Emotions and scope effects in the monetary valuation of health

JEL classifications: H41 H51 I11 I18 I31This study presents evidence on the role of emotions in the monetary evaluation of health technologies, namely, drug-eluting stents (DES) in our case. It is shown that subjects who are very afraid of having to undergo an angioplasty are: (a) less sensitive to the size of the risk reduction provided by DES and (b) willing to pay more. The lack of scope sensitivity questions the normative validity of the responses of highly emotional subjects. We provide evidence of this effect using what we call the cognitive-emotional random utility model and the responses of a face-to-face, computer-assisted personal interview survey conducted in a representative sample of the Spanish general population (n = 1663).3253150,9922,169Q1Q1SSC

The AMBRE Project: Stellar Parameterisation of the ESO:UVES archived spectra

The AMBRE Project is a collaboration between the European Southern Observatory (ESO) and the Observatoire de la Cote d'Azur (OCA) that has been established in order to carry out the determination of stellar atmospheric parameters for the archived spectra of four ESO spectrographs. The analysis of the UVES archived spectra for their stellar parameters has been completed in the third phase of the AMBRE Project. From the complete ESO:UVES archive dataset that was received covering the period 2000 to 2010, 51921 spectra for the six standard setups were analysed. The AMBRE analysis pipeline uses the stellar parameterisation algorithm MATISSE to obtain the stellar atmospheric parameters. The synthetic grid is currently constrained to FGKM stars only. Stellar atmospheric parameters are reported for 12,403 of the 51,921 UVES archived spectra analysed in AMBRE:UVES. This equates to ~23.9% of the sample and ~3,708 stars. Effective temperature, surface gravity, metallicity and alpha element to iron ratio abundances are provided for 10,212 spectra (~19.7%), while at least effective temperature is provided for the remaining 2,191 spectra. Radial velocities are reported for 36,881 (~71.0%) of the analysed archive spectra. Typical external errors of sigmaTeff~110dex, sigmalogg~0.18dex, sigma[M/H]~0.13dex, and sigma[alpha/Fe]~0.05dex with some reported variation between giants and dwarfs and between setups are reported. UVES is used to observe an extensive collection of stellar and non-stellar objects all of which have been included in the archived dataset provided to OCA by ESO. The AMBRE analysis extracts those objects which lie within the FGKM parameter space of the AMBRE slow rotating synthetic spectra grid. Thus by homogeneous blind analysis AMBRE has successfully extracted and parameterised the targeted FGK stars (23.9% of the analysed sample) from within the ESO:UVES archive.Comment: 19 pages, 16 figures, 11 table

Postoperative pain and morphine consumption after ultrasound-guided femoral and sciatic combined nerve block versus neurostimulation for femoral and sciatic combined nerve block or neurostimulation for femoral nerve block in primary elective total knee arthroplasty.

Abstract Congreso XXXVII National Meeting of the Spanish Society of Pharmacology with guest society: The British Pharmacological SocietyBackground and Aims: Total knee arthroplasty injuries are extremely painful and merit prompt attention to adequate postoperative analgesia. We aim to compare femoral and sciatic ultrasound-guided combined nerve block vs. neurostimulation for femoral and sciatic combined nerve block or for femoral nerve block in postoperative pain in primary elective total knee prosthesis. Summary of work and outcomes: A three arms, prospective longitudinal study of patients having primary elective unilateral knee prosthesis and randomly assigned to catheter insertion guided by ultrasound or neurostimulation was done: 1) Ultrasound-guided femoral and sciatic combined nerve block (USFSCN) (N=15); 2) Neurostimulation for femoral and sciatic combined nerve block (NSFSCN) (N=17); 3) Neurostimulation for femoral nerve block (NSFN) (N=11). Total analgesia (morphine) consumption after 48 hours was the primary endpoint. The postoperative pain intensity (visual analogue pain scale (VAS)) at post-anaesthetic recovery unit (PARU), 6, 24, 48 h, and during movement and postoperative complications were secondary outcomes. Results and discussion: 43 patients (68.3±8 years old, 77% female) subjected to elective unilateral knee prosthesis were enrolled. There were no differences in the demographic, anaesthetic and surgical variables between groups. Pain intensity was lower in the USFSCN group compared with NSFSCN and NSFN during the first 48 h post-surgery (% of intense pain at PARU/6h/24h/48h): USFSCN 0.8/1.4/3.2/1.6; NSFSCN 5.6/8.3/7.5/3; NSFN 7.2/5.3/6.4/5.4. The average consumption of morphine within 48 h after surgery was similar in the groups USFSCN and NSFSCN (3 mg vs. 3.11 mg), and significantly lower than NSFN (4.19 mg) (p<0.05). And the number of complications was significantly lower in the USFSCN group compared with NSFSCN and NSFN during the first 48 h of postoperative. Conclusion: Ultrasound-guided femoral and sciatic combined nerve block presented better analgesia and was more safety than neurostimulation for femoral and sciatic combined nerve block or for femoral nerve block in primary elective total knee arthroplasty.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech