Einsatz von Luzernetrockenblatt in der ökologischen Broilermast

In einem Fütterungsversuch sollte untersucht werden, wie sich eine sukzessive Steigerung der Luzerneblattanteile in Alleinfuttermischungen auf die Leistung von Masthühnern auswirkt und ob die Trocknungstemperatur des verwendeten Luzerneblatt­materials einen Einfluss auf den Futterverbrauch und die Gewichtsentwicklung der Tiere hat (Niedertemperaturtrocknung (LBnT) vs. Heißlufttrocknung (LB)). Es wurden 600 männliche Hubbard JA-757 Broiler auf 5 Fütterungsvarianten mit je 5 Wiederholungen verteilt (Kontrolle (K), LB 2, LB 3, LB 4, LBnT 5). Die Mast war in 3 Phasen unterteilt, die Anteile an Luzerneblattmehl wurden von Phase zu Phase um je 5% gesteigert (K: 0%-0%-0%; LB 2: 0%-5%-10%); LB 3: 5%-10%-15%; LB 4: 10%-15%-20%; LBnT 5: 10%-15%-20%). Die Tiere der Gruppe K erreichten das höchste Mastendgewicht. Die geringsten Gewichte zeigten die Gruppen LB 3, LB 4 und LBnT 5. Der Einsatz von Luzerneblattmehl, besonders der frühe Einsatz (5% ab Phase 1) und die Einmischung höherer Anteile (15-20%), führten zu signifikanten Leistungsdepressionen bei den wachsenden Broilern, welche vermutlich durch antinutritive Substanzen der Luzernepflanze (Saponine) ausgelöst wurden

Characterization of Hamamatsu 64-channel TSV SiPMs

The Hamamatsu UV-light enhanced 64-channel SiPM array of the newest generation (S13361-3050AS-08) has been examined for the purpose of being used for the Silicon Elementary Cell Add-on (SiECA) of the EUSO-SPB balloon experiment. Characterization measurements have been performed with the newly installed Single Photon Calibration Stand at KIT (SPOCK). The results of the characterization measurements including the breakdown voltage, the gain, the PDE, the dark-count rate and the crosstalk probability of all 64 SiPM channels are presented. Additional measurements of the SiPM sensitivity to photons with wavelengths lower than 400nm show an improved PDE for small wavelengths compared to the SiPM array S12642-0808PA-50, which was also investigated for comparison. The response dynamics have been investigated for low numbers of incoming photons. Temperature dependent measurements of the gain, the PDE, the dark-count rate and the crosstalk probability have been performed for one channel of the SiPM array.Comment: Accepted for publication in Nuclear Instruments and Methods

Synthetic antimicrobial and LPS-neutralising peptides suppress inflammatory and immune responses in skin cells and promote keratinocyte migration

The stagnation in the development of new antibiotics and the concomitant high increase of resistant bacteria emphasize the urgent need for new therapeutic options. Antimicrobial peptides are promising agents for the treatment of bacterial infections and recent studies indicate that Pep19-2.5, a synthetic anti-lipopolysaccharide (LPS) peptide (SALP), efficiently neutralises pathogenicity factors of Gram-negative (LPS) and Gram-positive (lipoprotein/-peptide, LP) bacteria and protects against sepsis. Here, we investigated the potential of Pep19-2.5 and the structurally related compound Pep19-4LF for their therapeutic application in bacterial skin infections. SALPs inhibited LP-induced phosphorylation of NF-κB p65 and p38 MAPK and reduced cytokine release and gene expression in primary human keratinocytes and dermal fibroblasts. In LPS-stimulated human monocyte-derived dendritic cells and Langerhans-like cells, the peptides blocked IL-6 secretion, downregulated expression of maturation markers and inhibited dendritic cell migration. Both SALPs showed a low cytotoxicity in all investigated cell types. Furthermore, SALPs markedly promoted cell migration via EGFR transactivation and ERK1/2 phosphorylation and accelerated artificial wound closure in keratinocytes. Peptide-induced keratinocyte migration was mediated by purinergic receptors and metalloproteases. In contrast, SALPs did not affect proliferation of keratinocytes. Conclusively, our data suggest a novel therapeutic target for the treatment of patients with acute and chronic skin infections

Produktivität, Narbendichte und Vegetation einer Kurzrasenweide

Productivity, sward structure and floristic diversity of a continuous grazed pasture on organic permanent grassland were determined in 2015. Daily pasture growth reached less than 50 kg dry matter per hectare in May and stayed low due to unfavorable weather conditions in 2015 (cold spring, dry and hot summer). Forage quality was quite high (> 6,5 MJ NEL/kg dm) most of the grazing season. Tiller density was moderate during summer but increased after sufficient rain in late summer. Perennial ryegrass, Kentucky bluegrass and white clover were the dominant plant species and yielded more the 85 % of dry matter

KASCADE: Astrophysical results and tests of hadronic interaction models

KASCADE is a multi-detector setup to get redundant information on single air shower basis. The information is used to perform multiparameter analyses to solve the threefold problem of the reconstruction of (i)the unknown primary energy, (ii) the primary mass, and (iii) to quantify the characteristics of the hadronic interactions in the air-shower development. In this talk recent results of the KASCADE data analyses are summarized concerning cosmic ray anisotropy studies, determination of flux spectra for different primary mass groups, and approaches to test hadronic interaction models. Neither large scale anisotropies nor point sources were found in the KASCADE data set. The energy spectra of the light element groups result in a knee-like bending and a steepening above the knee. The topology of the individual knee positions shows a dependency on the primary particle. Though no hadronic interaction model is fully able to describe the multi-parameter data of KASCADE consistently, the more recent models or improved versions of older models reproduce the data better than few years ago.Comment: to appear in Nucl. Phys. B (Proc. Suppl.), Proc. of the XIII ISVHECRI, Pylos 2004 - with a better quality of the figure

Dissecting the knee - Air shower measurements with KASCADE

Recent results of the KASCADE air shower experiment are presented in order to shed some light on the astrophysics of cosmic rays in the region of the knee in the energy spectrum. The results include investigations of high-energy interactions in the atmosphere, the analysis of the arrival directions of cosmic rays, the determination of the mean logarithmic mass, and the unfolding of energy spectra for elemental groups

2008-2009 President\u27s Report

The Linfield College President\u27s Annual Report is a collection of information about the year in review, including academics, student life and athletics, enrollment, finances, philanthropy, and leadership