517 research outputs found

    Henri Temianka Correspondence; (unrath)

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    This collection contains material pertaining to the life, career, and activities of Henri Temianka, violin virtuoso, conductor, music teacher, and author. Materials include correspondence, concert programs and flyers, music scores, photographs, and books.https://digitalcommons.chapman.edu/temianka_correspondence/4219/thumbnail.jp

    Becoming Magic: Acquiring the Artist Identity

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    This research mines the internal reflective process of an artist/researcher/teacher who witnesses her own becoming, seeing herself, in multiples and weaves a multimodal narrative while contemplating, revealing, and living multiple identities through visual inquiry. The purpose of this research, in its broadest sense, is to better understand the nature of artistic identity and how it is acquired in personal, social and educational contexts. As an artist/researcher/teacher, I seek to know how we might create more fertile conditions and facilitate appropriate rites of passage for transitioning individuals from student/teacher/aspirant to self-actualized artist

    Stability of white matter changes related to Huntington's disease in the presence of imaging noise: a DTI study.

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    Movement artifacts and other sources of noise are a matter of concern particularly in the neuroimaging research of movement disorders such as Huntington's disease (HD). Using diffusion weighted imaging (DWI) and fractional anisotropy (FA) as a compound marker of white matter integrity, we investigated the effect of movement on HD specific changes in magnetic resonance imaging (MRI) data and how post hoc compensation for it affects the MRI results. To this end, we studied by 3T MRI: 18 early affected, 22 premanifest gene-positive subjects, 23 healthy controls (50 slices of 2.3 mm thickness per volume, 64 diffusion-weighted directions (b = 1000 s/mm2), 8 minimal diffusion-weighting (b = 100 s/mm2)); and by 1.5 T imaging: 29 premanifest HD, 30 controls (40 axial slices of 2.3 mm thickness per volume, 61 diffusion-weighted directions (b = 1000 s/mm2), minimal diffusion-weighting (b = 100 s/mm2)). An outlier based method was developed to identify movement and other sources of noise by comparing the index DWI direction against a weighted average computed from all other directions of the same subject. No significant differences were observed when separately comparing each group of patients with and without removal of DWI volumes that contained artifacts. In line with previous DWI-based studies, decreased FA in the corpus callosum and increased FA around the basal ganglia were observed when premanifest mutation carriers and early affected patients were compared with healthy controls. These findings demonstrate the robustness of the FA value in the presence of movement and thus encourage multi-center imaging studies in HD

    Dynamic exploration of helicopter reconnaissance through agent-based modeling

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    This thesis uses Multi-Agent System modeling to develop a simulation of tactical helicopter performance while conducting armed reconnaissance. It focuses on creating a model to support planning for the Test and Evaluation phas of the Comanche helicopter acquisition cycle. The model serves as an initial simulation laboratory for scenario planning, requirements forecasting, and platform comparison analyses. The model implements adaptive tactical movement with agent sensory and weaponry system characteristics. Agents are able to determine their movement direction and paths based on their perceived environment, attributes, and movement personalities. The model incorporates a three-dimensional aspect to properly simulate aerial reconnaissance. An integrated Graphical User Interface enables the user to create environments, instantiate agent propensities and attributes, set simulation parameters, and analyze statistical output. The resulting model demonstrates the ability to represent helicopter reconnaissance behavior. It captures simulation summary statistics that illustrate enemy performance, helicopter performance, and logistical requirements. The model establishes an initial simulation tool to further explore Comanche operational requirements and planning foi its Test and Evaluation phase. 14. SUBJECT TERMS 15. NUMBER OF Multi-Agent System, Agent- Based Modeling, Helicopter Reconnaissance, Comanche, Adaptive PAGES 140 Behavior, Modeling and Simulationhttp://www.archive.org/details/dynamicexplorati00unraU.S. Army (USA) autho

    Diffusion-weighted magnetic resonance imaging detection of basal forebrain cholinergic degeneration in a mouse model

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    Loss of basal forebrain cholinergic neurons is an early and key feature of Alzheimer's disease, and magnetic resonance imaging (MRI) volumetric measurement of the basal forebrain has recently gained attention as a potential diagnostic tool for this condition. The aim of this study was to determine whether loss of basal forebrain cholinergic neurons underpins changes which can be detected through diffusion MRI using diffusion tensor imaging (DTI) and probabilistic tractography in a mouse model. To cause selective basal forebrain cholinergic degeneration, the toxin saporin conjugated to a p75 neurotrophin receptor antibody (mu-p75-SAP) was used. This resulted in similar to 25% loss of the basal forebrain cholinergic neurons and significant loss of terminal cholinergic projections in the hippocampus, as determined by histology. To test whether lesion of cholinergic neurons caused basal forebrain, hippocampal, or whole brain atrophy, we performed manual segmentation analysis, which revealed no significant atrophy in lesioned animals compared to controls (Rb-IgG-SAP). However, analysis by DTI of the basal forebrain area revealed a significant increase in fractional anisotropy (FA; + 7.7%), mean diffusivity (MD; + 6.1%), axial diffusivity (AD; + 8.5%) and radial diffusivity (RD; +4.0%) in lesioned mice compared to control animals. These parameters strongly inversely correlated with the number of choline acetyl transferase-positive neurons, with FA showing the greatest association (r(2) = 0.72), followed by MD (r(2) = 0.64), AD (r(2) = 0.64) and RD (r(2) = 0.61). Moreover, probabilistic tractography analysis of the septo-hippocampal tracts originating from the basal forebrain revealed an increase in streamline MD (+5.1%) and RD (+4.3%) in lesioned mice. This study illustrates that moderate loss of basal forebrain cholinergic neurons (representing only a minor proportion of all septo-hippocampal axons) can be detected by measuring either DTI parameters of the basal forebrain nuclei or tractography parameters of the basal forebrain tracts. These findings provide increased support for using DTI and probabilistic tractography as non-invasive tools for diagnosing and/or monitoring the progression of conditions affecting the integrity of the basal forebrain cholinergic system in humans, including Alzheimer's disease. Crown Copyright (C) 2012 Published by Elsevier Inc. All rights reserved

    Cambios en las creencias, emociones y comportamientos de una persona con trastorno por atracón que asiste a psicoterapia

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    En la actualidad, el trastorno por atracón se presenta cada vez con mayor frecuencia. Sin embargo, es poco frecuente que quienes lo padecen busquen ayuda profesional principalmente psicológica, por algunas características del trastorno como lo son la vergüenza de reconocer sus comportamientos alimentarios y la escasa consciencia del padecimiento. Además, la reciente independencia del trastorno por atracón de la bulimia vuelve relativamente novedoso a su tratamiento específico a pesar de mantener ciertas características del tratamiento de la Bulimia. El presente trabajo tiene como objetivo general describir los cambios en las creencias, emociones y comportamientos asociados al trastorno por atracón en una persona que asiste a psicoterapia. Se realizó desde una perspectiva de investigación cualitativa de alcance descriptivo y por medio de un estudio de caso único y de un análisis temático, se analizaron fragmentos de un total de ocho sesiones del inicio, intermedio y final del proceso psicoterapéutico, por medio de los cuales se evaluaron los cambios en las creencias, emociones y comportamientos. Los resultados obtenidos muestran distintos cambios significativos en las tres categorías. La categoría de creencias fue la primera en presentar cambios y a partir de esto, la categoría de emociones y posteriormente la de comportamientos presentaron transformaciones que aportaron a una mejora en la calidad de vida de la consultante. Como conclusión, se puede observar el impacto positivo que un proceso de psicoterapia tiene en el tratamiento del trastorno por atracón. Por medio de éste, la consultante fue presentando cambios en el reconocimiento e identificación de sus emociones y creencias al adquirir mayor conciencia de su problemática, lo cual la llevó a modificar sus comportamientos al comenzar a implementar acciones que le aportaban a su bienestar y principalmente, a la disminución de sus episodios de atracón.ITESO, A. C

    Illokutive Strukturen und Dialoganalyse

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    The aim of this work is to describe dialog structures: dialogue structures that express different attitudes of interlocutors to the conversation and the partner. In addition, however, my hope is to be able to point out a possible way through the description of a dialogical attitude and the corresponding discussion structures, using specific "techniques" so structured and structured conversations that they lead to real understanding and thus to an improvement of the culture of dialogue

    Diffusion tensor imaging and tractwise fractional anisotropy statistics: quantitative analysis in white matter pathology

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    <p>Abstract</p> <p>Background</p> <p>Information on anatomical connectivity in the brain by measurements of the diffusion of water in white matter tracts lead to quantification of local tract directionality and integrity.</p> <p>Methods</p> <p>The combination of connectivity mapping (fibre tracking, FT) with quantitative diffusion fractional anisotropy (FA) mapping resulted in the approach of results based on group-averaged data, named tractwise FA statistics (TFAS). The task of this study was to apply these methods to group-averaged data from different subjects to quantify differences between normal subjects and subjects with defined alterations of the corpus callosum (CC).</p> <p>Results</p> <p>TFAS exhibited a significant FA reduction especially in the CC, in agreement with region of interest (ROI)-based analyses.</p> <p>Conclusion</p> <p>In summary, the applicability of the TFAS approach to diffusion tensor imaging studies of normal and pathologically altered brains was demonstrated.</p
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