Meson Masses and Mixing Angles in 2+1 Flavor Polyakov Quark Meson Sigma Model and Symmetry Restoration Effects

The meson masses and mixing angles have been calculated for the scalar and pseudoscalar sector in the framework of the generalized 2+1 flavor Polyakov loop augmented quark meson linear sigma model. We have given the results for two different forms of the effective Polyakov loop potential. The comparison of results with the existing calculations in the bare 2+1 quark meson linear sigma model, shows that the restoration of chiral symmetry becomes sharper due to the influence of the Polyakov loop potential. We find that inclusion of the Polyakov loop in quark meson linear sigma model together with the presence of axial anomaly, triggers an early and significant melting of the strange condensate. We have examined how the inclusion of the Polyakov loop qualitatively and quantitatively affects the convergence in the masses of the chiral partners in pseudoscalar ($\pi$, $\eta$, $\eta'$, $K$) and scalar ($\sigma$, $a_0$, $f_0$,$\kappa$) meson nonets as the temperature is varied on the reduced temperature scale. The role of $U_A(1)$ anomaly in determining the isoscalar masses and mixing angles for the pseudoscalar ($\eta$ and $\eta'$) and scalar ($\sigma$ and $f_0$)meson complex, has also been investigated in the Polyakov quark meson linear sigma model. The interplay of chiral symmetry restoration effects and the setting up of $U_A(1)$ restoration trend has been discussed and analyzed in the framework of the presented model calculations.Comment: 15 pages, 8 figures, 4 table

Study Of Phenothiazine On p53 Core Domain Mutant Y220C: Finding The Anti-tumor Activity Of Phenothiazine

The tumor suppressor protein p53 is a transcription factor that plays a key role in the prevention of cancer development. The p53 cancer mutation Y220C induces formation of a cavity on the protein's surface that can accommodate stabilizing small molecules. We have attempted with the help of virtual screening and molecular docking approach using Lamarckian Genetic Algorithm to elucidate the extent of specificity of p53 cancer mutation Y220C towards different class of Phenothiazines (an anti-cancer agent). 

The 393 residue p53 tumor suppressor protein exists in a dynamic equilibrium to form homotetramers. Each chain comprises several functional domains. The N terminal part of the protein consists of the trans-activation domain (residues 1–63) followed by a proline rich region (64– 92). The central (core) domain (p53 core domain) is responsible for binding. The C terminal part of p53 contains the tetramerization domain (residues 326–355) and the negative regulatory domain at the extreme C terminus (363–393), which contains phosphorylation and acetylation sites and regulates the DNA binding activity of p53.

The docking result of the study of 2,000 Phenothiazines demonstrated that the binding energies were in the range of -10.54 kcal/mol to -1.14 kcal/mol, with 8 molecules showing hydrogen bonds with the active site residues (Lys 164). All the selected 2000 inhibitors were selected on the basis of the structural specificity to the enzyme towards its substrate and inhibitors. Our research provides a blueprint for the design of more potent and specific drugs that rescue p53-Y220C

Improve performance of fast steady state response for DC servo motor by fuzzy logic implementation

The DC Servo Motors has top position in various servomechanisms. It is important to study DC Servo motor along with its position control study. Generally transient responses of DC Servo Motor are improved by using PID controller. Currently, to provide workable initial value most tuning methods have been designed. The workable initial value further manually corrected for special requirement. The work presents fast tuning and flexible method which is based on Fuzzy logic. The GA (genetic algorithm) is used to determine some optimal parameter of PID controller. In this paper simulation results shows Fuzzy logic satisfied with wide range of requirement with compared to the tuning method. Fuzzy logic gives the actual response with respect to required response . DOI: 10.17762/ijritcc2321-8169.15068

Enhanced Transmission and Receiver Diversity in Orthogonal Frequency Division Multiplex Systems using Blind Channel Estimation

This paper deals with the blind channel estimation technique in OFDM system with receiver diversity to analyze the bit error rate with respect to the number of symbols. The paper clearly brings out the advantage that is being offered by the use of Blind channel estimation technique in terms of SNR requirements. Also a comparative study has been made for the analysis of BER variation with the amount i.e. number of symbols being transmitted. The work also explores the possibility of obtaining an optimum value of number of receivers that may lead to desired BER for threshold value of SNR in an OFDM system

A Summative Comparison of Blind Channel Estimation Techniques for Orthogonal Frequency Division Multiplexing Systems

The OFDM techniquei.e. Orthogonal frequency division multiplexing has become prominent in wireless communication since its instruction in 1950’s due to its feature of combating the multipath fading and other losses. In an OFDM system, a large number of orthogonal, overlapping, narrow band subchannels or subcarriers, transmitted in parallel, divide the available transmission bandwidth. The separation of the subcarriers is theoretically optimal such that there is a very compact spectral utilization. This paper reviewed the possible approaches for blind channel estimation in the light of the improved performance in terms of speed of convergence and complexity. There were various researches which adopted the ways for channel estimation for Blind, Semi Blind and trained channel estimators and detectors. Various ways of channel estimation such as Subspace, iteration based, LMSE or MSE based (using statistical methods), SDR, Maximum likelihood approach, cyclostationarity, Redundancy and Cyclic prefix based. The paper reviewed all the above approaches in order to summarize the outcomes of approaches aimed at optimum performance for channel estimation in OFDM system

Dynamic Instruction Scheduling For Microprocessors Having Out Of Order Execution

Dynamic Instruction Scheduling is very much needed for fast working of multiprocessor and reduction of overhead by the processor. The Instruction scheduling logic mainly depends on associative searching of the entries to the dynamic wakeup instructions for the execution. We also describes the scheduler concept which also the concern for scalability and complexity of the multiprocessor. We have different Dynamic Instruction Scheduling Logic highlighting the objectives, goals, advantages and challenges facing during scheduling logic like energy issues and complexity issues as well as full description of dynamic instruction Scheduling logic. In this paper, we will be presented in a comprehensive analysis to reschedule the execution order of instructions for improve the performance of microprocessor. General Terms: Design, Performance, Measurement Keywords: Dynamic Instruction Scheduling, Instruction Grouping, Issue Queue

Electronic structure of Pr2MnNiO6 from x-ray photoemission, absorption and density functional theory

The electronic structure of double perovskite Pr2MnNiO6 is studied using core x-ray photoelectron spectroscopy and x-ray absorption spectroscopy. The 2p x-ray absorption spectra show that Mn and Ni are in 2+ and 4+ states respectively. Using charge transfer multiplet analysis of Ni and Mn 2p XPS spectra, we find charge transfer energies {\Delta} of 3.5 and 2.5 eV for Ni and Mn respectively. The ground state of Ni2+ and Mn4+ reveal a higher d electron count of 8.21 and 3.38 respectively as compared to the atomic values of 8.00 and 3.00 respectively thereby indicating the covalent nature of the system. The O 1s edge absorption spectra reveal a band gap of 0.9 eV which is comparable to the value obtained from first principle calculations for U-J >= 2 eV. The density of states clearly reveal a strong p-d type charge transfer character of the system, with band gap proportional to average charge transfer energy of Ni2+ and Mn4+ ions.Comment: 18 pages, 9 figure