9,056 research outputs found
Why Do Shoppers Use Cash? Evidence from Shopping Diary Data
Recent studies find that cash remains a dominant payment choice for small-value transactions despite the prevalence of alternative methods of payment such as debit and credit cards. For policy makers an important question is whether consumers truly prefer using cash or merchants restrict card usage. Using unique shopping diary data, we estimate a payment choice model with individual unobserved heterogeneity (demandside factors) while controlling for merchants’ acceptance of cards (supply-side factors). Based on a policy simulation where we impose universal card acceptance among merchants, we find that overall cash usage would decrease by only 7.7 percentage points, implying that cash usage in small-value transactions is driven mainly by consumers’ preferences
PGI2-Aerosol versus nitric oxide for selective pulmonary vasodilation in hypoxic pulmonary vasoconstriction
Photon-Mediated Quantum Gate between Two Trapped Neutral Atoms in an Optical Cavity
Quantum logic gates are fundamental building blocks of quantum computers.
Their integration into quantum networks requires strong qubit coupling to
network channels, as can be realized with neutral atoms and optical photons in
cavity quantum electrodynamics. Here we demonstrate that the long-range
interaction mediated by a flying photon performs a gate between two stationary
atoms inside an optical cavity from which the photon is reflected. This single
step executes the gate in . We show an entangling operation
between the two atoms by generating a Bell state with 76(2)% fidelity. The gate
also operates as a CNOT. We demonstrate 74.1(1.6)% overlap between the observed
and the ideal gate output, limited by the state preparation fidelity of
80.2(0.8)%. As the atoms are efficiently connected to a photonic channel, our
gate paves the way towards quantum networking with multiqubit nodes and the
distribution of entanglement in repeater-based long-distance quantum networks.Comment: 10 pages including appendix, 5 figure
Expression of VPAC1 in a murine model of allergic asthma
Vasoactive intestinal polypeptide (VIP) is a putative neurotransmitter of the inhibitory non-adrenergic non-cholinergic nervous system and influences the mammalian airway function in various ways. Hence known for bronchodilatory, immunomodulatory and mucus secretion modulating effects by interacting with the VIP receptors VPAC1 and VPAC2, it is discussed to be a promising target for pharmaceutical intervention in common diseases such as COPD and bronchial asthma. Here we examined the expression and transcriptional regulation of VPAC1 in the lungs of allergic mice using an ovalbumin (OVA) -induced model of allergic asthma. Mice were sensitized to OVA and challenged with an OVA aerosol. In parallel a control group was sham sensitized with saline. VPAC1 expression was examined using RT-PCR and real time-PCR studies were performed to quantify gene transcription. VPAC1 mRNA expression was detected in all samples of OVA-sensitized and challenged animals and control tissues. Further realtime analysis did not show significant differences at the transcriptional level.
Although the present studies did not indicate a major transcriptional regulation of VPAC1 in states of allergic airway inflammation, immunomodulatory effects of VPAC1 might still be present due to regulations at the translational level
Stochastic modeling of cargo transport by teams of molecular motors
Many different types of cellular cargos are transported bidirectionally along
microtubules by teams of molecular motors. The motion of this cargo-motors
system has been experimentally characterized in vivo as processive with rather
persistent directionality. Different theoretical approaches have been suggested
in order to explore the origin of this kind of motion. An effective theoretical
approach, introduced by M\"uller et al., describes the cargo dynamics as a
tug-of-war between different kinds of motors. An alternative approach has been
suggested recently by Kunwar et al., who considered the coupling between motor
and cargo in more detail. Based on this framework we introduce a model
considering single motor positions which we propagate in continuous time.
Furthermore, we analyze the possible influence of the discrete time update
schemes used in previous publications on the system's dynamic.Comment: Cenference proceedings - Traffic and Granular Flow 1
A photon-photon quantum gate based on a single atom in an optical resonator
Two photons in free space pass each other undisturbed. This is ideal for the
faithful transmission of information, but prohibits an interaction between the
photons as required for a plethora of applications in optical quantum
information processing. The long-standing challenge here is to realise a
deterministic photon-photon gate. This requires an interaction so strong that
the two photons can shift each others phase by pi. For polarisation qubits,
this amounts to the conditional flipping of one photon's polarisation to an
orthogonal state. So far, only probabilistic gates based on linear optics and
photon detectors could be realised, as "no known or foreseen material has an
optical nonlinearity strong enough to implement this conditional phase
shift..." [Science 318, 1567]. Meanwhile, tremendous progress in the
development of quantum-nonlinear systems has opened up new possibilities for
single-photon experiments. Platforms range from Rydberg blockade in atomic
ensembles to single-atom cavity quantum electrodynamics. Applications like
single-photon switches and transistors, two-photon gateways, nondestructive
photon detectors, photon routers and nonlinear phase shifters have been
demonstrated, but none of them with the ultimate information carriers, optical
qubits. Here we employ the strong light-matter coupling provided by a single
atom in a high-finesse optical resonator to realise the Duan-Kimble protocol of
a universal controlled phase flip (CPF, pi phase shift) photon-photon quantum
gate. We achieve an average gate fidelity of F=(76.2+/-3.6)% and specifically
demonstrate the capability of conditional polarisation flipping as well as
entanglement generation between independent input photons. Our gate could
readily perform most of the hitherto existing two-photon operations. It also
discloses avenues towards new quantum information processing applications where
photons are essential.Comment: 7 pages, 5 figure
Deterministic creation of entangled atom-light Schr\"odinger-cat states
Quantum physics allows for entanglement between microscopic and macroscopic
objects, described by discrete and continuous variables, respectively. As in
Schr\"odinger's famous cat gedanken experiment, a box enclosing the objects can
keep the entanglement alive. For applications in quantum information
processing, however, it is essential to access the objects and manipulate them
with suitable quantum tools. Here we reach this goal and deterministically
generate entangled light-matter states by reflecting a coherent light pulse
with up to four photons on average from an optical cavity containing one atom.
The quantum light propagates freely and reaches a remote receiver for quantum
state tomography. We produce a plethora of quantum states and observe
negative-valued Wigner functions, a characteristic sign of non-classicality. As
a first application, we demonstrate a quantum-logic gate between an atom and a
light pulse, with the photonic qubit encoded in the phase of the light field.Comment: includes Methods and Supplementary Informatio
The role of microtubule movement in bidirectional organelle transport
We study the role of microtubule movement in bidirectional organelle
transport in Drosophila S2 cells and show that EGFP-tagged peroxisomes in cells
serve as sensitive probes of motor induced, noisy cytoskeletal motions.
Multiple peroxisomes move in unison over large time windows and show
correlations with microtubule tip positions, indicating rapid microtubule
fluctuations in the longitudinal direction. We report the first high-resolution
measurement of longitudinal microtubule fluctuations performed by tracing such
pairs of co-moving peroxisomes. The resulting picture shows that
motor-dependent longitudinal microtubule oscillations contribute significantly
to cargo movement along microtubules. Thus, contrary to the conventional view,
organelle transport cannot be described solely in terms of cargo movement along
stationary microtubule tracks, but instead includes a strong contribution from
the movement of the tracks.Comment: 24 pages, 5 figure
Cavity Carving of Atomic Bell States
We demonstrate entanglement generation of two neutral atoms trapped inside an
optical cavity. Entanglement is created from initially separable two-atom
states through carving with weak photon pulses reflected from the cavity. A
polarization rotation of the photons heralds the entanglement. We show the
successful implementation of two different protocols and the generation of all
four Bell states with a maximum fidelity of (90+-2)%. The protocol works for
any distance between cavity-coupled atoms, and no individual addressing is
required. Our result constitutes an important step towards applications in
quantum networks, e.g. for entanglement swapping in a quantum repeater.Comment: 9 pages, 7 figures including Supplemen
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