1,283 research outputs found
Tecnologias apropriadas para o desenvolvimento sustentado da bovinocultura de corte no Pantanal.
O sistema tradicional de producao; A cadeia produtiva da pecuaria de corte no Pantanal; Distribuicao e evolucao dos principais aspectos agropecuarios nas sub-regioes do Pantanal; Introducao de tecnologias na criacao de bovinos de corte no Pantanal.bitstream/item/37741/1/DOC24.pd
Efficient total energy calculations from self-energy models
We propose a new method for calculating total energies of systems of interacting electrons, which requires little more computational resources than standard density-functional theories. The total energy is calculated within the framework of many-body perturbation theory by using an efficient model of the self-energy, that nevertheless retains the main features of the exact operator. The method shows promising performance when tested against quantum Monte Carlo results for the linear response of the homogeneous electron gas and structural properties of bulk silicon
BAFF- and TACI-Dependent Processing of BAFFR by ADAM Proteases Regulates the Survival of B Cells.
B cell activating factor (BAFF) provides B cells with essential survival signals. It binds to three receptors: BAFFR, TACI, and BCMA that are differentially expressed by B cell subsets. BAFFR is early expressed in circulating B cells and provides key signals for further maturation. Here, we report that highly regulated BAFFR processing events modulate BAFF responses. BAFFR processing is triggered by BAFF binding in B cells co-expressing TACI and it is executed by the metalloproteases ADAM10 and ADAM17. The degree of BAFF oligomerization, the expression of ADAM proteins in different B cell subsets, and the activation status of the cell determine the proteases involved in BAFFR processing. Inhibition of ADAM10 augments BAFF-dependent survival of primary human B cells, whereas inhibition of ADAM17 increases BAFFR expression levels on germinal center B cells. Therefore, BAFF-induced processing of BAFFR regulates BAFF-mediated B cell responses in a TACI-dependent manner
Стадии экономической оценки месторождения
The cAMP response element modulator (CREM)α is a widely expressed transcriptional repressor that is important for the termination of the T cell immune response and contributes to the abnormal T cell function in patients with systemic lupus erythematosus. We present evidence that APCs of Crem(−/−) mice express increased amounts of the costimulatory molecule CD86 and induce enhanced Ag-dependent and Ag-independent T cell proliferation. Similarly, human APCs in which CREMα was selectively suppressed expressed more CD86 on the surface membrane. CREMα was found to bind to the CD86 promoter and suppressed its activity. Transfer of APCs from Crem(−/−) mice into naive mice facilitated a significantly stronger contact dermatitis response compared with mice into which APCs from Crem(+/+) mice had been transferred. We conclude that CREMα is an important negative regulator of costimulation and APC-dependent T cell function both in vitro and in vivo
Arbitrary Choice of Basic Variables in Density Functional Theory. II. Illustrative Applications
Our recent theory (Ref. 1) enables us to choose arbitrary quantities as the
basic variables of the density functional theory. In this paper we apply it to
several cases. In the case where the occupation matrix of localized orbitals is
chosen as a basic variable, we can obtain the single-particle equation which is
equivalent to that of the LDA+U method. The theory also leads to the
Hartree-Fock-Kohn-Sham equation by letting the exchange energy be a basic
variable. Furthermore, if the quantity associated with the density of states
near the Fermi level is chosen as a basic variable, the resulting
single-particle equation includes the additional potential which could mainly
modify the energy-band structures near the Fermi level.Comment: 27 page
Observation of the decay
We report the first observation of decay. These results
are obtained from a data sample that contains 449 million pairs
accumulated at the resonance with the Belle detector at the KEKB
asymmetric-energy collider. We observe a signal with a significance
of 8.1 and obtain a branching fraction of (9.5 1.7 (stat)
0.8 (syst)).Comment: 5 pages, 2 figures, submit to PRL (8 pages, 2 figures, ICHEP'06
Conference Paper
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