24 research outputs found
Phenolic content and antioxidant activity of selected wild mushrooms from Tricholomataceae family, collected in Macedonia
Phenolic profile and biological activity of Hypericum perforatum L.: Can roots be considered as a new source of natural compounds?
Associations of phenolic contents with antioxidant capacities of selected Macedonian wild fungi
Identification and quantification of phenolic compounds in Hypericum perforatum L. transgenic shoots
The impact of media composition on production of flavonoids in agitated shoot cultures of the three Hypericum perforatum L. cultivars ‘Elixir,’ ‘Helos,’ and ‘Topas’
Secondary metabolite production in Hypericum perforatum L. cell suspensions upon elicitation with fungal mycelia from Aspergillus flavus
We investigated the production of phenylpropanoids (phenolic compounds, flavanols, flavonols and anthocyanins) and naphtodianthrones (hypericins) in elicited Hypericum perforatum L. cell suspensions. To determine whether secondary metabolite production could be enhanced, Hypericum cell suspensions were exposed to mycelia extract from the fungus Aspergillus flavus. Elicited Hypericum cell suspension cultures displayed reduced growth and viability and a modification of secondary metabolites production. Anthocyanins were only stimulated in fungal-elicited cell suspensions. Secondary metabolite production in elicited Hypericum cells revealed an antagonism between the flavonoid/naphtodianthrone and anthocyanin pathways. The data suggest a modification of the channeling of the phenylpropanoid compounds. Together, these results represent useful data for monitoring the channeling in different secondary metabolite pathways during the scaled-up production of naphtodianthrones for medicinal uses
Secondary metabolite production in Hypericum perforatum L. cell suspensions upon elicitation with fungal mycelia from Aspergillus flavus
We investigated the production of phenylpropanoids (phenolic compounds,
flavanols, flavonols and anthocyanins) and naphtodianthrones (hypericins) in
elicited Hypericum perforatum L. cell suspensions. To determine whether
secondary metabolite production could be enhanced, Hypericum cell suspensions
were exposed to mycelia extract from the fungus Aspergillus flavus. Elicited
Hypericum cell suspension cultures displayed reduced growth and viability and
a modification of secondary metabolites production. Anthocyanins were only
stimulated in fungal-elicited cell suspensions. Secondary metabolite
production in elicited Hypericum cells revealed an antagonism between the
flavonoid/naphtodianthrone and anthocyanin pathways. The data suggest a
modification of the channeling of the phenylpropanoid compounds. Together,
these results represent useful data for monitoring the channeling in
different secondary metabolite pathways during the scaled-up production of
naphtodianthrones for medicinal uses.</jats:p
