1,826 research outputs found
Large emergency-response exercises: qualitative characteristics - a survey
Exercises, drills, or simulations are widely used, by governments, agencies and commercial organizations, to simulate serious incidents and train staff how to respond to them. International cooperation has led to increasingly large-scale exercises, often involving hundreds or even thousands of participants in many locations. The difference between ‘large’ and ‘small’ exercises is more than one of size: (a) Large exercises are more ‘experiential’ and more likely to undermine any model of reality that single organizations may create; (b) they create a ‘play space’ in which organizations and individuals act out their own needs and identifications, and a ritual with strong social implications; (c) group-analytic psychotherapy suggests that the emotions aroused in a large group may be stronger and more difficult to control. Feelings are an unacknowledged major factor in the success or failure of exercises; (d) successful large exercises help improve the nature of trust between individuals and the organizations they represent, changing it from a situational trust to a personal trust; (e) it is more difficult to learn from large exercises or to apply the lessons identified; (f) however, large exercises can help develop organizations and individuals. Exercises (and simulation in general) need to be approached from a broader multidisciplinary direction if their full potential is to be realized
On Hoyle-Narlikar-Wheeler mechanism of vibration energy powered magneto-dipole emission of neutron stars
We revisit the well-known Hoyle-Narlikar-Wheeler proposition that neutron
star emerging in the magnetic-flux-conserving process of core-collapse
supernova can convert the stored energy of Alfven vibrations into power of
magneto-dipole radiation. We show that the necessary requirement for the energy
conversion is the decay of internal magnetic field. In this case the loss of
vibration energy of the star causes its vibration period, equal to period of
pulsating emission, to lengthen at a rate proportional to the rate of magnetic
field decay. These prediction of the model of vibration powered neutron star
are discussed in juxtaposition with data on pulsating emission of magnetars
whose radiative activity is generally associated with the decay of ultra strong
magnetic field.Comment: Accepted for publication in Astrophysics & Space Scienc
Phase Transitions of Hard Disks in External Periodic Potentials: A Monte Carlo Study
The nature of freezing and melting transitions for a system of hard disks in
a spatially periodic external potential is studied using extensive Monte Carlo
simulations. Detailed finite size scaling analysis of various thermodynamic
quantities like the order parameter, its cumulants etc. are used to map the
phase diagram of the system for various values of the density and the amplitude
of the external potential. We find clear indication of a re-entrant liquid
phase over a significant region of the parameter space. Our simulations
therefore show that the system of hard disks behaves in a fashion similar to
charge stabilized colloids which are known to undergo an initial freezing,
followed by a re-melting transition as the amplitude of the imposed, modulating
field produced by crossed laser beams is steadily increased. Detailed analysis
of our data shows several features consistent with a recent dislocation
unbinding theory of laser induced melting.Comment: 36 pages, 16 figure
Aspect-ratio dependence of the spin stiffness of a two-dimensional XY model
We calculate the superfluid stiffness of 2D lattice hard-core bosons at
half-filling (equivalent to the S=1/2 XY-model) using the squared winding
number quantum Monte Carlo estimator. For L_x x L_y lattices with aspect ratio
L_x/L_y=R, and L_x,L_y -> infinity, we confirm the recent prediction [N.
Prokof'ev and B.V. Svistunov, Phys. Rev. B 61, 11282 (1999)] that the
finite-temperature stiffness parameters \rho^W_x and \rho^W_y determined from
the winding number differ from each other and from the true superfluid density
\rho_s. Formally, \rho^W_y -> \rho_s in the limit in which L_x -> infinity
first and then L_y -> infinity. In practice we find that \rho^W_y converges
exponentially to \rho_s for R>1. We also confirm that for 3D systems, \rho^W_x
= \rho^W_y = \rho^W_z = \rho_s for any R. In addition, we determine the
Kosterlitz-Thouless transition temperature to be T_KT/J=0.34303(8) for the 2D
model.Comment: 7 pages, 8 figures, 1 table. Minor changes to published versio
The quantum J_{1}-J_{1'}-J_{2} spin-1/2 Heisenberg antiferromagnet: A variational method study
The phase transition of the quantum spin-1/2 frustrated Heisenberg
antiferroferromagnet on an anisotropic square lattice is studied by using a
variational treatment. The model is described by the Heisenberg Hamiltonian
with two antiferromagnetic interactions: nearest-neighbor (NN) with different
coupling strengths J_{1} and J_{1'} along x and y directions competing with a
next-nearest-neighbor coupling J_{2} (NNN). The ground state phase diagram in
the ({\lambda},{\alpha}) space, where {\lambda}=J_{1'}/J_{1} and
{\alpha}=J_{2}/J_{1}, is obtained. Depending on the values of {\lambda} and
{\alpha}, we obtain three different states: antiferromagnetic (AF), collinear
antiferromagnetic (CAF) and quantum paramagnetic (QP). For an intermediate
region {\lambda}_{1}<{\lambda}<1 we observe a QP state between the ordered AF
and CAF phases, which disappears for {\lambda} above some critical value
{\lambda}_{1}. The boundaries between these ordered phases merge at the quantum
critical endpoint (QCE). Below this QCE there is again a direct first-order
transition between the AF and CAF phases, with a behavior approximately
described by the classical line {\alpha}_{c}{\simeq}{\lambda}/2
Vortex dynamics for two-dimensional XY models
Two-dimensional XY models with resistively shunted junction (RSJ) dynamics
and time dependent Ginzburg-Landau (TDGL) dynamics are simulated and it is
verified that the vortex response is well described by the Minnhagen
phenomenology for both types of dynamics. Evidence is presented supporting that
the dynamical critical exponent in the low-temperature phase is given by
the scaling prediction (expressed in terms of the Coulomb gas temperature
and the vortex renormalization given by the dielectric constant
) both for RSJ and TDGL
and that the nonlinear IV exponent a is given by a=z+1 in the low-temperature
phase. The results are discussed and compared with the results of other recent
papers and the importance of the boundary conditions is emphasized.Comment: 21 pages including 15 figures, final versio
Scaling determination of the nonlinear I-V characteristics for 2D superconducting networks
It is shown from computer simulations that the current-voltage (-)
characteristics for the two-dimensional XY model with resistively-shunted
Josephson junction dynamics and Monte Carlo dynamics obeys a finite-size
scaling form from which the nonlinear - exponent can be determined to
good precision. This determination supports the conclusion , where
is the dynamic critical exponent. The results are discussed in the light of the
contrary conclusion reached by Tang and Chen [Phys. Rev. B {\bf 67}, 024508
(2003)] and the possibility of a breakdown of scaling suggested by Bormann
[Phys. Rev. Lett. {\bf 78}, 4324 (1997)].Comment: 6 pages, to appear in PR
Langevin Simulations of Two Dimensional Vortex Fluctuations: Anomalous Dynamics and a New -exponent
The dynamics of two dimensional (2D) vortex fluctuations are investigated
through simulations of the 2D Coulomb gas model in which vortices are
represented by soft disks with logarithmic interactions. The simulations
trongly support a recent suggestion that 2D vortex fluctuations obey an
intrinsic anomalous dynamics manifested in a long range 1/t-tail in the vortex
correlations. A new non-linear IV-exponent a, which is different from the
commonly used AHNS exponent, a_AHNS and is given by a = 2a_AHNS - 3, is
confirmed by the simulations. The results are discussed in the context of
earlier simulations, experiments and a phenomenological description.Comment: Submitted to PRB, RevTeX format, 28 pages and 13 figures, figures in
postscript format are available at http://www.tp.umu.se/~holmlund/papers.htm
Phase III study of pasireotide long-acting release in patients with metastatic neuroendocrine tumors and carcinoid symptoms refractory to available somatostatin analogues
In a randomized, double-blind, Phase III study, we compared pasireotide long-acting
release (pasireotide LAR) with octreotide long-acting repeatable (octreotide LAR) in managing
carcinoid symptoms refractory to first-generation somatostatin analogues. Adults with carcinoid
tumors of the digestive tract were randomly assigned (1:1) to receive pasireotide LAR (60 mg)
or octreotide LAR (40 mg) every 28 days. Primary outcome was symptom control based on
frequency of bowel movements and flushing episodes. Objective tumor response was a secondary
outcome. Progression-free survival (PFS) was calculated in a post hoc analysis. Adverse
events were recorded. At the time of a planned interim analysis, the data monitoring committee
recommended halting the study because of a low predictive probability of showing superiority
of pasireotide over octreotide for symptom control (n=43 pasireotide LAR, 20.9%; n=45
octreotide LAR, 26.7%; odds ratio, 0.73; 95% confidence interval [CI], 0.27–1.97; P=0.53).
Tumor control rate at month 6 was 62.7% with pasireotide and 46.2% with octreotide (odds
ratio, 1.96; 95% CI, 0.89–4.32; P=0.09). Median (95% CI) PFS was 11.8 months (11.0 – not
reached) with pasireotide versus 6.8 months (5.6 – not reached) with octreotide (hazard ratio,
0.46; 95% CI, 0.20–0.98; P=0.045). The most frequent drug-related adverse events (pasireotide
vs octreotide) included hyperglycemia (28.3% vs 5.3%), fatigue (11.3% vs 3.5%), and nausea
(9.4% vs 0%). We conclude that, among patients with carcinoid symptoms refractory to available
somatostatin analogues, similar proportions of patients receiving pasireotide LAR or octreotide
LAR achieved symptom control at month 6. Pasireotide LAR showed a trend toward higher
tumor control rate at month 6, although it was statistically not significant, and was associated
with a longer PFS than octreotide LAR
Enhanced stability of the square lattice of a classical bilayer Wigner crystal
The stability and melting transition of a single layer and a bilayer crystal
consisting of charged particles interacting through a Coulomb or a screened
Coulomb potential is studied using the Monte-Carlo technique. A new melting
criterion is formulated which we show to be universal for bilayer as well as
for single layer crystals in the case of (screened) Coulomb, Lennard--Jones and
1/r^{12} repulsive inter-particle interactions. The melting temperature for the
five different lattice structures of the bilayer Wigner crystal is obtained,
and a phase diagram is constructed as a function of the interlayer distance. We
found the surprising result that the square lattice has a substantial larger
melting temperature as compared to the other lattice structures. This is a
consequence of the specific topology of the defects which are created with
increasing temperature and which have a larger energy as compared to the
defects in e.g. a hexagonal lattice.Comment: Accepted for publication in Physical Review
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