A Total Product System Concept - a case study of the smart (tm) automobile

Increasing demand from consumers plus EU legislation has raised awareness within the automotive production sector of the urgent need to reduce the environmental impacts from the three main stages in vehicle life – car manufacture, car use and end-of life vehicle processing. The paper reviews how the originator and manufacturer of the smart automobile has worked directly with its main system partners to address environmental issues in these three stages while optimizing performance across the parameters of commercial viability. This required the creation of strategic relationships within the supply chain. Overall, this innovative approach is viewed in the context of a total product system. The smart car highlights the following critical areas: use of modularity in product design and production facility layout; emphasis on partner participation from product creation to after-sales; and the use of highly customised build-to-order product system to 'green' the entire supply chain. In particular, the case study compares the process characteristics empoyed at the smart car factory, called 'smartville', with more traditional approaches to vehicle manufacture. It exmaines these issues in a preliminary attempt to establish the actual or potential reduction of environmental impact in the three stages of vehicle life, including the role of main suppliers in this process

Accounting for indebtedness: geopolitics, technocracy and advanced financial capital

This paper explores the role of accounting within the context of Lazzarato’s theorization of indebtedness. Accounting is often depicted as neutral, objective and technocratic, and despite Lazzarato referencing accounting within his exploration of indebtedness, we believe the role of accounting is underexplored in his analyses. Our intervention suggests that accounting is the primary language of financialisation, securitization, financial capital and indebtedness. This paper also extends Lazzarato’s thesis by arguing that, with new accounting technologies, indebtedness is being spread to emerging economies. This extension is mobilized through the work of the International Accounting Standards Board, as a private accounting standard setter, in partnership with the World Bank and the International Monetary Fund as accounting is language of advanced financial accounting and indebtedness

The effects of ganglionic and adrenergic blockade on the circulation of the young chimpanzee Final technical report, 1 Oct. 1963 - 30 Apr. 1965

Ganglionic and adrenergic blockade effects on circulatory system studied on young chimpanze

Rurality or distance to care and the risk of homelessness among Afghanistan and Iraq veterans

INTRODUCTION: To date, no studies have examined the relationship of rurality and distance to nearest VA facility to risk of homelessness. METHODS: We examined differences in the rate of homelessness within a year of a Veteran's first encounter with the VA following last military separation based on rurality and distance to the nearest VA facility using multivariable log-binomial regressions. RESULTS: In our cohort of 708,120 Veterans, 73% were determined to have a forwarding address in urban areas, 59.2% and 86.7% lived within 40 miles of the nearest VA medical center (VAMC), respectively. Veterans living in a rural area and those living between 20+ miles away from the nearest VAMC were at a lower risk for homelessness. CONCLUSIONS: Our unique dataset allowed us to explore the relationship between geography and homelessness. These results are important to policy makers in understanding the risk factors for homelessness among Veterans and planning interventions

Two New Tidally Distorted White Dwarfs

We identify two new tidally distorted white dwarfs (WDs), SDSS J174140.49+652638.7 and J211921.96-001825.8 (hereafter J1741 and J2119). Both stars are extremely low mass (ELM, < 0.2 Msun) WDs in short-period, detached binary systems. High-speed photometric observations obtained at the McDonald Observatory reveal ellipsoidal variations and Doppler beaming in both systems; J1741, with a minimum companion mass of 1.1 Msun, has one of the strongest Doppler beaming signals ever observed in a binary system (0.59 \pm 0.06% amplitude). We use the observed ellipsoidal variations to constrain the radius of each WD. For J1741, the star's radius must exceed 0.074 Rsun. For J2119, the radius exceeds 0.10 Rsun. These indirect radius measurements are comparable to the radius measurements for the bloated WD companions to A-stars found by the Kepler spacecraft, and they constitute some of the largest radii inferred for any WD. Surprisingly, J1741 also appears to show a 0.23 \pm 0.06% reflection effect, and we discuss possible sources for this excess heating. Both J1741 and J2119 are strong gravitational wave sources, and the time-of-minimum of the ellipsoidal variations can be used to detect the orbital period decay. This may be possible on a timescale of a decade or less.Comment: 6 pages, 4 figures, accepted for publication in the Astrophysical Journa

Paleocurrent reconstruction of the deep Pacific inflow during the middle Miocene : reflections of East Antarctic Ice Sheet growth

Today the deep western boundary current (DWBC) east of New Zealand is the most important route for deep water entering the Pacific Ocean. Large-scale changes in deep water circulation patterns are thought to have been associated with the development of the East Antarctic Ice Sheet (EAIS) close to the main source of bottom water for the DWBC. Here we reconstruct the changing speed of the southwest Pacific DWBC during the middle Miocene from ∼15.5-12.5 Ma, a period of significant global ice accumulation associated with EAIS growth. Sortable silt mean grain sizes from Ocean Drilling Program Site 1123 reveal variability in the speed of the Pacific inflow on the timescale of the 41 kyr orbital obliquity cycle. Similar orbital period flow changes have recently been demonstrated for the Pleistocene epoch. Collectively, these observations suggest that a strong coupling between changes in the speed of the deep Pacific inflow and high-latitude climate forcing may have been a persistent feature of the global thermohaline circulation system for at least the past 15 Myr. Furthermore, long-term changes in flow speed suggest an intensification of the DWBC under an inferred increase in Southern Component Water production. This occurred at the same time as decreasing Tethyan outflow and major EAIS growth between ∼15.5 and 13.5 Ma. These results provide evidence that a major component of the deep thermohaline circulation was associated with the middle Miocene growth of the EAIS and support the view that this time interval represents an important step in the development of the Neogene icehouse climate

No man’s land: information needs and resources of men with metastatic castrate resistant prostate cancer

The majority of men treated for prostate cancer will eventually develop castrate resistant disease (CRPC) with metastases (mCRPC). There are several options for further treatment: chemotherapy, third-line hormone therapy, radium, immunotherapy and palliation. Current ASCO guidelines for survivors of prostate cancer recommend that an individual’s information needs at all stages of disease are assessed, and that patients are provided with or referred to the appropriate sources for information and support. Earlier reviews have highlighted the dearth of such services and we wished to see if the situation had improved more recently. Unfortunately we conclude that there is still a lack of good quality congruent information easily accessible specifically for men with mCRPC and insufficient data regarding the risks, harms and benefits of different management plans. More research providing a clear evidence base about treatment consequences using patient reported outcome measures is required

A modern critic: Stuart Pratt Sherman

Thesis (M.A.)--Boston University, 1939. This item was digitized by the Internet Archive

The Shape of Galaxy Cluster Dark Matter Haloes: Systematics of Its Imprint on Cluster Gas, and Comparison to Observations

(Abridged) We study predictions for galaxy cluster observables that can test the statistics of dark matter halo shapes expected in a flat LCDM universe. We present a simple analytical model for the prediction of cluster-scale X-ray observations, approximating clusters as isothermal systems in hydrostatic equilibrium, and dark matter haloes as ellipsoids with uniform axial ratios. We test the model against high-resolution, hydrodynamic cluster simulations to gauge its reliability. We find that this simple prescription does a good job of predicting the distribution of cluster X-ray ellipticities compared to the simulations as long as one focuses on cluster regions that are less sensitive to recent mergers. Based on this simple model, the distribution of cluster-size halo shapes expected in the concordance LCDM cosmology implies an X-ray ellipticity distribution with a mean of 0.32 +- 0.01 and a scatter of 0.14 +- 0.01 for the mass range (1-4)x10^{14} Msun/h. We find it important to include the mass dependence of halo shape to make comparisons to observational samples that contain many, very massive clusters. We analyse the systematics of four observational samples of cluster ellipticities and find that our results are statistically compatible with observations. In particular, we find remarkably good agreement between two recent ROSAT samples and LCDM predictions that DO NOT include gas cooling. We also test how well our analytical model can predict Sunyaev-Zel'dovich decrement maps and find that it is less successful although still useful; the model does not perform as well as a function of flux level in this case because of the changing triaxiality of dark matter haloes as a function of radial distance. Both this effect and the changing alignment of isodensity shells of dark matter haloes leave an imprint on cluster gas...Comment: 16 pages, 9 figures; corrected typo (no result affected) submitted to MNRA

Nuclear medicine procedures and the evaluation of male sexual organs: a short review

Sexuality consists of three aspects that are interrelated and inseparable, biological, physiological and social. The biological aspect considers the individual's capability to give and to receive pleasure. In consequence, it covers the functionality of the sexual organs and the physiology of human sexual response cycle. Diagnostic imaging modalities, such as single photon emission computed tomography (SPECT) and positron emission tomography (PET) have been used to evaluate clinical disorders of the male reproductive system. PET and SPECT procedures basically involve the administration of a radiopharmaceutical that has a higher uptake in a specific tumor or tissue. The aim of this brief review is to present some radiopharmaceuticals that have been used in the clinical evaluation of the male sexual organs (testes, prostate, seminal vesicles, penis) related with male sexuality. This information could be useful in better understanding the male sexual response cycle, as well as the sexual disorders, when considering the male sexual organs and the pelvic floor. Moreover, the findings obtained with PET and SPECT imaging could help to evaluate the efficacy of clinical results of therapeutic procedures. In conclusion, the knowledge from these images could aid in better understanding the physiology of the different organs related with sexuality. Furthermore, they could be important tools to evaluate the physiological integrity of the involved organs, to improve clinical strategies and to accompany the patients under treatment