Topological twisted sigma model with H-flux revisited

In this paper we revisit the topological twisted sigma model with H-flux. We explicitly expand and then twist the worldsheet Lagrangian for bi-Hermitian geometry. we show that the resulting action consists of a BRST exact term and pullback terms, which only depend on one of the two generalized complex structures and the B-field. We then discuss the topological feature of the model.Comment: 16 pages. Appendix adde

Modern Model of Competences of Personal Agents as Increase Factor of Clients’ Subjective Well-being

The model of competences of personal agents is developed in the article. The model allows raising the level of subjective well-being of clients and promotes the growth of main indicators characterizing productivity of personal selling. The author designates a new group of stakeholders with which the company has to develop relationship for realization of a social orientation. Relationship marketing is defined taking into account the priority of its broad treatments and orientation on developing relationships with various groups of people. The concept ‘personal agent’ is entered into the theory of marketing. This concept reflects the activity of the seller in modern conditions more precisely. The definition of personal selling is given. Novelty of the author's formulation of this definition is that the personal agents have to own skillfully technologies of sales for achieving their purpose. It is proved that the main objective of personal selling in the context of relationship marketing is not sale of goods, but development of relationship between clients and personal agents (company). The author proves the importance of application of psychological theories and offers the method of creation of a psychological portrait of clients on the basis of classification of standard psychological characteristics. The behavioural indicators characterizing demonstration of all main competences of personal agents are revealed and presented

Two-Dimensional Dilaton-Gravity Coupled to Massless Spinors

We apply a global and geometrically well-defined formalism for spinor-dilaton-gravity to two-dimensional manifolds. We discuss the general formalism and focus attention on some particular choices of the dilatonic potential. For constant dilatonic potential the model turns out to be completely solvable and the general solution is found. For linear and exponential dilatonic potentials we present the class of exact solutions with a Killing vector.Comment: 21 pages, LaTeX, minor changes in text and format, final version to appear in Classical and Quantum Gravit

Chiral anomaly for local boundary conditions

It is known that in the zeta function regularization and in the Fujikawa method chiral anomaly is defined through a coefficient in the heat kernel expansion for the Dirac operator. In this paper we apply the heat kernel methods to calculate boundary contributions to the chiral anomaly for local (bag) boundary conditions. As a by-product some new results on the heat trace asymptotics are also obtained.Comment: 20 p., late

Fundamental Strings in Open String Theory at the Tachyonic Vacuum

We show that the world-volume theory on a D-p-brane at the tachyonic vacuum has solitonic string solutions whose dynamics is governed by the Nambu-Goto action of a string moving in (25+1) dimensional space-time. This provides strong evidence for the conjecture that at this vacuum the full (25+1) dimensional Poincare invariance is restored. We also use this result to argue that the open string field theory at the tachyonic vacuum must contain closed string excitations.Comment: LaTeX file, 16 pages, references and clarification adde

Conifolds and Geometric Transitions

Conifold geometries have recieved a lot of attention in string theory and string-inspired cosmology recently, in particular the Klebanov-Strassler background that is known as the "warped throat". It is our intention in this article to give a pedagogical explanation for the singularity resolution in this geometry and emphasise its connection to geometric transitions. The first part focuses on the gauge theory dual to the Klebanov-Strassler background, which we also explain from a T-dual intersecting branes scenario. We then make the connection to the Gopakumar-Vafa conjecture for open/closed string duality and summarise a series of papers verifying this model on the supergravity level. An appendix provides extensive background material about conifold geometries. We pay special attention to their complex structures and re-evaluate the supersymmetry conditions on the background flux in constructions with fractional D3-branes on the singular (Klebanov-Tseytlin) and resolved (Pando Zayas-Tseytlin) conifolds. We agree with earlier results that only the singular solution allows a supersymmetric flux, but point out the importance of using the correct complex structure to reach this conclusion.Comment: 37 pages, v3: accepted for publication in Reviews of Modern Physic

Development and validation of two self-reported tools for insulin resistance and hypertension risk assessment in a European cohort : the Feel4Diabetes-study

Early identification of type 2 diabetes mellitus (T2DM) and hypertension (HTN) risk may improve prevention and promote public health. Implementation of self-reported scores for risk assessment provides an alternative cost-effective tool. The study aimed to develop and validate two easy-to-apply screening tools identifying high-risk individuals for insulin resistance (IR) and HTN in a European cohort. Sociodemographic, lifestyle, anthropometric and clinical data obtained from 1581 and 1350 adults (baseline data from the Feel4Diabetes-study) were used for the European IR and the European HTN risk assessment index respectively. Body mass index, waist circumference, sex, age, breakfast consumption, alcohol, legumes and sugary drinks intake, physical activity and sedentary behavior were significantly correlated with Homeostatic Model Assessment of IR (HOMA-IR) and/or HTN and incorporated in the two models. For the IR index, the Area Under the Curve (AUC), sensitivity and specificity for identifying individuals above the 75th and 95th of HOMA-IR percentiles were 0.768 (95%CI: 0.721–0.815), 0.720 and 0.691 and 0.828 (95%CI: 0.766–0.890), 0.696 and 0.778 respectively. For the HTN index, the AUC, sensitivity and specificity were 0.778 (95%CI: 0.680–0.876), 0.667 and 0.797. The developed risk assessment tools are easy-to-apply, valid, and low-cost, identifying European adults at high risk for developing T2DM or having HTN

Megaesophagus in a Line of Transgenic Rats: A Model of Achalasia

Megaesophagus is defined as the abnormal enlargement or dilatation of the esophagus, characterized by a lack of normal contraction of the esophageal walls. This is called achalasia when associated with reduced or no relaxation of the lower esophageal sphincter (LES). To date, there are few naturally occurring models for this disease. A colony of transgenic (Pvrl3-Cre) rats presented with megaesophagus at 3 to 4 months of age; further breeding studies revealed a prevalence of 90% of transgene-positive animals having megaesophagus. Affected rats could be maintained on a total liquid diet long term and were shown to display the classic features of dilated esophagus, closed lower esophageal sphincter, and abnormal contractions on contrast radiography and fluoroscopy. Histologically, the findings of muscle degeneration, inflammation, and a reduced number of myenteric ganglia in the esophagus combined with ultrastructural lesions of muscle fiber disarray and mitochondrial changes in the striated muscle of these animals closely mimic that seen in the human condition. Muscle contractile studies looking at the response of the lower esophageal sphincter and fundus to electrical field stimulation, sodium nitroprusside, and L-nitro-L-arginine methyl ester also demonstrate the similarity between megaesophagus in the transgenic rats and patients with achalasia. No primary cause for megaesophagus was found, but the close parallel to the human form of the disease, as well as ease of care and manipulation of these rats, makes this a suitable model to better understand the etiology of achalasia as well as study new management and treatment options for this incurable condition.National Institutes of Health (U.S.) (Grant T32OD011141)National Institutes of Health (U.S.) (Grant P30ES002109

Dirac-Born-Infeld Action on the Tachyon Kink and Vortex

The tachyon effective field theory describing the dynamics of a non-BPS D-brane in superstring theory has an infinitely thin but finite tension kink solution describing a codimension one BPS D-brane. We study the world-volume theory of massless modes on the kink, and show that the world volume action has precisely the Dirac-Born-Infeld (DBI) form without any higher derivative corrections. We generalize this to a vortex solution in the effective field theory on a brane-antibrane pair. As in the case of the kink, the vortex is infinitely thin, has finite energy density, and the world-volume action on the vortex is again given exactly by the DBI action on a BPS D-brane. We also discuss the coupling of fermions and restoration of supersymmetry and $\kappa$-symmetry on the world-volume of the kink. Absence of higher derivative corrections to the DBI action on the soliton implies that all such corrections are related to higher derivative corrections to the original effective action on the world-volume of a non-BPS D-brane or brane-antibrane pair.Comment: LaTeX file, 34 pages; references and other minor comments adde