Evaluation of Radiant Heating Ceiling Based on Energy and Thermal Comfort Criteria, Part II: A Numerical Study

Large-surface radiant heating ceiling systems favor energy-efficient solutions on the heat generation side because of the relatively low temperature of the heat transfer medium. Additionally, their application in the renovation of existing buildings is relatively uncomplicated and requires minimal changes to the building’s construction. However, ASHRAE Standard-55 and former studies by Fanger indicated that among large-surface radiant systems, the highest percentage of dissatisfaction for an equal radiant temperature asymmetry (RTA) was reported for a warm ceiling. The maximum RTA of 4 K corresponding to 5% of dissatisfaction was suggested. In the first part of our study (subjective experiments), we have suggested the RTA of about 7.4 K if occupants have winter clothing (Safizadeh et al., 2018). However, former studies tested radiant ceiling systems at different temperatures in “neutral conditions” with a constant operative temperature, which rarely occurs in reality. Accordingly, the goal of this study is to evaluate the potential application of low-temperature radiant heating ceilings in a building with low- and high-performance facades using steady-state simulations with a coupled CFD–thermal comfort model and transient simulations using TRNSYS. Forty combinations of simulation scenarios including six ceiling surface temperatures (20 °C, 25 °C, 28 °C, 33 °C, 38 °C, and 45 °C), two low- and high-performance facades, two rooms with one and two facades, and distances of 1 m and 3 m to the window were examined. The findings of this research show that the supply water temperatures between 28–45 °C from a heat pump are ideal for a building with a high-performance façade. Additionally, the results suggest that ceiling temperatures as low as 20–25 °C in renovated buildings and 25–28 °C in a building with low-performance facades can provide optimal thermal sensations at most body parts. This study also proves that the PMV comfort model (Predicted Mean Vote index) is not at all a suitable model for the evaluation of radiant heating systems (especially if occupants have winter clothes), even if the air/operative temperature distribution near an occupant is uniform

the unusual metal ion binding ability of histidyl tags and their mutated derivatives

Peptides that consist of repeated sequences of alternating histidines and alanines strongly bind Cu(ii) and form α-helical structures

Tattoo as art - history and reasons for tattooing

W niniejszej pracy licencjackiej poruszany jest temat tatuażu. Celem pracy jest przedstawienie tatuażu jako formy sztuki oraz pokazanie jego zjawiska jako rzeczy bardziej złożonej niż tylko obrazek namalowany na ciele. W pracy została opisana historia tatuażu na świecie jak i w Polsce, jego funkcje oraz rodzaje. Została również poruszona kwestia tatuażu a tożsamości i jego wpływu na jej kształtowanie. Ważną częścią pracy również są wyniki ankiety przeprowadzonej na temat powodów tatuowania się, gdzie opisane są ów powody oraz pokazane jest jak społeczeństwo nadal w sposób stereotypowy reaguje na osoby posiadające tatuaże.In this BA thesis, the topic of tattooing is being discussed. The aim of this paper is to present tattoos as a form of art and to show that it is a more complex thing than just a picture painted on the body. The work describes the history of tattooing in the world and in Poland, its functions and types. The issue of a tattoo and its identity and influence on its shaping was also raised. An important part of the work was also the results of the conducted survey on the reasons for tattooing, which describes the reasons and shows how the society still stereotypes people with tattoos

Evaluation of Radiant Heating Ceiling Based on Energy and Thermal Comfort Criteria, Part II: A Numerical Study

Large-surface radiant heating ceiling systems favor energy-efficient solutions on the heat generation side because of the relatively low temperature of the heat transfer medium. Additionally, their application in the renovation of existing buildings is relatively uncomplicated and requires minimal changes to the building’s construction. However, ASHRAE Standard-55 and former studies by Fanger indicated that among large-surface radiant systems, the highest percentage of dissatisfaction for an equal radiant temperature asymmetry (RTA) was reported for a warm ceiling. The maximum RTA of 4 K corresponding to 5% of dissatisfaction was suggested. In the first part of our study (subjective experiments), we have suggested the RTA of about 7.4 K if occupants have winter clothing (Safizadeh et al., 2018). However, former studies tested radiant ceiling systems at different temperatures in “neutral conditions” with a constant operative temperature, which rarely occurs in reality. Accordingly, the goal of this study is to evaluate the potential application of low-temperature radiant heating ceilings in a building with low- and high-performance facades using steady-state simulations with a coupled CFD–thermal comfort model and transient simulations using TRNSYS. Forty combinations of simulation scenarios including six ceiling surface temperatures (20 °C, 25 °C, 28 °C, 33 °C, 38 °C, and 45 °C), two low- and high-performance facades, two rooms with one and two facades, and distances of 1 m and 3 m to the window were examined. The findings of this research show that the supply water temperatures between 28–45 °C from a heat pump are ideal for a building with a high-performance façade. Additionally, the results suggest that ceiling temperatures as low as 20–25 °C in renovated buildings and 25–28 °C in a building with low-performance facades can provide optimal thermal sensations at most body parts. This study also proves that the PMV comfort model (Predicted Mean Vote index) is not at all a suitable model for the evaluation of radiant heating systems (especially if occupants have winter clothes), even if the air/operative temperature distribution near an occupant is uniform.</jats:p

Evaluation of Radiant Heating Ceiling Based on Energy and Thermal Comfort Criteria, Part II: A Numerical Study

Large-surface radiant heating ceiling systems favor energy-efficient solutions on the heat generation side because of the relatively low temperature of the heat transfer medium. Additionally, their application in the renovation of existing buildings is relatively uncomplicated and requires minimal changes to the building&rsquo;s construction. However, ASHRAE Standard-55 and former studies by Fanger indicated that among large-surface radiant systems, the highest percentage of dissatisfaction for an equal radiant temperature asymmetry (RTA) was reported for a warm ceiling. The maximum RTA of 4 K corresponding to 5% of dissatisfaction was suggested. In the first part of our study (subjective experiments), we have suggested the RTA of about 7.4 K if occupants have winter clothing (Safizadeh et al., 2018). However, former studies tested radiant ceiling systems at different temperatures in &ldquo;neutral conditions&rdquo; with a constant operative temperature, which rarely occurs in reality. Accordingly, the goal of this study is to evaluate the potential application of low-temperature radiant heating ceilings in a building with low- and high-performance facades using steady-state simulations with a coupled CFD&ndash;thermal comfort model and transient simulations using TRNSYS. Forty combinations of simulation scenarios including six ceiling surface temperatures (20 &deg;C, 25 &deg;C, 28 &deg;C, 33 &deg;C, 38 &deg;C, and 45 &deg;C), two low- and high-performance facades, two rooms with one and two facades, and distances of 1 m and 3 m to the window were examined. The findings of this research show that the supply water temperatures between 28&ndash;45 &deg;C from a heat pump are ideal for a building with a high-performance fa&ccedil;ade. Additionally, the results suggest that ceiling temperatures as low as 20&ndash;25 &deg;C in renovated buildings and 25&ndash;28 &deg;C in a building with low-performance facades can provide optimal thermal sensations at most body parts. This study also proves that the PMV comfort model (Predicted Mean Vote index) is not at all a suitable model for the evaluation of radiant heating systems (especially if occupants have winter clothes), even if the air/operative temperature distribution near an occupant is uniform

Poly-Xaa Sequences in Proteins - Biological Role and Interactions with Metal Ions: Chemical and Medical Aspects

Background: The understanding of the bioinorganic and coordination chemistry of metalloproteins containing unusual poly-Xaa sequences, in which a single amino acid is repeated consecutively, is crucial for describing their metal binding-structure-function relationship, and therefore also crucial for understanding their medicinal potential. To the best of our knowledge, this is the first systematic review on metal complexes with polyXaa sequences. Methods: We performed a thorough search of high quality peer reviewed literature on poly-Xaa type of sequences in proteins, focusing on their biological importance and on their interactions with metal ions. Results: 228 papers were included in the review. More than 70% of them discussed the role of metal complexes with the studied types of sequences. In this work, we showed numerous medically important and chemically fascinating examples of possible ‘poly-Xaa' metal binding sequences. Conclusion: Poly-Xaa sequences, in which a single amino acid is repeated consecutively, are often not only tempting binding sites for metal ions, but very often, together with the bound metal, serve as structure determinants for entire proteins. This, in turn, can have consequences for the whole organism. Such sequences in bacterial metal chaperones can be a possible target for novel, antimicrobial therapeutics. </jats:sec

AGHLDDLPGALSAL: A hemoglobin fragment potentially competing with albumin to bind transition metal ions

Protein degradation leads to the formation of endogenous peptides, the biological activity of which is most often unknown. The peptide AGHLDDLPGALSAL, recently isolated from mouse brain homogenates, has been recognized as a fragment of the α-chain of hemoglobin. AGHLDDLPGALSAL has the ability of inhibiting the peripheral hyperalgesic inflammatory responses through the indirect activation of the μ-opioid receptors. A peculiarity of AGHLDDLPGALSAL is the presence, at its N-terminus of a strong binding site for divalent transition metal ions, similar to that characterizing the human albumin and called “ATCUN motif”. The consequential metal binding ability of AGHLDDLPGALSAL can be connected to its biological activity. For this reason, we decided to investigate the coordination properties of AGHLDDLPGALSAL towards Cu(II), Ni(II) and Zn(II) ions, reported here for the first time. The results confirm that AGHLDDLPGALSAL is a strong ligand for those metals: it can even compete with albumin under suitable conditions. In vitro assays on the inhibition of Cu(II) toxicity towards different cell lines confirmed that the binding ability of AGHLDDLPGALSAL can imply relevant biological consequences