Spread of biological invasions: The experience of Tilapia species in the Shadegan Wetland, southwest of Iran

The status of non-native tilapia species was evaluated by sampling campaigns in fishing grounds in the central part of the Shadegan Wetland, southwest Iran in 2014–15 (with follow-up in 2019). Considering a high percentage of relative species abundance, the tilapia species (Coptodon zillii and Oreochromis aureus) are well established in the wetland. As the management plans of such species are difficult and expensive, prevention of the introduction of these species to other water bodies is highly recommended.Hussein Valikhani, Asghar Abdoli, Farshad Nejat, Milad Khosravi, Kamal Khezri, Bahram H. Kiab

Possibility of trout farms efluent return to groundwater In non-agricultural seasons

This project is trying to investigate water contamination after use in ponds. For this aquaculture status, physical and chemical water properties, microbial pollutants and heavy metals levels in the some of trout ponds effluent in East Azerbaijan province were evaluated in 2007 to 2009. The information of groundwater and climate conditions in ten years, Drilling and wells piezometric Information, in local wells are reviewed. According to data obtained from analysis of water samples in the output pools range studied concentrations(term mg/l) some parameters are as follows:(BOD: 1.9-3.2), (COD: 3.4-34.1), (TSS: 26.6-42.7), (N-NO_2:0.003-.136),(P-Po4:0.0170.067), (pH:7.75-8.28). Electrical conductivity (500 ±2 to 1129±144 term µm/cm) in the effluent ponds. Based on the results of we can say that between input and effluent ponds in the review of all factors as chlorine, sulfate, sodium, potassium, total nitrogen, soluble phosphorus, total phosphorus, calcium, total hardness, magnesium, alkalinity and silica significant changes not be observed. Review of water analysis data to some factors (such as: water temperature, EC, pH, NO_2, CO_2, HCO_3, CO_3, DO, COD, BOD) and compare this data with the authorities standard confirmed that the All factors mentioned in effluent is allowed now. In terms of microbial contamination and heavy metals (Zn, Cu, Ca, Pb, Fe, Cr) is no pollution. Appropriate strategies for removing suspended materials must to use. We can use Watershed Management solutions to inject output water to the underground table. Should be noted status change (eg change in flow rate, an unusual increase in temperature, fish density increasing, reducing food quality, lack of appropriate management actions and ...) may reduce the effluent quality and the ability of injection water underground to lose. In this case, measures must be for wastewater treatment and improve the quality ponder

Pemphigus autoimmunity: Hypotheses and realities

The goal of contemporary research in pemphigus vulgaris and pemphigus foliaceus is to achieve and maintain clinical remission without corticosteroids. Recent advances of knowledge on pemphigus autoimmunity scrutinize old dogmas, resolve controversies, and open novel perspectives for treatment. Elucidation of intimate mechanisms of keratinocyte detachment and death in pemphigus has challenged the monopathogenic explanation of disease immunopathology. Over 50 organ-specific and non-organ-specific antigens can be targeted by pemphigus autoimmunity, including desmosomal cadherins and other adhesion molecules, PERP cholinergic and other cell membrane (CM) receptors, and mitochondrial proteins. The initial insult is sustained by the autoantibodies to the cell membrane receptor antigens triggering the intracellular signaling by Src, epidermal growth factor receptor kinase, protein kinases A and C, phospholipase C, mTOR, p38 MAPK, JNK, other tyrosine kinases, and calmodulin that cause basal cell shrinkage and ripping desmosomes off the CM. Autoantibodies synergize with effectors of apoptotic and oncotic pathways, serine proteases, and inflammatory cytokines to overcome the natural resistance and activate the cell death program in keratinocytes. The process of keratinocyte shrinkage/detachment and death via apoptosis/oncosis has been termed apoptolysis to emphasize that it is triggered by the same signal effectors and mediated by the same cell death enzymes. The natural course of pemphigus has improved due to a substantial progress in developing of the steroid-sparing therapies combining the immunosuppressive and direct anti-acantholytic effects. Further elucidation of the molecular mechanisms mediating immune dysregulation and apoptolysis in pemphigus should improve our understanding of disease pathogenesis and facilitate development of steroid-free treatment of patients

Numerical Modelling of Concrete-to-UHPC Bond Strength

Ultra-High Performance Concrete (UHPC) has been a material of interest for retrofitting reinforced concrete elements because of its pioneer mechanical and material properties. Numerous experimental studies for retrofitting concrete structures have shown an improvement in durability performance and structural behaviour. However, conservative and sometimes erroneous estimates for bond strength are used for numerically calculating the strength of the composite members. In addition, different roughening methods have been used to improve the bond mechanism; however, there is a lack of numerical simulation for the force transfer mechanism between the concrete substrate and UHPC as a repair material. This paper presents an experimental and numerical programme designed to characterize the interfacial properties of concrete substrate and its effect on the bond strength between the two materials. The experimental programme evaluates the bond strength between the concrete substrates and UHPC with two different surface preparations while using bi-surface test and additional material tests, including cylinder and cube tests for compression property, direct tension test, and flexural test to complement UHPC tensile properties. Non-linear finite element analysis was conducted, which uses a numerical zero thickness volume model to define the interface bond instead of a traditional fixed contact model. The numerical results from the zero thickness volume model show good agreement with the experimental results with a reduction in error by 181% and 24% for smooth and rough interface surfaces if compared to the results from the model with a fixed contact