Analytic solution for kinetic equilibrium of beta-processes in nucleonic plasma with relativistic pairs

The analytic solution is obtained describing kinetic equilibrium of the $\beta$-processes in the nucleonic plasma with relativistic pairs. The nucleons $(n,p)$ are supposed to be non-relativistic and non-degenerate, while the electrons and positrons are ultra-relativistic due to high temperature $(T>6\cdot 10^9$K), or high density $(\rho>\mu 10^6$g/cm$^3$), or both, where $\mu$ is a number of nucleons per one electron. The consideration is simplified because of the analytic connection of the density with the electron chemical potential in the ultra-relativistic plasma, and Gauss representation of Fermi functions. Electron chemical potential and number of nucleons per one initial electron are calculated as functions of $\rho$ and $T$.Comment: 16 pages, 6 figure

Genetic Markers of Hereditary Thrombophilia and Risk of Thrombotic Complications in Patients with Polycythemia Vera

Background. Thrombotic complications are one of the main problems of polycythemia vera (PV) treatment. They significantly impair the quality of life of these patients and may lead to the lethal outcome. A thrombotic event often precedes the diagnosis of this hematological disease. The pathogenesis of thrombosis in myeloproliferative neoplasms, PV, in particular, is a complex one. Prescription of antiaggregants in the absence of thrombosis and anticoagulants after a thrombotic event requires special attention and development of corresponding recommendations. The prescription of anticoagulants is impossible without taking into account the risks of hemorrhagic complications, which are also typical for myeloproliferative neoplasms. Aim. Assessment of the impact of hereditary thrombophilia genetic markers on the risk of thrombotic complications in patients with PV. Methods. The study examined 116 patients with PV, who were screened for markers of hereditary thrombophilia: factor V (G1691A, FV Leiden), prothrombin, methylenetetrahydrofolate reductase (MTHFR), fibrinogen (FI), plasminogen activator inhibitor (PAI-1), and platelet fibrinogen receptor type IIIA (GPIIIA). The incidence of these markers and their role in thrombosis in such patients was investigated. Results. The study provided data on the incidence of hereditary thrombophilia markers in patients with PV. Statistically significant differences in the incidence of these markers and homocysteine level were found between patients with thrombosis and without them. Conclusion. The information about the hereditary thrombophilia markers presence may be useful for the prescription of adequate antiaggregant and anticoagulant therapy for PV patients. Further research in this field is justified and it will probably demonstrate the relevance of hereditary thrombophilia markers as prognostic factors for thrombotic complications risk assessment

Turbulence: new approaches

The authors present the results of numerical experiments carried out to examine the problem of development of turbulence and convection. On the basis of the results, they propose a physical model of the development of turbulence. Numerical algorithms and difference schema for carrying out numerical experiments in hydrodynamics, are proposed. Original algorithms, suitable for calculation of the development of the processes of turbulence and convection in different conditions, even on astrophysical objects, are presented. The results of numerical modelling of several important phenomena having both fundamental and applied importance are described