3,617 research outputs found

    Crossover from diffusive to strongly localized regime in two-dimensional systems

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    We have studied the conductance distribution function of two-dimensional disordered noninteracting systems in the crossover regime between the diffusive and the localized phases. The distribution is entirely determined by the mean conductance, g, in agreement with the strong version of the single-parameter scaling hypothesis. The distribution seems to change drastically at a critical value very close to one. For conductances larger than this critical value, the distribution is roughly Gaussian while for smaller values it resembles a log-normal distribution. The two distributions match at the critical point with an often appreciable change in behavior. This matching implies a jump in the first derivative of the distribution which does not seem to disappear as system size increases. We have also studied 1/g corrections to the skewness to quantify the deviation of the distribution from a Gaussian function in the diffusive regime.Comment: 4 pages, 4 figure

    C-GLOVES: An evaluation of the effectiveness of compression gloves in arthritis: a feasibility study : Hand assessment manual and glove treatment protocol 13.8.13v2

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    The C-Gloves compression glove feasibility study evaluated the effects of compression gloves on hand pain, stiffness, joint swelling, finger flexion, grip ability, grip strength and hand function. This manual includes the: inclusion/ exclusion criteria; glove treatment protocol; glove instruction sheet for patients; and protocols for conducting all assessments. These included: hand joint circumference (wrist, MCPs and PIP joints) using a Jobskin® tape measure; finger flexion measured using a 15cm ruler from the lateral nail fold to distal wrist crease (2nd=5th digits); and the Grip Ability Test (GAT). The latter was adapted for the right and left hands and the test procedure further standardised, including the use of the GAT MAT. The GAT MAT template is also located in the www.usir.salford.ac.uk depository and can be freely download

    Conservation practice could benefit from routine testing and publication of management outcomes

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    Effective conservation requires a step change in the way practitioners can contribute to science and can have access to research outputs. The journal Conservation Evidence was established in 2004 to help practitioners surmount several obstacles they face when attempting to document the effects of their conservation actions scientifically. It is easily and freely accessible online. It is free to publish in and it enables global communication of the effects of practical trials and experiments, which are virtually impossible to get published in most scientific journals. The driving force behind Conservation Evidence is the need to generate and share scientific information about the effects of interventions

    Improved theoretical prediction for the 2s hyperfine interval in helium ion

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    We consider the uncertainty of theoretical calculations for a specific difference of the hyperfine intervals in the 1s and 2s states in a light hydrogen-like atom. For a number of crucial radiative corrections the result for hydrogen atom and helium ion appears as an extrapolation of the numerical data from medium to low Z. An approach to a plausible estimation of the uncertainty is suggested using the example of the difference D21=8Ehfs(2s)Ehfs(1s)D_{21}= 8E_{hfs}(2s)-E_{hfs}(1s)

    One-loop self-energy correction to the 1s and 2s hyperfine splitting in H-like systems

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    The one-loop self-energy correction to the hyperfine splitting of the 1s and 2s levels in H-like low-Z atoms is evaluated to all orders in Z\alpha. The results are compared to perturbative calculations. The residual higher-order contribution is evaluated. Implications to the specific difference of the hyperfine structure intervals 8\Delta \nu_2 - \Delta \nu_1 in He^+ are investigated.Comment: 17 pages, RevTeX, 3 figure

    18F-fluorodeoxyglucose positron emission tomography/computed tomography and magnetic resonance imaging in patients with liver metastases from uveal melanoma: results from a pilot study.

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    PURPOSE: F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) and MRI are used for detecting liver metastases from uveal melanoma. The introduction of new treatment options in clinical trials might benefit from early response assessment. Here, we determine the value of FDG-PET/CT with respect to MRI at diagnosis and its potential for monitoring therapy. MATERIAL AND METHODS: Ten patients with biopsy-proven liver metastases of uveal melanoma enrolled in a randomized phase III trial (NCT00110123) underwent both FDG-PET coupled with unenhanced CT and gadolinium-diethylene triamine pentaacetic acid-enhanced liver MRI within 4 weeks. FDG-PET and MRI were evaluated blindly and then compared using the ratio of lesion to normal liver parenchyma PET-derived standardized uptake value (SUV). The influence of lesion size and response to chemotherapy were studied. RESULTS: Overall, 108 liver lesions were seen: 34 (31%) on both modalities (1-18 lesions/patient), four (4%) by PET/CT only, and 70 (65%) by MRI only. SUV correlated with MRI lesion size (r=0.81, P<0.0001). PET/CT detected 26 of 33 (79%) MRI lesions of more than or equal to 1.2 cm, whereas it detected only eight of 71 (11%) lesions of less than 1.2 cm (P<0.0001). MRI lesions without PET correspondence were small (0.6±0.2 vs. 2.1±1.1 cm, P<0.0001). During follow-up (six patients, 30 lesions), the ratio lesion-to-normal-liver SUV diminished in size-stable lesions (1.90±0.64-1.46±0.50, P<0.0001), whereas it increased in enlarging lesions (1.56±0.40-1.99±0.56, P=0.032). CONCLUSION: MRI outweighs PET/CT for detecting small liver metastases. However, PET/CT detected at least one liver metastasis per patient and changes in FDG uptake not related to size change, suggesting a role in assessing early therapy response

    Exciton-photon coupling in a ZnSe based microcavity fabricated using epitaxial liftoff

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    We report the observation of strong exciton-photon coupling in a ZnSe based microcavity fabricated using epitaxial liftoff. Molecular beam epitaxial grown ZnSe/Zn0.9_{0.9}Cd0.1_{0.1}Se quantum wells with a one wavelength optical length at the exciton emission were transferred to a SiO2_2/Ta2_2O5_5 mirror with a reflectance of 96% to form finesse matched microcavities. Analysis of our angle resolved transmission spectra reveals key features of the strong coupling regime: anticrossing with a normal mode splitting of 23.6meV23.6 meV at 20K20 K; composite evolution of the lower and upper polaritons; and narrowing of the lower polariton linewidth near resonance. The heavy hole exciton oscillator strength per quantum well is also deduced to be 1.78×1013cm21.78 \times 10^{13} cm^{-2}.Comment: 3 pages, 3 figure

    Performance of 18F-FET versus 18F-FDG-PET for the diagnosis and grading of brain tumors: systematic review and meta-analysis.

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    For the past decade (18)F-fluoro-ethyl-l-tyrosine (FET) and (18)F-fluoro-deoxy-glucose (FDG) positron emission tomography (PET) have been used for the assessment of patients with brain tumor. However, direct comparison studies reported only limited numbers of patients. Our purpose was to compare the diagnostic performance of FET and FDG-PET. We examined studies published between January 1995 and January 2015 in the PubMed database. To be included the study should: (i) use FET and FDG-PET for the assessment of patients with isolated brain lesion and (ii) use histology as the gold standard. Analysis was performed on a per patient basis. Study quality was assessed with STARD and QUADAS criteria. Five studies (119 patients) were included. For the diagnosis of brain tumor, FET-PET demonstrated a pooled sensitivity of 0.94 (95% CI: 0.79-0.98) and pooled specificity of 0.88 (95% CI: 0.37-0.99), with an area under the curve of 0.96 (95% CI: 0.94-0.97), a positive likelihood ratio (LR+) of 8.1 (95% CI: 0.8-80.6), and a negative likelihood ratio (LR-) of 0.07 (95% CI: 0.02-0.30), while FDG-PET demonstrated a sensitivity of 0.38 (95% CI: 0.27-0.50) and specificity of 0.86 (95% CI: 0.31-0.99), with an area under the curve of 0.40 (95% CI: 0.36-0.44), an LR+ of 2.7 (95% CI: 0.3-27.8), and an LR- of 0.72 (95% CI: 0.47-1.11). Target-to-background ratios of either FDG or FET, however, allow distinction between low- and high-grade gliomas (P > .11). For brain tumor diagnosis, FET-PET performed much better than FDG and should be preferred when assessing a new isolated brain tumor. For glioma grading, however, both tracers showed similar performances

    Students' syntactic mistakes in writing seven different types of SQL queries and its application to predicting students' success

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    © 2016 ACM. The computing education community has studied extensively the errors of novice programmers. In contrast, little attention has been given to student's mistake in writing SQL statements. This paper represents the first large scale quantitative analysis of the student's syntactic mistakes in writing different types of SQL queries. Over 160 thousand snapshots of SQL queries were collected from over 2000 students across eight years. We describe the most common types of syntactic errors that students make. We also describe our development of an automatic classifier with an overall accuracy of 0.78 for predicting student performance in writing SQL queries

    Myocardial blood flow quantification by Rb-82 cardiac PET/CT: A detailed reproducibility study between two semi-automatic analysis programs.

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    Several analysis software packages for myocardial blood flow (MBF) quantification from cardiac PET studies exist, but they have not been compared using concordance analysis, which can characterize precision and bias separately. Reproducible measurements are needed for quantification to fully develop its clinical potential. Fifty-one patients underwent dynamic Rb-82 PET at rest and during adenosine stress. Data were processed with PMOD and FlowQuant (Lortie model). MBF and myocardial flow reserve (MFR) polar maps were quantified and analyzed using a 17-segment model. Comparisons used Pearson's correlation ρ (measuring precision), Bland and Altman limit-of-agreement and Lin's concordance correlation ρc = ρ·C b (C b measuring systematic bias). Lin's concordance and Pearson's correlation values were very similar, suggesting no systematic bias between software packages with an excellent precision ρ for MBF (ρ = 0.97, ρc = 0.96, C b = 0.99) and good precision for MFR (ρ = 0.83, ρc = 0.76, C b = 0.92). On a per-segment basis, no mean bias was observed on Bland-Altman plots, although PMOD provided slightly higher values than FlowQuant at higher MBF and MFR values (P < .0001). Concordance between software packages was excellent for MBF and MFR, despite higher values by PMOD at higher MBF values. Both software packages can be used interchangeably for quantification in daily practice of Rb-82 cardiac PET
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