276 research outputs found
Expression of a rice chitinase gene in transgenic banana ('Gros Michel', AAA genome group) confers resistance to black leaf streak disease
Peer reviewe
El siguiente paso en educación neurológica en el Perú: Un llamado para la formación de subespecialidades.
Efficiency and genotypic quality potential of winter wheat grain in the central chernozem region
Winter wheat in Russia occupies more than half of the sown areas of grain crops and more than 70% of winter crops. Advanced farms with a high culture of farming (crop rotations, fertilisers, soil treatment, etc.). The yield of this crop is more than 40 kg per 1 ha. One of the reasons is the lack of scientifically substantiated varietal technology of cultivation of this crop in relation to soil-climatic and regional zones. As subjects of research, promising varieties, Skipetr,Moscovskaya 56, and Zorro were used. The research was conducted in 2020-2022 in the conditions of the foothill zone of the farm “Dubovitskoe” Maloarkhangelsky district of Orel region. The paper considers the economic value of the variety, which is determined by the totality of biological and technological, food, and baking properties of high-quality varieties of agricultural crops. The choice of high-quality varieties of winter wheat and the use of the genetic resource of the variety is a decisive factor in increasing the yield of many agricultural crops, including winter wheat. When selecting the seed, it is worthwhile to assess it competently and understand all the risks of its cultivation. For many years, breeders around the world have been working on developing new productive and productive varieties. Much attention should be paid to the adaptive adaptation of varieties to external environmental conditions, which will depend on how much stable it will be possible to obtain for the programmed yield. The result of the work done shows that the new varieties under study are not inferior but superior to the control variety, which was required to be proved
Chromoplast Biogenesis in Cucumis sativus Corollas (Rapid Effect of Gibberellin A3 on the Accumulation of a Chromoplast-Specific Carotenoid-Associated Protein)
Isolation and Regulation of Accumulation of a Minor Chromoplast-Specific Protein from Cucumber Corollas
Prenatal Polycyclic Aromatic Hydrocarbon (PAH) Exposure and Child Behavior at Age 6–7 Years
Background: Airborne polycyclic aromatic hydrocarbons (PAH) are widespread urban air pollutants from fossil fuel burning and other combustion sources. We previously reported that a broad spectrum of combustion-related DNA adducts in cord blood was associated with attention problems at 6–7 years of age in the Columbia Center for Children’s Environmental Health (CCCEH) longitudinal cohort study
Predictors and consequences of global DNA methylation in cord blood and at three years.
DNA methylation changes have been implicated in many common chronic diseases leading to the hypothesis that environmental and age-related DNA methylation changes within individuals are involved in disease etiology. Few studies have examined DNA methylation changes within an individual over time and all of these studies have been conducted in adults. Here, we aim to characterize how global DNA methylation changes from birth to age three within a longitudinal birth cohort study and to determine whether there are consistent predictors of DNA methylation levels measured three years apart. We measured global DNA methylation in the same children at birth (cord blood) and again at three years of age among 165 children, using an immunoassay. We found that on average, DNA methylation was significantly higher in blood at age 3-years than in cord blood (p<0.01). However, for any individual child, the difference was less than would be expected by chance. We found that pre-pregnancy BMI was negatively predictive of both cord and three-year DNA methylation, even after statistical adjustment to account for the correlation between cord blood and three-year DNA methylation. The biologic implications of small changes in global DNA methylation are unknown. However, the observation that global DNA methylation levels persist within an individual from birth to age three supports the belief that factors that influence global DNA methylation, including pre-pregnancy BMI, may confer long-term effects.VoRSUNY DownstateEnvironmental and Occupational Health SciencesN/
Predictors and Consequences of Global DNA Methylation in Cord Blood and at Three Years
DNA methylation changes have been implicated in many common chronic diseases leading to the hypothesis that environmental and age-related DNA methylation changes within individuals are involved in disease etiology. Few studies have examined DNA methylation changes within an individual over time and all of these studies have been conducted in adults. Here, we aim to characterize how global DNA methylation changes from birth to age three within a longitudinal birth cohort study and to determine whether there are consistent predictors of DNA methylation levels measured three years apart. We measured global DNA methylation in the same children at birth (cord blood) and again at three years of age among 165 children, using an immunoassay. We found that on average, DNA methylation was significantly higher in blood at age 3-years than in cord blood (p&0.01). However, for any individual child, the difference was less than would be expected by chance. We found that pre-pregnancy BMI was negatively predictive of both cord and three-year DNA methylation, even after statistical adjustment to account for the correlation between cord blood and three-year DNA methylation. The biologic implications of small changes in global DNA methylation are unknown. However, the observation that global DNA methylation levels persist within an individual from birth to age three supports the belief that factors that influence global DNA methylation, including pre-pregnancy BMI, may confer long-term effects
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