetheless can be useful in assessing the impact. Averaging the estimates for each of the combined questions the results indicate that 97% of the questions could be answered with a separation of < 3 minutes. With a separation of < 1 week, 67% of the questions could be answered and with a separation of several months only 21% of the questions could be answered